| Grant Rehabilitation and Care Center Inc | Petersburg | P75 Human Services | $12.2M | 2 |
| TUG RIVER HEALTH ASSOCIATION INC | Gary | E32 Health Care | $12.1M | 9 |
| PARKERSBURG AREA COMMUNITY FOUNDATION INC (PREVIOUSLY PACF INC) | Parkersburg | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $12M | 1 |
| FIRST CHOICE SERVICES INC | Charleston | F20 Mental Health & Crisis Intervention | $11.9M | 2 |
| COALFIELD COMMUNITY ACTION PARTNERSHIP | Williamson | S200 Community Improvement & Capacity Building | $11.7M | 2 |
| West Virginia University Dental Corporation | Morgantown | B52Z Education | $11.4M | 12 |
| COMMUNITY FOUNDATION FOR THE OHIO VALLEY INC | Wheeling | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $11.3M | 1 |
| HOSPICE CARE CORPORATION D/B/A WEST VIRGINIA CARING | Arthurdale | — | $11.2M | 4 |
| GOODWILL INDUSTRIES KYOWVA AREA INC | Huntington | J32 Employment | $10.7M | 2 |
| HAZEL RUBY MCQUAIN CHARITABLE TRUST | Morgantown | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $10.6M | 0 |
| West Virginia School of Osteopathic Medicine Clinic Inc | Lewisburg | — | $10.4M | 8 |
| KVC BEHAVIORAL HEALTHCARE WEST VIRGINIA INC | Charleston | E21 Health Care | $10.4M | 8 |
| JOB SQUAD INC | Bridgeport | J200 Employment | $10.1M | 2 |
| CATHOLIC CHARITIES WEST VIRGINIA INC | Wheeling | P200 Human Services | $9.9M | 7 |
| EASTERN PANHANDLE MENTAL HEALTH CENTERINC | Martinsburg | F32Z Mental Health & Crisis Intervention | $9.8M | 12 |
| INTERNATIONAL BROTHERHOOD OF ELECTRICAL WORKERS UNION 480JACKSON | Ona | — | $9.8M | 5 |
| BECKLEY AREA FOUNDATION INC | Beckley | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $9.4M | 2 |
| Appalachian Bible College Inc | Mount Hope | — | $9.3M | 3 |
| CONCORD UNIVERSITY FOUNDATION INC | Athens | B110 Education | $9.3M | 0 |
| CHAMBER ASSOCIATION BENEFIT PLAN TRUST | Wheeling | Y43 Mutual & Membership Benefit | $9.2M | 1 |
| PLAYMATES PRE-SCHOOL AND CHILD-CARE CENTERS INC | Huntington | P33 Human Services | $9.1M | 3 |
| MON HEALTH MARION NEIGHBORHOOD HOSPITAL INC | Morgantown | E22 Health Care | $9M | 6 |
| APPALACHIAN AREA AGENCY ON AGING | Princeton | P81Z Human Services | $9M | 2 |
| Potomac Comprehensive Diagnostic & Guidance Center Inc Potomac Center | Romney | E50Z Health Care | $9M | 4 |
| EMS INC | Elkins | — | $8.9M | 3 |
| AFL-CIO APPALACHIAN COUNCIL INC | Charleston | — | $8.9M | 3 |
| DIGNITY HOSPICE OF SOUTHERN WV INC | Chapmanville | E24Z Health Care | $8.7M | 7 |
| PACE ENTERPRISES OF WEST VIRGINIA | Morgantown | J300 Employment | $8.6M | 1 |
| NORTHERN PANHANDLE HEADSTART INC | Wheeling | B22Z Education | $8.6M | 0 |
| POLYMER ALLIANCE ZONE INC | Davisville | S30 Community Improvement & Capacity Building | $8.5M | 2 |
| HEALTHWAYS INC | Weirton | F320 Mental Health & Crisis Intervention | $8.5M | 0 |
| WEST VIRGINIA PRIMARY CARE ASSOCIATION INC | Charleston | — | $8.4M | 2 |
| CLARA WELTY TESTAMENTARY TRUST (WELTY HOME FOR THE AGED INC BENEFICIARY) | Wheeling | — | $8.4M | 1 |
| International Union of Operating Engineers Local 132 | Charleston | — | $8.4M | 11 |
| FLORENCE CRITTENTON PROGRAMS INC | Wheeling | P700 Human Services | $8.1M | 1 |
| KEITH ALBEE PERFORMING ARTS CENTER INC | Huntington | A65 Arts, Culture & Humanities | $8M | 1 |
| Plumbers & Pipefitters Local 625 Health & Welfare Fund | Charleston | Y43 Mutual & Membership Benefit | $7.9M | 2 |
| RALEIGH COUNTY COMMISSION ON AGING INC | Beckley | P81 Human Services | $7.7M | 3 |
| BIG GREEN SCHOLARSHIP FOUNDATION | Huntington | — | $7.7M | 0 |
| ST BARBARA'S MEMORIAL NURSING HOME | Monongah | — | $7.6M | 1 |
| MARSHALL UNIVERSITY REAL ESTATE FOUNDATION INC | Huntington | B11 Education | $7.6M | 1 |
| PENDLETON COMMUNITY CARE INC | Franklin | E39Z Health Care | $7.5M | 8 |
| Mountain State Learning Solutions | Charleston | B29 Education | $7.5M | 0 |
| PUTNAM COUNTY AGING PROGRAM INC | Saint Albans | — | $7.5M | 1 |
| PRIDE COMMUNITY SERVICES INC | Logan | S32Z Community Improvement & Capacity Building | $7.3M | 2 |
| MON ELDER SERVICES INC | Morgantown | L220 Housing & Shelter | $7.1M | 4 |
| WEST VIRGINIA COALITION TO END HOMELESSNESS INCORPORATED | Bridgeport | P85 Human Services | $7M | 2 |
| LINCOLN COUNTY OPPORTUNITY COMPANY | Hamlin | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $6.8M | 4 |
| WV PERINATAL PARTNERSHIP INC | Charleston | E99 Health Care | $6.8M | 3 |
| INTERNATIONAL BROTHERHOOD OF ELECTRICAL WORKERS LU #317 | Huntington | — | $6.7M | 11 |
