| DISCOVERY PLACE INC | Charlotte | A570 Arts, Culture & Humanities | $14.1M | 11 |
| ONSLOW COUNTY PARTNERSHIP FOR CHILDREN | Jacksonville | B012 Education | $14M | 6 |
| LEITH INC VOLUNTARY EES BENEFICIARY | Raleigh | — | $13.9M | 0 |
| High Point International Home Furnishing | High Point | S41 Community Improvement & Capacity Building | $13.9M | 4 |
| CHARLOTTE REGIONAL REALTOR | Charlotte | — | $13.9M | 23 |
| Lutheran Home - Wilmington Inc | Salisbury | — | $13.9M | 5 |
| NORTH CAROLINA ASSOCIATION OF | Raleigh | — | $13.9M | 6 |
| KIPP CHARLOTTE INC | Charlotte | B25 Education | $13.8M | 1 |
| EAST WAKE FIRST CHARTER SCHOOL | Zebulon | B24 Education | $13.7M | 0 |
| NC STATE ENGINEERING FOUNDATION INC | Raleigh | B124 Education | $13.7M | 5 |
| FALLS LAKE ACADEMY | Creedmoor | B29 Education | $13.7M | 1 |
| The C W Williams Community Health Center | Charlotte | E320 Health Care | $13.6M | 1 |
| ALAMANCE EXTENDED CARE INC | Greensboro | L22 Housing & Shelter | $13.6M | 4 |
| Lutheran Home - Winston-Salem Inc | Salisbury | E91Z Health Care | $13.6M | 4 |
| NORTH CAROLINA COASTAL FEDERATION INC | Newport | — | $13.6M | 5 |
| Young Men's Christian Association of | Wilmington | P27Z Human Services | $13.5M | 2 |
| Housing Collaborative | Charlotte | L80 Housing & Shelter | $13.4M | 1 |
| Excelsior Classical Academy A Challenge Foundation Academy INC | Durham | B29 Education | $13.4M | 2 |
| NC COUNTS COALITION | Raleigh | B90 Education | $13.3M | 1 |
| COUNTRY CLUB OF SAPPHIRE VALLEY INC | Cashiers | — | $13.3M | 4 |
| Make North Carolina First | Raleigh | — | $13.3M | 0 |
| KINSTON COMMUNITY HEALTH CENTER INC | Kinston | E32Z Health Care | $13.2M | 10 |
| Lutheran Home - Forsyth County Inc | Salisbury | — | $13.2M | 8 |
| Pinnacle Classical Academy | Shelby | B29 Education | $13.1M | 4 |
| DURHAM'S PARTNERSHIP FOR CHILDREN | Durham | B012 Education | $13.1M | 1 |
| NUCOR CHARITABLE FOUNDATION | Charlotte | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $13M | 0 |
| Asheville Christian Academy Inc | Swannanoa | B24Z Education | $13M | 2 |
| TRINITY EPISCOPAL SCHOOL | Charlotte | B20 Education | $13M | 4 |
| PRESBYTERIAN HOSPITAL FOUNDATION | Winston Salem | E22I Health Care | $12.9M | 12 |
| AGING DISABILITY & TRANSIT SERVICES | Reidsville | — | $12.9M | 1 |
| Alpha Academy INC | Fayetteville | B29 Education | $12.8M | 0 |
| FOUNDATION FOR HEALTH LEADERSHIP AND | Cary | — | $12.8M | 5 |
| CHILDREN'S ADVOCACY CENTERS OF NORTH | Graham | I72 Crime & Legal-Related | $12.8M | 2 |
| American Board of Orthopaedic Surgery | Chapel Hill | — | $12.8M | 24 |
| COMMUNITY ACTION OPPORTUNITIES | Asheville | P20 Human Services | $12.8M | 4 |
| The Center for Black Health and Equity | Durham | F52 Mental Health & Crisis Intervention | $12.8M | 1 |
| SISTERS OF MERCY URGENT CARE INC | Asheville | — | $12.7M | 9 |
| HOSPICE OF GASTON COUNTY INC | Gastonia | — | $12.6M | 8 |
| THREE RIVERS LAND TRUST INC | Salisbury | C340 Environment | $12.6M | 1 |
| NORTH CAROLINA ALLIANCE OF PUBLIC | Raleigh | E99Z Health Care | $12.6M | 3 |
| BREVARD MUSIC CENTER INCORPORATED | Brevard | — | $12.5M | 5 |
| NORTH CAROLINA ASSOCIATION OF | Greensboro | — | $12.5M | 10 |
| PURPLE HEART HOMES INC | Statesville | W30 Public & Societal Benefit | $12.5M | 4 |
| CUMBERLAND COMMUNITY FOUNDATION INC | Fayetteville | T31Z Philanthropy, Voluntarism & Grantmaking Foundations | $12.5M | 2 |
| HARBORPATH INC | Charlotte | G81 Diseases, Disorders & Medical Disciplines | $12.4M | 1 |
| PAVILLON INTERNATIONAL | Mill Spring | F20Z Mental Health & Crisis Intervention | $12.4M | 9 |
| Davidson Day School | Davidson | B24 Education | $12.4M | 4 |
| SOUTHWESTERN CHILD DEVELOPMENT | Webster | — | $12.4M | 2 |
| BlueWest Opportunities Inc | Asheville | G84Z Diseases, Disorders & Medical Disciplines | $12.3M | 2 |
| College Preparatory and Leadership Academy of High Point | Jamestown | O54 Youth Development | $12.2M | 1 |
