| WASHINGTON COUNTY JOHNSON CITY | Johnson City | E63Z Health Care | $16.5M | 3 |
| TENNESSEE HEALTH FOUNDATION INC | Chattanooga | T21 Philanthropy, Voluntarism & Grantmaking Foundations | $16.5M | 0 |
| CROWN POINT CHRISTIAN VILLAGE | Nashville | E910 Health Care | $16.4M | 4 |
| NISWONGER FOUNDATION INC | Greeneville | B21 Education | $16.3M | 2 |
| RURAL MEDICAL SERVICES INC | Newport | — | $16.3M | 11 |
| ISAIAH 117 HOUSE | Elizabethton | P32 Human Services | $16.3M | 2 |
| Jacksonville Plumbers & Pipefitters Health & Welfare Fund | Goodlettsville | — | $16.3M | 0 |
| GENERATIONS HEALTH ASSOCIATION INC | McMinnville | E60Z Health Care | $16.3M | 10 |
| FIRST TENNESSEE HUMAN RESOURCE AGENCY | Johnson City | P200 Human Services | $16.3M | 1 |
| LAKESHORE PARK CONSERVANCY | Knoxville | N32 Recreation & Sports | $16.2M | 0 |
| SHEET METAL WORKERS LOCAL 85 | Goodlettsville | — | $16M | 0 |
| Goodwill Industries of Tenneva Area Inc | Kingsport | — | $16M | 1 |
| MICHAEL DUNN CENTER | Kingston | P820 Human Services | $16M | 0 |
| BOYD BUCHANAN SCHOOL | Chattanooga | B200 Education | $15.8M | 2 |
| THE HCA HOPE FUND | Nashville | P60 Human Services | $15.8M | 0 |
| MEDICAL EDUCATION & RESEARCH INSTITUTE | Memphis | B54Z Education | $15.6M | 7 |
| INTREPID COLLEGE PREPARATORY SCHOOL | Antioch | B29 Education | $15.5M | 3 |
| JEWISH FOUNDATION OF MEMPHIS | Memphis | X113 Religion-Related | $15.5M | 0 |
| LEWIS MEMORIAL CHRISTIAN VILLAGE | Nashville | — | $15.5M | 4 |
| TENNESSEE STATE COLLABORATIVE ON | Nashville | B80 Education | $15.5M | 11 |
| HERBERT A FRITCH FAMILY FOUNDATION | Nashville | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $15.4M | 0 |
| MERCY HEALTH SERVICES INC | Franklin | E20 Health Care | $15.4M | 10 |
| BMG FAMILY PHYSICIANS GROUP FOUNDATION | Memphis | E30 Health Care | $15.4M | 19 |
| HASLAM FAMILY FOUNDATION INC | Knoxville | T22Z Philanthropy, Voluntarism & Grantmaking Foundations | $15.3M | 0 |
| Kingsway Charities Inc | Bristol | Q300 International, Foreign Affairs & National Security | $15.3M | 2 |
| DONELSON CHRISTIAN ACADEMY INC | Nashville | B200 Education | $15.3M | 4 |
| Christian Schools Inc | Madison | — | $15.3M | 1 |
| SHEET METAL WORKERS LOCAL NO 110 | Goodletsville | — | $15.2M | 0 |
| The Urban Child Institute | Memphis | — | $15.2M | 7 |
| POSITIVELY LIVING | Knoxville | P33 Human Services | $15.2M | 1 |
| LEGAL AID SOCIETY OF MIDDLE TENNESSEE | Nashville | — | $15.1M | 7 |
| PROGRESSIVE HEALTHCARE PROVIDERS | Collierville | — | $15.1M | 0 |
| ACCELERATE - THE NATIONAL COLLABORATIVE | Nashville | B05 Education | $15M | 8 |
| YOUNG MEN'S CHRISTIAN ASSOCIATION | Knoxville | P27Z Human Services | $14.9M | 2 |
| COUNCIL FOR ALCOHOL & DRUG ABUSE | Chattanooga | F20Z Mental Health & Crisis Intervention | $14.8M | 3 |
| CHICKASAW ELECTRIC COOPERATIVE INC | Somerville | — | $14.8M | 17 |
| Wellmont Hawkins County Memorial | Johnson City | E22 Health Care | $14.8M | 14 |
| FAMILY RESOURCE AGENCY OF NORTH | Cleveland | — | $14.7M | 2 |
| THE MARTIN FAMILY FOUNDATION INC | Memphis | T11 Philanthropy, Voluntarism & Grantmaking Foundations | $14.6M | 4 |
| WETLANDS AMERICA TRUST INC | Memphis | C110 Environment | $14.6M | 5 |
| Developmental Services of Dickson County | Dickson | P700 Human Services | $14.6M | 1 |
| SERTOMA CENTER INC | Knoxville | — | $14.6M | 1 |
| UNITED WAY OF GREATER KNOXVILLEINC | Knoxville | — | $14.6M | 2 |
| CHOTA COMMUNITY HEALTH SERVICES | Madisonville | E70 Health Care | $14.5M | 10 |
| HICKORY POINT CHRISTIAN VILLAGE INC | Nashville | — | $14.5M | 4 |
| RUTHERFORD COUNTY PRIMARY CARE CLINIC INC | Murfreesboro | E32I Health Care | $14.5M | 10 |
| OAK HILL SCHOOL | Nashville | — | $14.5M | 8 |
| AMERICAN ECONOMIC ASSOCIATION | Nashville | V030 Social Science | $14.3M | 14 |
| W&H FOUNDATION | Knoxville | — | $14.3M | 0 |
| Housing Affordability Trust | Nashville | L12 Housing & Shelter | $14.3M | 1 |
