| Calumet College of St Joseph | Whiting | B42Z Education | $18.2M | 8 |
| SWISS VILLAGE INC | Berne | P75Z Human Services | $18.2M | 6 |
| FORT WAYNE ZOOLOGICAL SOCIETY INC | Fort Wayne | D115 Animal-Related | $18.2M | 7 |
| PORTER COUNTY COMMUNITY FOUNDATION INC | Valparaiso | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $18.1M | 4 |
| VICTORY COLLEGE PREP INC | Indianapolis | B29 Education | $18.1M | 2 |
| The Oaks Academy Inc | Indianapolis | B24 Education | $18M | 7 |
| National Federation of State High School Associations | Indianapolis | — | $18M | 10 |
| EDUCATION AT WORK INC | Indianapolis | — | $18M | 12 |
| CROSSROADS REHABILITATION CENTER INC | Indianapolis | E50Z Health Care | $17.8M | 6 |
| FULTON COUNTY REMC | Rochester | Y22 Mutual & Membership Benefit | $17.8M | 14 |
| HOLY CROSS VILLAGE AT NOTRE DAME | Notre Dame | — | $17.7M | 3 |
| KOSCIUSKO COUNTY COMMUNITY | Warsaw | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $17.7M | 1 |
| VISITING NURSE & HOSPICE HOME INC | Fort Wayne | E91Z Health Care | $17.7M | 7 |
| UNITED ASSOCIATION OF JOURNEYMEN | Indianapolis | — | $17.7M | 20 |
| WABASH CENTER INC | Lafayette | P200 Human Services | $17.5M | 2 |
| Indiana Legal Services Inc | Indianapolis | I80 Crime & Legal-Related | $17.3M | 2 |
| THE CENTER FOR HOSPICE & PALLIATIVE CARE | Mishawaka | P74 Human Services | $17.3M | 9 |
| PURDUE POLYTECHNIC HIGH SCHOOL OF INDIAN | Indianapolis | B29 Education | $17.3M | 6 |
| PUTNAM COUNTY COMPREHENSIVE SERVICES INC | Greencastle | P20Z Human Services | $17.3M | 0 |
| BEST ONE TIRE O-K-T EMPLOYEES' BENEFICIARY TRUST AGREEMENT | Monroe | Y43 Mutual & Membership Benefit | $17.2M | 0 |
| AGING AND IN-HOME SERVICES OF | Fort Wayne | P81Z Human Services | $17.2M | 2 |
| INSIDE TRACK INC | Indianapolis | — | $17.1M | 15 |
| Noble Inc | Indianapolis | P82Z Human Services | $17.1M | 2 |
| NATCO CREDIT UNION | Richmond | W61 Public & Societal Benefit | $17.1M | 2 |
| COMMUNITY ACTION PROGRAM OF | Evansville | P20Z Human Services | $17M | 3 |
| WOMEN'S CARE CENTER INC | South Bend | E400 Health Care | $16.9M | 4 |
| Bashor Home of The United | Goshen | P300 Human Services | $16.9M | 3 |
| SAGAMORE INSTITUTE INC | Indianapolis | W05 Public & Societal Benefit | $16.8M | 8 |
| PALADIN INC | Michigan City | P820 Human Services | $16.8M | 1 |
| Kiwanis International Inc | Indianapolis | — | $16.7M | 17 |
| GOLDEN YEARS HOMESTEAD INC | Fort Wayne | E91Z Health Care | $16.7M | 0 |
| GEO PREP ACADEMY OF GREATER BATON ROUGE | Indianapolis | B29 Education | $16.7M | 0 |
| HVAF OF INDIANA INC | Indianapolis | L41 Housing & Shelter | $16.7M | 3 |
| American Legion Charities Inc | Indianapolis | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $16.6M | 3 |
| YOUNG MEN'S CHRISTIAN ASSOCIATION OF SOUTHWESTERN INDIANA INC | Evansville | P27Z Human Services | $16.6M | 5 |
| ALPHA CHI OMEGA FRATERNITY INC | Indianapolis | — | $16.6M | 6 |
| THE CENTER OF WORKFORCE INNOVATIONS INC | Valparaiso | S31 Community Improvement & Capacity Building | $16.5M | 4 |
| HILLS INSURANCE COMPANY INC | Mishawaka | Y200 Mutual & Membership Benefit | $16.5M | 4 |
| RIVER HERITAGE CONSERVANCY INC | Jeffersonville | N03 Recreation & Sports | $16.5M | 3 |
| AHEPA AFFORDABLE HOUSING MANAGEMENT | Fishers | L800 Housing & Shelter | $16.5M | 6 |
| Tindley Accelerated Schools Inc | Indianapolis | B29 Education | $16.5M | 5 |
| COMMUNITY FOUNDATION OF WABASH | North Manchester | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $16.4M | 1 |
| PRAIRIE LANDING COMMUNITY INC | Indianapolis | L22 Housing & Shelter | $16.4M | 7 |
| VISIT INDY INC | Indianapolis | — | $16.4M | 11 |
| EDGEWATER SYSTEMS FOR BALANCED | Gary | F300 Mental Health & Crisis Intervention | $16.3M | 7 |
| CAREER ACADEMY OF SOUTH BEND INC | South Bend | B29 Education | $16.3M | 1 |
| CAMERON MEDICAL OUTREACH INC | Angola | E990 Health Care | $16.2M | 4 |
| INDIANA STATE UNIVERSITY FOUNDATION INC | Terre Haute | B110 Education | $16.1M | 5 |
| ST CLAIR DARDEN HEALTH SYSTEM | South Bend | E91Z Health Care | $16.1M | 8 |
| GALAXY CHARITABLE FOUNDATION INC | Indianapolis | B12 Education | $16.1M | 4 |
