| THE LUBERT FAMILY FOUNDATION INC | Philadelphia | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $20.6M | 1 |
| NATIONAL NURSE-LED CARE CONSORTIUM | Philadelphia | E02 Health Care | $20.6M | 2 |
| POST-RETIREMENT BENEFIT TRUST FOR SHARED | Pittsburgh | Y43 Mutual & Membership Benefit | $20.6M | 0 |
| UNITED COMMUNITY INDEPENDENCE PROGRAMS | Meadville | P82Z Human Services | $20.5M | 4 |
| VIECARE BUTLER LLC | Cranberry Township | L20 Housing & Shelter | $20.5M | 7 |
| LANCASTER COUNTRY DAY SCHOOL | Lancaster | B24Z Education | $20.5M | 7 |
| KIPP PHILADELPHA CHARTER SCHOOL | Philadelphia | B21 Education | $20.4M | 7 |
| TRUENORTH WELLNESS SERVICES | Hanover | F220 Mental Health & Crisis Intervention | $20.4M | 6 |
| FRIENDSHIP HOUSE | Scranton | P300 Human Services | $20.3M | 5 |
| COMMUNITY HEALTH & DENTAL CARE INC | Pottstown | E20 Health Care | $20.3M | 10 |
| THE WAWA FOUNDATION INC | Wawa | P20 Human Services | $20.3M | 0 |
| PENNSYLVANIA ASSOCIATION OF REGIONAL | Pittsburgh | — | $20.3M | 1 |
| SCOTT FOUNDATION INC | Greensburg | T21 Philanthropy, Voluntarism & Grantmaking Foundations | $20.2M | 0 |
| GREATER VALLEY YOUNG MEN'S | Allentown | — | $20.2M | 2 |
| STONERIDGE RETIREMENT LIVING | Myerstown | P750 Human Services | $20.2M | 1 |
| ECUMENICAL ENTERPRISES INC | Dallas | P120 Human Services | $20.2M | 6 |
| THE CAHOUET FOUNDATION TR | Pittsburgh | T90 Philanthropy, Voluntarism & Grantmaking Foundations | $20.2M | 1 |
| PROSPECTUS ASSOCIATES INC | Reading | P80Z Human Services | $20.2M | 5 |
| COMMUNITY RESOURCES FOR INDEPENDENCE | Erie | — | $20.1M | 5 |
| TOWER HEALTH AT HOME | Reading | E92Z Health Care | $20.1M | 9 |
| GERMANTOWN HOME | Philadelphia | E910 Health Care | $20.1M | 5 |
| OLD ORDER AMISH HELPING PROGRAM | Elizabethville | P60 Human Services | $20.1M | 3 |
| UNITED FOOD & COMMERCIAL WORKERS | Plymouth Meeting | — | $20M | 3 |
| PENNON ORGANIZATION | Harrisburg | A300 Arts, Culture & Humanities | $20M | 10 |
| THE COLLEGE OF PHYSICIANS OF | Philadelphia | — | $20M | 6 |
| THE REHABILITATION GROUP OF PENNSYLVANIA | Bala Cynwyd | — | $20M | 10 |
| THE WILLIAMSPORT HOME | Williamsport | — | $19.9M | 4 |
| ROLLING ROCK CLUB | Ligonier | — | $19.8M | 9 |
| FIRST COMMUNITY FOUNDATION PARTNERSHIP | Williamsport | T310 Philanthropy, Voluntarism & Grantmaking Foundations | $19.8M | 2 |
| YORK ACADEMY REGIONAL CHARTER SCHOOL | York | B29 Education | $19.8M | 5 |
| PLANNED PARENTHOOD SOUTHEASTERN PA | Philadelphia | E42 Health Care | $19.8M | 7 |
| GEORGE JUNIOR REPUBLIC IN PENNSYLVANIA | Grove City | F33Z Mental Health & Crisis Intervention | $19.8M | 7 |
| THRESHOLD REHABILITATION SERVICES INC | Reading | J300 Employment | $19.8M | 10 |
| GOODWILL OF THE SOUTHERN ALLEGHENIES | Johnstown | — | $19.8M | 1 |
| POSNER FOUNDATION OF PITTSBURGH | Pittsburgh | — | $19.7M | 0 |
| NEW HERITAGE TOWERS | Warminster | — | $19.6M | 8 |
| GARVEY MANOR NURSING HOME | Hollidaysburg | — | $19.6M | 5 |
| ST ANNE HOME | Greensburg | E910 Health Care | $19.6M | 5 |
| SECOND HARVEST FOOD BANK OF NW PA INC | Erie | K31Z Food, Agriculture & Nutrition | $19.6M | 1 |
| VALLEY VIEW HAVEN INC | Belleville | L20 Housing & Shelter | $19.6M | 5 |
| THE HEART GROUP OF LANCASTER GENERAL HEALTH | Lancaster | G43 Diseases, Disorders & Medical Disciplines | $19.5M | 16 |
| BARNES-KASSON COUNTY HOSPITAL | Susquehanna | E22 Health Care | $19.5M | 10 |
| SPIRIT PHYSICIAN SERVICES INC | Hershey | — | $19.5M | 17 |
| GREATER PHILADELPHIA TOURISM MARKETING | Philadelphia | S30 Community Improvement & Capacity Building | $19.5M | 9 |
| Propel Charter School Sunrise | Pittsburgh | B29 Education | $19.5M | 4 |
| STAPELEY HALL | Warminster | Z99Z Unknown | $19.4M | 8 |
| Propel Charter School-Montour | Pittsburgh | B20 Education | $19.4M | 5 |
| MAIN LINE HEALTH SYSTEM | Newtown Square | E210 Health Care | $19.3M | 4 |
| MASTERY CHARTER SCHOOL-SHOEMAKER CAMPUS | Philadelphia | B29 Education | $19.3M | 6 |
| HOFFMAN HOMES INC | Littlestown | P34B Human Services | $19.2M | 2 |
