| WILLAMETTE FAMILY MEDICAL CENTER INC | Salem | E39Z Health Care | $32.2M | 7 |
| Mennonite Home of Albany Inc | Albany | P750 Human Services | $32.1M | 9 |
| CRAFT3 | Astoria | S43 Community Improvement & Capacity Building | $32.1M | 14 |
| Dallas Mennonite Retirement Community | Dallas | L22 Housing & Shelter | $31.9M | 6 |
| SOUTHERN OREGON GOODWILL INDUSTRIES INC | Medford | J32Z Employment | $31.9M | 7 |
| SELF ENHANCEMENT INC | Portland | Z99Z Unknown | $31.7M | 9 |
| CODA INC | Portland | F22Z Mental Health & Crisis Intervention | $31.5M | 6 |
| NEW NARRATIVE | Tigard | P73Z Human Services | $31.3M | 8 |
| OREGON CHARTER ACADEMY | Mill City | B80 Education | $31.2M | 3 |
| PROVIDENCE PORTLAND MEDICAL FOUNDATION | Portland | E112 Health Care | $31.1M | 2 |
| TRAVEL PORTLAND | Portland | — | $30.9M | 5 |
| University of Western States | Portland | G93Z Diseases, Disorders & Medical Disciplines | $30.9M | 16 |
| BESTCARE TREATMENT SERVICES INC | Redmond | E60 Health Care | $30.7M | 8 |
| BibleProject | Portland | X99 Religion-Related | $30.6M | 11 |
| ALBINA HEAD START INC | Portland | Z99 Unknown | $30.6M | 2 |
| WILLAMETTE HEALTH COUNCIL | Salem | E60 Health Care | $30.6M | 0 |
| SISKIYOU COMMUNITY HEALTH CENTER INC | Grants Pass | — | $30.6M | 10 |
| REACH COMMUNITY DEVELOPMENT INC | Portland | L200 Housing & Shelter | $30.4M | 8 |
| OREGON EDUCATION ASSOCIATION | Portland | J40 Employment | $30.2M | 27 |
| MERCY FLIGHTS INC | Medford | E63Z Health Care | $30.2M | 8 |
| CENTRAL WILLAMETTE CREDIT UNION | Albany | — | $30M | 11 |
| LIFEWAYS INC | Ontario | F30 Mental Health & Crisis Intervention | $29.6M | 7 |
| LANE ELECTRIC COOPERATIVE INC | Eugene | — | $29.5M | 15 |
| HABITAT FOR HUMANITY PORTLAND METRO EAST | Portland | L20 Housing & Shelter | $29.1M | 7 |
| OREGON HUMANE SOCIETY | Portland | D200 Animal-Related | $28.9M | 7 |
| Latino Network | Portland | P84 Human Services | $28.7M | 6 |
| CASCADE AIDS PROJECT | Portland | G81Z Diseases, Disorders & Medical Disciplines | $28.7M | 10 |
| PARTNERS IN CARE | Bend | P74 Human Services | $28.6M | 9 |
| DURBAN FAMILY FOUNDATION | Beaverton | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $28.5M | 0 |
| LOCAL UNION 598 PLUMBING & PIPEFITTING | Portland | — | $27.7M | 0 |
| HUMAN SOLUTIONS INC | Portland | S200 Community Improvement & Capacity Building | $27.4M | 2 |
| MIRABELLA AT SOUTH WATERFRONT | Portland | L22 Housing & Shelter | $27.4M | 6 |
| Oregon Homecare Workers Benefit Trust | Portland | Y43 Mutual & Membership Benefit | $27.4M | 0 |
| VOCATIONAL DEVELOPMENT FOUNDATION | Portland | J30 Employment | $27.4M | 0 |
| BUSHNELL UNIVERSITY | Eugene | B43Z Education | $26.9M | 7 |
| MARION-POLK FOOD SHARE INC | Salem | K31Z Food, Agriculture & Nutrition | $26.8M | 3 |
| OREGON MUSEUM OF SCIENCE AND INDUSTRY | Portland | A570 Arts, Culture & Humanities | $26.7M | 8 |
| SHANGRI-LA CORPORATION | Salem | P200 Human Services | $26.3M | 5 |
| PACIFIC RETIREMENT SERVICES INC | Medford | P027 Human Services | $26.3M | 14 |
| Capital Manor Inc | Salem | P750 Human Services | $26.1M | 6 |
| CANBY TELEPHONE ASSOCIATION | Mt Angel | — | $25.9M | 12 |
| SEEDING JUSTICE | Portland | T22Z Philanthropy, Voluntarism & Grantmaking Foundations | $25.7M | 6 |
| SOUTHERN OREGON CHILD AND FAMILY | Central Point | B20 Education | $25.6M | 3 |
| DELPHI SCHOOLS INC | Sheridan | B20 Education | $25.4M | 5 |
| Columbia Community Mental Health Inc | St Helens | F320 Mental Health & Crisis Intervention | $25.4M | 6 |
| ALTERNATIVE SERVICES - OR INC | Tigard | P730 Human Services | $25.1M | 13 |
| HOLT INTERNATIONAL CHILDREN'S SERVICES | Eugene | P31 Human Services | $25.1M | 7 |
| Friendsview Manor | Newberg | P750 Human Services | $25M | 6 |
| WILLAMETTE COMMUNITY HEALTH | Eugene | E22 Health Care | $24.9M | 8 |
| URBAN LEAGUE OF PORTLAND INC | Portland | P22Z Human Services | $24.7M | 5 |
