| SERVICE EMPLOYEES INTERNATIONAL | Salem | — | $10.9M | 21 |
| Green Building Initiative Inc | Portland | C35 Environment | $10.9M | 6 |
| DOUGLAS FOREST PROTECTIVE ASSOCIATION | Roseburg | — | $10.9M | 1 |
| NETWORK FOR OREGON AFFORDABLE HOUSING | Portland | L200 Housing & Shelter | $10.9M | 6 |
| LEGACY VISITING NURSE ASSOCIATION | Tualatin | E032 Health Care | $10.8M | 25 |
| COLUMBIA RIVER MARITIME MUSEUM | Astoria | A500 Arts, Culture & Humanities | $10.8M | 3 |
| SERVICE EMPLOYEES INTL UNION LOCAL | Portland | — | $10.7M | 36 |
| ST MARY'S HOME | Beaverton | P730 Human Services | $10.7M | 3 |
| LAUREL HILL CENTER | Eugene | F33Z Mental Health & Crisis Intervention | $10.7M | 1 |
| THE OREGON ZOO FOUNDATION | Portland | D115 Animal-Related | $10.7M | 5 |
| SOUTHERN OREGON ASPIRE | Grants Pass | J300 Employment | $10.7M | 2 |
| AGRICULTURAL RESEARCH FOUNDATION | Corvallis | — | $10.6M | 4 |
| PORTLAND BUSINESS ALLIANCE | Portland | S41 Community Improvement & Capacity Building | $10.6M | 6 |
| PERSONALIZED LEARNING INC | Redmond | B29 Education | $10.6M | 3 |
| OPPORTUNITY FOUNDATION OF CENTRAL OREGON | Redmond | P820 Human Services | $10.5M | 5 |
| Hollis Foundation | Portland | T11 Philanthropy, Voluntarism & Grantmaking Foundations | $10.5M | 3 |
| OREGON FOR QUALITY VIRTUAL EDUCATIO | Prairie City | B29 Education | $10.5M | 0 |
| OREGON BALLET THEATRE | Portland | A63 Arts, Culture & Humanities | $10.5M | 3 |
| THISTLE & NEST | Bend | L20 Housing & Shelter | $10.5M | 0 |
| KLAMATH FAMILY HEAD START | Klamath Falls | B22Z Education | $10.4M | 2 |
| JOIN | Portland | P28Z Human Services | $10.4M | 5 |
| OCF Joseph E Weston Public Foundation | Portland | T11 Philanthropy, Voluntarism & Grantmaking Foundations | $10.4M | 3 |
| THE SALEM FOUNDATION | Salem | T31Z Philanthropy, Voluntarism & Grantmaking Foundations | $10.4M | 1 |
| WAVERLEY COUNTRY CLUB | Portland | — | $10.3M | 5 |
| Marcia H Randall Foundation | Lake Oswego | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $10.3M | 0 |
| ONPOINT COMMUNITY CREDIT UNION | Portland | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $10.3M | 0 |
| PLANNED PARENTHOOD OF SW OREGON | Eugene | E420 Health Care | $10.3M | 8 |
| THE CONTINGENT | Portland | S20 Community Improvement & Capacity Building | $10.1M | 8 |
| PORTLAND VA RESEARCH FOUNDATION | Portland | U50Z Science & Technology | $10.1M | 6 |
| THE NEXT DOOR INC | Hood River | I44Z Crime & Legal-Related | $10.1M | 3 |
| UMPQUA HOMES INC | Roseburg | — | $10.1M | 1 |
| TILLAMOOK FAMILY COUNSELING CENTER | Tillamook | P820 Human Services | $10.1M | 1 |
| SILVIES RIVER CHARTER SCHOOL | Crane | B19 Education | $10.1M | 0 |
| BIENESTAR INC | Hillsboro | L200 Housing & Shelter | $10M | 5 |
| ECOTRUST | Portland | Z99Z Unknown | $9.9M | 13 |
| G Street Integrated Health | Springfield | E30 Health Care | $9.9M | 6 |
| EL PROGRAMA HISPANO CATOLICO | Gresham | P20 Human Services | $9.8M | 2 |
| MID-COLUMBIA CHILDRENS COUNCIL INC | Hood River | B22Z Education | $9.8M | 2 |
| ROOFERS LOCAL 49 WELFARE FUND | Portland | — | $9.8M | 0 |
| THE ANJULICIA FOUNDATION | Bend | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $9.8M | 0 |
| WASCO COUNTY NURSING CARE INC | The Dalles | E91 Health Care | $9.8M | 7 |
| NORTHWEST REGIONAL RE-ENTRY CENTER | Portland | I31Z Crime & Legal-Related | $9.7M | 4 |
| DYNAMIC LIFE INC | Keizer | X20 Religion-Related | $9.7M | 2 |
| LIVING OPPORTUNITIES INC | Medford | J30Z Employment | $9.7M | 2 |
| MULTNOMAH DEFENDERS INC | Portland | M40 Public Safety, Disaster Preparedness & Relief | $9.6M | 6 |
| EARTH ADVANTAGE | Portland | L81 Housing & Shelter | $9.6M | 5 |
| OSLC DEVELOPMENTS INC | Eugene | V112 Social Science | $9.6M | 5 |
| 211INFO | Portland | F40Z Mental Health & Crisis Intervention | $9.6M | 1 |
| HOUSECALL PROVIDERS PC | Portland | G03 Diseases, Disorders & Medical Disciplines | $9.6M | 9 |
| GRACE CASCADE CHRISTIAN SCHOOLS | Medford | — | $9.6M | 2 |
