| ALASKA NATIVE TRIBAL HEALTH CONSORTIUM | Anchorage | E220 Health Care | $1.1B | 26 |
| Southcentral Foundation | Anchorage | E31 Health Care | $633.7M | 16 |
| CENTRAL PENINSULA GENERAL HOSPITAL INC | Soldotna | E220 Health Care | $606.2M | 24 |
| SOUTHEAST ALASKA REGIONAL HEALTH | Juneau | E300 Health Care | $404.2M | 29 |
| FOUNDATION HEALTH LLC | Fairbanks | E20 Health Care | $401.3M | 21 |
| CHUGACH ELECTRIC ASSOCIATION INC | Anchorage | — | $365.1M | 21 |
| Golden Valley Electric Association Inc | Fairbanks | — | $295.9M | 21 |
| NORTON SOUND HEALTH CORPORATION | Nome | E21Z Health Care | $248.3M | 39 |
| Bristol Bay Area Health Corporation | Dillingham | E300 Health Care | $187.7M | 45 |
| Maniilaq Association | Kotzebue | P840 Human Services | $176.1M | 26 |
| MATANUSKA ELECTRIC ASSOCIATION INC | Palmer | — | $166.1M | 15 |
| ARCTIC SLOPE NATIVE ASSOCIATION | Barrow | Z99Z Unknown | $145M | 20 |
| SOUTH PENINSULA HOSPITAL INC | Homer | E22Z Health Care | $113.5M | 22 |
| Homer Electric Association Inc | Homer | — | $109M | 18 |
| Credit Union 1 | Anchorage | — | $100.7M | 11 |
| PUBLIC EDUCATION HEALTH TRUST | Anchorage | Y43 Mutual & Membership Benefit | $99.7M | 1 |
| Alaska Village Electric Cooperative Inc | Anchorage | — | $93.3M | 16 |
| ALASKA ELECTRICAL HEALTH & WELFARE | Anchorage | — | $83.9M | 2 |
| Cook Inlet Tribal Council | Anchorage | P840 Human Services | $72.4M | 32 |
| Alaska Electric and Energy Cooperative Inc | Homer | W50 Public & Societal Benefit | $69.8M | 3 |
| RASMUSON FOUNDATION | Anchorage | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $69.3M | 4 |
| VALLEY HOSPITAL ASSOCIATION INC | Wasilla | E220 Health Care | $59.6M | 8 |
| Child Care Connection Inc | Anchorage | P33Z Human Services | $58.5M | 4 |
| KAWERAK INC | Nome | — | $56.2M | 37 |
| Kodiak Area Native Association | Kodiak | P200 Human Services | $53.8M | 18 |
| COASTAL VILLAGES REGION FUND | Anchorage | S20 Community Improvement & Capacity Building | $51.5M | 41 |
| THE GREATER FAIRBANKS COMMUNITY | Fairbanks | E110 Health Care | $48.3M | 4 |
| Hope Community Resources Inc | Anchorage | F33Z Mental Health & Crisis Intervention | $40.7M | 8 |
| ALASKA TEAMSTER EMPLOYER WELFARE TRUST | Anchorage | — | $40.3M | 3 |
| RURAL ALASKA COMMUNITY ACTION PROGRAM | Anchorage | S200 Community Improvement & Capacity Building | $38.8M | 9 |
| ANCHORAGE COMMUNITY MENTAL HEALTH | Anchorage | F320 Mental Health & Crisis Intervention | $36.1M | 7 |
| ALASKA PUBLIC SERVICE EMPLOYEES | Anchorage | — | $35.4M | 0 |
| ALEUTIAN PRIBILOF ISLANDS | Anchorage | S200 Community Improvement & Capacity Building | $34.8M | 22 |
| Barrow Utilities and Electric Coop | Barrow | — | $33.4M | 16 |
| Alaska Clean Seas | Anchorage | — | $31.3M | 12 |
| COPPER VALLEY ELECTRIC ASSOCIATION INC | Glennallen | — | $30.4M | 17 |
| CHUGACHMIUT | Anchorage | P200 Human Services | $30.2M | 14 |
| Kodiak Electric Association Inc | Kodiak | — | $28M | 16 |
| Fairbanks Native Association | Fairbanks | F220 Mental Health & Crisis Intervention | $27.4M | 21 |
| The Alaska Community Foundation | Anchorage | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $27.2M | 7 |
| CATHOLIC SOCIAL SERVICES | Anchorage | P200 Human Services | $26.6M | 0 |
| Copper River Native Association Inc | Glennallen | Z99Z Unknown | $26.3M | 21 |
| Bristol Bay Native Association Inc | Dillingham | P200 Human Services | $25.6M | 40 |
| SEALASKA HERITAGE INSTITUTE | Juneau | A230 Arts, Culture & Humanities | $24.7M | 7 |
| Alaska Pacific University | Anchorage | B430 Education | $24.6M | 10 |
| Petersburg Medical Center | Petersburg | W20 Public & Societal Benefit | $24.5M | 37 |
| Tlingit-Haida Regional Housing Authority | Juneau | L210 Housing & Shelter | $23.6M | 13 |
| ANCHORAGE NEIGHBORHOOD HEALTH CENTER INC | Anchorage | E320 Health Care | $23.3M | 11 |
| UNIVERSITY OF ALASKA FOUNDATION | Anchorage | B110 Education | $23.1M | 12 |
| Southern Southeast Regional Aquaculture | Ketchikan | D330 Animal-Related | $22.1M | 17 |
