| CEDARS YOUTH SERVICES INC | Lincoln | A20M Arts, Culture & Humanities | $18.2M | 4 |
| TOGETHER INC OF METROPOLITAN OMAHA | Omaha | P60Z Human Services | $18.1M | 3 |
| NEBRASKA HUMANE SOCIETY | Omaha | D200 Animal-Related | $18.1M | 8 |
| IRC II INC | Omaha | L21 Housing & Shelter | $18M | 9 |
| WEST HOLT MEMORIAL HOSPITAL | Atkinson | — | $17.9M | 7 |
| COMMUNITY ALLIANCE REHABILITATION SERVICES | Omaha | E99L Health Care | $17.6M | 5 |
| COMMUNITY ALLIANCE INC | Omaha | — | $17.2M | 3 |
| COMMUNITY ACTION PARTNERSHIP OF WESTERN NEBRASKA | Gering | P20 Human Services | $17M | 7 |
| NEBRASKA STATE FAIR BOARD | Grand Island | — | $16.9M | 1 |
| JEWISH FEDERATION OF OMAHA FOUNDATION | Omaha | T12 Philanthropy, Voluntarism & Grantmaking Foundations | $16.8M | 1 |
| CENTERPOINTE INC | Lincoln | F20L Mental Health & Crisis Intervention | $16.8M | 6 |
| CHN NEBRASKA | Omaha | E60 Health Care | $16.4M | 5 |
| Collective For Youth | Omaha | B90 Education | $16.3M | 1 |
| REGIONAL WEST HEALTH SERVICES & AFFILIATE | Scottsbluff | — | $16.3M | 7 |
| HEART MINISTRY CENTER | Omaha | K31 Food, Agriculture & Nutrition | $16.3M | 6 |
| MENTAL HEALTH INNOVATION FOUNDATION | Omaha | E12 Health Care | $16.2M | 0 |
| DIALYSIS CENTER OF LINCOLN INC | Lincoln | E300 Health Care | $16M | 7 |
| THE CHARLES AND MARY HEIDER FAMILY FOUNDATION | Omaha | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $15.8M | 2 |
| FAMILY SERVICE ASSOCIATION OF LINCOLN | Lincoln | P40Z Human Services | $15.7M | 2 |
| CENTRAL NEBRASKA COMMUNITY ACTION PARTNE | Loup City | — | $15.7M | 1 |
| MODERN AG ALLIANCE | Omaha | — | $15.6M | 0 |
| MID-NEBRASKA INDIVIDUAL SERVICES INC | Hastings | P820 Human Services | $15.4M | 1 |
| IOWA HEALTH INFORMATION NETWORK | La Vista | E99 Health Care | $15.3M | 2 |
| EDUCARE OF OMAHA INC | Omaha | B21 Education | $15.2M | 4 |
| CHRISTIAN RETIREMENT HOMES | Lincoln | — | $15.1M | 4 |
| REGIONAL WEST HEALTH SERVICES | Scottsbluff | E19 Health Care | $15.1M | 12 |
| NEBRASKA EARLY CHILDHOOD COLLABORATIVE | Omaha | — | $15.1M | 7 |
| NEBRASKA STUDENT LOAN PROGRAM INC | Lincoln | B820 Education | $15M | 17 |
| CENTER FOR RURAL AFFAIRS | Lyons | — | $14.8M | 6 |
| MOSAIC SENIOR SERVICES INC | Omaha | E99 Health Care | $14.7M | 5 |
| FLORENCE HOME FOR THE AGED | Omaha | P75 Human Services | $14.7M | 2 |
| ALEGENT HEALTH-MEMORIAL HOSPITAL SCHUYLER | Schuyler | — | $14.7M | 16 |
| HEARTLAND HOPE MISSION | Omaha | P20 Human Services | $14.6M | 2 |
| Union Bank and Trust Company Welfare Benefits Trust | Lincoln | Y43 Mutual & Membership Benefit | $14.4M | 0 |
| CHILD SAVING INSTITUTE INC | Omaha | P30 Human Services | $14.3M | 5 |
| NEBRASKA METHODIST HOSPITAL FOUNDATION | Omaha | E110 Health Care | $14.3M | 6 |
| GOOD NEIGHBOR COMMUNITY HEALTH CENTER | Columbus | E21 Health Care | $14.1M | 1 |
| Midtown Health Center | Norfolk | E20 Health Care | $14M | 7 |
| HAPPY HOLLOW CLUB | Omaha | — | $14M | 7 |
| BOYS & GIRLS CLUBS OF THE MIDLANDS | Omaha | O230 Youth Development | $13.4M | 8 |
| NEBRASKA PUBLIC MEDIA FOUNDATION INC | Lincoln | A12 Arts, Culture & Humanities | $13.3M | 5 |
| KVC BEHAVIORAL HEALTHCARE NEBRASKA INC | Omaha | E60 Health Care | $13.3M | 6 |
| BLUE VALLEY COMMUNITY ACTION INC | Fairbury | P200 Human Services | $13M | 2 |
| COMMUNITY ACTION PARTNERSHIP OF MID-NEBRASKA | Kearney | — | $13M | 2 |
| LINCOLN YOUTH COMPLEX | Lincoln | N31 Recreation & Sports | $13M | 1 |
| UNeHealth | Omaha | E30Z Health Care | $12.9M | 8 |
| CONTRACTORS LABORERS TEAMSTERS& ENGINEERS HEALTH & WELFARE PLAN | Omaha | — | $12.9M | 0 |
| REGION I OFFICE OF HUMAN DEVELOPMEN | Scottsbluff | P820 Human Services | $12.8M | 1 |
| Omaha Botanical Center Inc | Omaha | C114 Environment | $12.3M | 6 |
| PRODUCERS LIVESTOCK CREDIT CORPORATION | Omaha | — | $12.3M | 4 |
