| GREENHEART INTERNATIONAL | Chicago | Q220 International, Foreign Affairs & National Security | $11.2M | 0 |
| NORTHERN ILLINOIS BLOOD BANK INC | Rockford | E61Z Health Care | $11.2M | 4 |
| DESCENDANTS TRUTH&RECONCILIATION TR | Chicago | R22 Civil Rights, Social Action & Advocacy | $11.2M | 1 |
| VIVO FOUNDATION | Northbrook | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $11.2M | 0 |
| THE PROJECT OF THE QUAD CITIESINC | Moline | S80Z Community Improvement & Capacity Building | $11.2M | 2 |
| THE GRAINGER FOUNDATION INC | Lake Forest | — | $11.2M | 6 |
| Klaff Family Foundation | Chicago | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $11.1M | 0 |
| THE CHICAGO MATH & SCIENCE ACADEMY | Chicago | B29 Education | $11.1M | 2 |
| PIONEER CONCEPTS INC | Galesburg | L99 Housing & Shelter | $11.1M | 0 |
| Square One Foundation | Chicago | — | $11.1M | 0 |
| ACCREDITATION COUNCIL FOR CONTINUING | Chicago | B60 Education | $11.1M | 7 |
| EDEN RETIREMENT CENTER INC | Glen Carbon | L22Z Housing & Shelter | $11.1M | 2 |
| AMERICAN MEDICAL TECHNOLOGISTS | Rosemont | — | $11.1M | 20 |
| THE CHICAGO BAR FOUNDATION | Chicago | B990 Education | $11.1M | 2 |
| Hospital Sisters Services Inc | Springfield | — | $11.1M | 4 |
| BOOTH FERRIS FOUNDATION XXXXX4008 | Chicago | — | $11M | 1 |
| FIELD FOUNDATION OF ILLINOIS | Chicago | — | $11M | 2 |
| JAMES S AND PAULA H CROWN FAMILY FOUNDAT | Chicago | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $11M | 0 |
| N2 STONE FOUNDATION | Chicago | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $11M | 0 |
| FEDERAL DEFENDER PROGRAM INC | Chicago | — | $10.9M | 6 |
| WILLOWS HEALTH CENTER | Rockford | E910 Health Care | $10.9M | 4 |
| PEPPER FAMILY FOUNDATION | Chicago | — | $10.9M | 7 |
| CHICAGO JEWISH DAY SCHOOL | Chicago | B20 Education | $10.9M | 5 |
| Environmental Law and Policy Center of | Chicago | C30Z Environment | $10.9M | 7 |
| THE NEWBERRY LIBRARY | Chicago | B700 Education | $10.9M | 9 |
| TRUENU | Bartlett | T99 Philanthropy, Voluntarism & Grantmaking Foundations | $10.9M | 1 |
| Dominion Energy Inc Transmission Union | Chicago | Y430 Mutual & Membership Benefit | $10.9M | 1 |
| COMMUNITY ACTION PARTNERSHIP OF CENTRAL | Lincoln | P200 Human Services | $10.9M | 1 |
| SAFE FAMILIES FOR CHILDREN ALLIANCE | Chicago | P30 Human Services | $10.9M | 3 |
| DAVID F & MARGARET T GROHNE | Western Springs | T99Z Philanthropy, Voluntarism & Grantmaking Foundations | $10.9M | 0 |
| BILL BARTHOLOMAY FOUNDATION | Chicago | — | $10.8M | 0 |
| American College of Healthcare | Chicago | S41 Community Improvement & Capacity Building | $10.8M | 15 |
| ROMANIAN AMERICAN COMMUNITY CENTER | Chicago | P81 Human Services | $10.8M | 2 |
| MIDWEST REGION ORGANIZING COMMITTEE | Springfield | J40 Employment | $10.8M | 7 |
| RIVER FOREST COUNTRY CLUB | Elmhurst | N50 Recreation & Sports | $10.8M | 6 |
| THE CHICAGO COUNCIL ON GLOBAL AFFAIRS | Chicago | Q050 International, Foreign Affairs & National Security | $10.8M | 8 |
| NORTHERN KANE EDUCATIONAL CORP | Pingree Grove | B29 Education | $10.8M | 5 |
| ERIE NEIGHBORHOOD HOUSE | Chicago | P280 Human Services | $10.8M | 2 |
| MercyHealth Visiting Nurses Association Inc | Rockford | E92Z Health Care | $10.8M | 10 |
| ALZHEIMER'S IMPACT MOVEMENT | Chicago | G83 Diseases, Disorders & Medical Disciplines | $10.8M | 6 |
| ELGIN ACADEMY | Elgin | B24Z Education | $10.8M | 2 |
| CHICAGO PAINTERS AND | Darien | Y43 Mutual & Membership Benefit | $10.8M | 4 |
| Muslim Community Center | Chicago | X40Z Religion-Related | $10.8M | 3 |
| United States Artists Inc | Chicago | A20 Arts, Culture & Humanities | $10.7M | 4 |
| COMMUNITY PARTNERS FOR AFFORDABLE | Libertyville | P70Z Human Services | $10.7M | 4 |
| HOPE CHICAGO INC | Chicago | — | $10.7M | 6 |
| ASI | Chicago | — | $10.7M | 1 |
| LAKE VIEW TOWERS | Chicago | L20Z Housing & Shelter | $10.7M | 0 |
| FRATERNAL ORDER OF POLICE CHICAGO | Chicago | — | $10.7M | 10 |
| INTL UNION OF OPERATING ENGINEERS LOCAL | Chicago | Y43 Mutual & Membership Benefit | $10.7M | 4 |
