| CITIZENS MEMORIAL HEALTH CARE FOUNDATION | Bolivar | E91Z Health Care | $75.2M | 12 |
| THE RANKEN-JORDAN HOME FOR CONVALESCENT CRIPPLED CHILDREN | Maryland Heights | E91Z Health Care | $75.2M | 9 |
| TEAMSTERS & EMPLOYERS WELFARE TRUST OF ILLINOIS | Earth City | — | $75.1M | 0 |
| Ascension Medical Group Michigan | St Louis | E32 Health Care | $74.8M | 22 |
| COLUMBIA COLLEGE | Columbia | B430 Education | $74.1M | 16 |
| International Academy of Science | Kansas City | — | $73.9M | 3 |
| THE CRAWFORD TAYLOR FOUNDATION | St Louis | T20Z Philanthropy, Voluntarism & Grantmaking Foundations | $72.6M | 0 |
| Providence Health Alliance | St Louis | E30 Health Care | $72.5M | 20 |
| Platte-Clay Electric Cooperative Inc | Kearney | — | $72.2M | 15 |
| Saint Lukes Health System Home Care and Hospice | Kansas City | E21 Health Care | $71.9M | 14 |
| Alexian Brothers Specialty Group | St Louis | E31 Health Care | $71.5M | 6 |
| WELFARE FUND OF ENGINEERS LOCAL UNION 513 | Bridgeton | — | $71.3M | 0 |
| COX-MONETT HOSPITAL INC | Monett | E22 Health Care | $71M | 11 |
| Evangel University | Springfield | B420 Education | $70M | 5 |
| MERCY HEALTH SOUTHWEST MISSOURIKANSAS COMMUNITIES | Joplin | — | $69.8M | 15 |
| INTERNATIONAL ASSOC OF MACHINISTS AND AEROSPACE WORKERS WELFARE TRUST | Bridgeton | — | $69.8M | 0 |
| Mary Institute and St Louis Country Day School | St Louis | B200 Education | $69.3M | 7 |
| ASCENSION VIA CHRISTI HOSPITAL PITTSBURG INC | St Louis | E220 Health Care | $69.1M | 11 |
| Saint Luke's Hospital of Chillicothe | Chillicothe | E21 Health Care | $69M | 16 |
| BOARD OF TRUSTEES GREATER ST LOUIS CONSTRUCTION LABORERS WELFARE FUND | St Louis | — | $67.1M | 3 |
| PRESENCE SENIOR SERVICES CHICAGOLAND | St Louis | E910 Health Care | $67.1M | 14 |
| INTERCOUNTY ELECTRIC COOPERATIVE ASSOCIATION | Licking | — | $66.8M | 15 |
| ALPHAPOINTE | Kansas City | J33 Employment | $66.5M | 8 |
| CAMERON REGIONAL MEDICAL CENTER | Cameron | E220 Health Care | $65.2M | 11 |
| CARDINAL GLENNON CHILDREN'S FOUNDATION | St Louis | — | $65.1M | 6 |
| Missouri Baptist University | St Louis | B420 Education | $64.3M | 12 |
| DONALD DANFORTH PLANT SCIENCE CENTER | Saint Louis | U500 Science & Technology | $63.8M | 13 |
| JOHN FITZGIBBON MEMORIAL HOSPITAL | Marshall | E220 Health Care | $62.9M | 9 |
| AVILA UNIVERSITY | Kansas City | B43Z Education | $62.8M | 9 |
| FRIENDSHIP VILLAGE OF SOUTH COUNTY | St Louis | P750 Human Services | $61.5M | 9 |
| OPERATING ENGINEERS LOCAL 101 HEALTH AND WELFARE PLAN | Kansas City | — | $61.1M | 2 |
| Providence Hospital | St Louis | E220 Health Care | $61M | 13 |
| MERCY HOSPITAL LINCOLN | Troy | E22 Health Care | $60.6M | 13 |
| INTERNATIONAL BROTHERHOOD OF BOILERMAKERS IRON SHIP BUILDERS | Kansas City | — | $60.3M | 15 |
| Cox Health Systems HMO Inc | Springfield | E21 Health Care | $60.3M | 12 |
| Ozark Center | Joplin | F31Z Mental Health & Crisis Intervention | $60.1M | 11 |
| Herzog Foundation Resource Management | Smithville | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $60M | 10 |
| BETHESDA LONG TERM CARE INC | St Louis | E910 Health Care | $59.9M | 14 |
| INTERNATIONAL BROTHERHOOD OF ELETRL WORKERS HLTH & WLFR FND LOCAL 124 | Kansas City | — | $59.6M | 0 |
| Center for Human Services Inc | Sedalia | — | $58.7M | 7 |
| THE SAINT LOUIS ZOO ASSOCIATION | Saint Louis | D115 Animal-Related | $58.5M | 10 |
| CONSORTIUM FOR GRADUATE STUDY IN MANAGEMENT | Chesterfield | — | $58M | 4 |
| COMMUNITY FOUNDATION OF THE OZARKS INC | Springfield | T310 Philanthropy, Voluntarism & Grantmaking Foundations | $57.7M | 4 |
| CORNERSTONES OF CARE | Kansas City | P19 Human Services | $57.5M | 6 |
| LEONARD & BERYL BUCK FOUNDATION C/O WELLS FARGO BANK | Saint Louis | T900 Philanthropy, Voluntarism & Grantmaking Foundations | $57.4M | 0 |
| GOODWILL OF WESTERN MISSOURI & EASTERN KANSAS | Kansas City | J320 Employment | $57.2M | 8 |
| UNITED FOOD AND COMMERCIAL WORKERS UNION LOCAL NO 655 WELFARE FUND | Ballwin | — | $57.1M | 0 |
| CONFLUENCE ACADEMY | St Louis | B20 Education | $57.1M | 7 |
| Missouri Hospital Plan | Jefferson City | — | $56.7M | 7 |
| ASCENSION VIA CHRISTI HOSPITAL ST TERESA INC | St Louis | E22 Health Care | $56.4M | 14 |
