| CHARTER FOR CHARITY INC | Dallas | E62 Health Care | $22.7M | 0 |
| TEXOMA COMMUNITY CREDIT UNION | Wichita Falls | — | $22.7M | 10 |
| Houston Arts Alliance | Houston | A260 Arts, Culture & Humanities | $22.7M | 5 |
| Union Gospel Mission of Tarrant County | Fort Worth | — | $22.7M | 7 |
| COMMUNITIES IN SCHOOLS OF CENTRAL TEXAS | Austin | B032 Education | $22.7M | 5 |
| ALCUIN SCHOOL | Dallas | B200 Education | $22.6M | 7 |
| SW TEXAS HOUSING SERVICE RES INC | Tomball | L80 Housing & Shelter | $22.6M | 0 |
| Pioneer Bible Translators | Dallas | X20 Religion-Related | $22.6M | 11 |
| Dairy Max Inc | Grand Prairie | — | $22.6M | 25 |
| The USAA Foundation Inc | San Antonio | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $22.6M | 0 |
| AMERICAN GI FORUM NATIONAL VETERANS OUTREACH PROGRAM INC | San Antonio | — | $22.5M | 0 |
| HOUSING BENEFITS PLAN CO JOHN POPE HOUSING SOLUTIONS ALLIANCE | Dallas | — | $22.5M | 0 |
| Paso del Norte Community Foundation | El Paso | E70 Health Care | $22.5M | 5 |
| PERRY AND JOYCE JOHNS FOUNDATION | Fort Worth | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $22.5M | 0 |
| TYLER FAMILY CIRCLE OF CARE | Tyler | E300 Health Care | $22.4M | 9 |
| AMERICAN RELIGIOUS TOWN HALL MEETING | Dallas | E91Z Health Care | $22.3M | 15 |
| HOPE HOSPICE | New Braunfels | P74Z Human Services | $22.3M | 7 |
| BOTANICAL RESEARCH INSTITUTE OF TEXAS | Fort Worth | U50 Science & Technology | $22.3M | 5 |
| ALL CHURCH HOME FOR CHILDREN FOUNDATION | Fort Worth | P117 Human Services | $22.3M | 2 |
| TIDEWATER AND BIG BEND FOUNDATION | Houston | A80 Arts, Culture & Humanities | $22.2M | 9 |
| Planned Parenthood Gulf Coast Inc | Houston | E420 Health Care | $22.2M | 12 |
| Promotional Products Association Int'l | Irving | — | $22.2M | 12 |
| COMMUNITIES IN SCHOOLS OF HOUSTON INC | Houston | B94 Education | $22.1M | 4 |
| CHRISTUS HEALTH PLAN LOUISIANA | Irving | — | $22.1M | 13 |
| LOUISIANA CLINICAL SERVICES INC | Austin | — | $22.1M | 0 |
| ROBOTICS EDUCATION & COMPETITION | Greenville | B99 Education | $22.1M | 1 |
| Mobility Credit Union | Irving | — | $22.1M | 7 |
| COMMUNITY HEALTH DEVELOPMENT INC | Uvalde | E320 Health Care | $22.1M | 13 |
| LIFTFUND INC | San Antonio | S43 Community Improvement & Capacity Building | $22.1M | 6 |
| AMERICAS CREDIT UNION | Garland | — | $22M | 14 |
| The Urban Alternative | DeSoto | X800 Religion-Related | $22M | 6 |
| THE COMMEMORATIVE AIR FORCE | Dallas | A50 Arts, Culture & Humanities | $22M | 7 |
| LTTS CHARTER SCHOOL INC | Irving | B20P Education | $22M | 5 |
| RESOURCE CENTER OF DALLAS INC | Dallas | G81Z Diseases, Disorders & Medical Disciplines | $21.9M | 6 |
| UNITED TEXAS CREDIT UNION | San Antonio | — | $21.9M | 11 |
| PEDIATRIC HEALTH MANAGEMENT SERVICES | Dallas | — | $21.9M | 11 |
| LAKESIDE COUNTRY CLUB | Houston | — | $21.8M | 8 |
| COMMISSION TO EVERY NATION | Kerrville | X20 Religion-Related | $21.8M | 3 |
| THE CITIZENS FOUNDATION USA | Houston | P12 Human Services | $21.7M | 3 |
| MUNICIPAL GOLF ASSOCIATION - SA | San Antonio | N6A Recreation & Sports | $21.7M | 5 |
| ABILENE GOODWILL INDUSTRIES INC | Abilene | J32Z Employment | $21.6M | 3 |
| ORENDA EDUCATION | Georgetown | F20 Mental Health & Crisis Intervention | $21.6M | 3 |
| 15TH STREET FOUNDATION | Dallas | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $21.6M | 0 |
| TRINITY BROADCASTING OF FLORIDA | Fort Worth | X840 Religion-Related | $21.5M | 10 |
| Trustees of Shannon West Texas Memorial Hospital | San Angelo | E110 Health Care | $21.5M | 8 |
| COMMUNITIES IN SCHOOLS OF SAN ANTONIO | San Antonio | B95Z Education | $21.4M | 2 |
| AUSTIN HABITAT FOR HUMANITY INC | Austin | — | $21.4M | 10 |
| The Wildcat Foundation | Fort Worth | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $21.4M | 0 |
| HOUSTON LIVESTOCK SHOW AND RODEO | Houston | N520 Recreation & Sports | $21.3M | 3 |
| SAN ANTONIO METROPOLITAN MINISTRIES INC | San Antonio | — | $21.3M | 5 |
