| THE GOOD SHEPHERD HOME LONG-TERM CARE FACILITY INC | Allentown | P730 Human Services | $31.5M | 11 |
| CAIRN UNIVERSITY | Langhorne | B500 Education | $31.5M | 5 |
| KIDSPEACE CHILDREN'S HOSPITAL | Schnecksville | — | $31.4M | 8 |
| CLAVERACK RURAL ELECTRIC COOPERATIVE | Wysox | — | $31.4M | 17 |
| Presbyterian SeniorCare | Oakmont | P750 Human Services | $31.3M | 11 |
| ARCONIC FOUNDATION | Pittsburgh | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $31.2M | 0 |
| FAMILY FIRST HEALTH CORPORATION | York | E320 Health Care | $31.1M | 10 |
| ONCOLOGY NURSING SOCIETY | Pittsburgh | — | $31.1M | 10 |
| ASPIRA INC OF PENNSYLVANIA | Philadelphia | — | $31M | 5 |
| BUTLER COUNTY CHILDREN'S CENTER INC DBA EARLY LEARNING CONNECTIONS | Butler | P33Z Human Services | $31M | 3 |
| RONALD MCDONALD HOUSE CHARITIES OF THE PHILADELPHIA REGION | Philadelphia | — | $30.6M | 6 |
| COMMUNITY FOUNDATION OF GREATER JOHNSTOWN | Johnstown | T31Z Philanthropy, Voluntarism & Grantmaking Foundations | $30.5M | 2 |
| MASTERY CHARTER SCHOOL - THOMAS CAMPUS | Philadelphia | B29 Education | $30.5M | 7 |
| ZOOLOGICAL SOCIETY OF PITTSBURGH | Pittsburgh | D500 Animal-Related | $30.5M | 7 |
| LYCOMING-CLINTON COUNTIES COMM FOR COMMUNITY ACTION (STEP) INC | Williamsport | P200 Human Services | $30.5M | 4 |
| CORRY MEMORIAL HOSPITAL ASSOCIATION | Corry | E220 Health Care | $30.3M | 12 |
| PENN FOUNDATION INC | Sellersville | F80Z Mental Health & Crisis Intervention | $30.3M | 3 |
| FOLIUM INC | Chambersburg | — | $30.3M | 7 |
| ALEXS LEMONADE STAND FOUNDATION | Wynnewood | — | $30.2M | 7 |
| WINCHESTER THURSTON SCHOOL | Pittsburgh | — | $30.2M | 5 |
| WYOMING SEMINARY COLLEGE PREPARATORY SCHOOL | Kingston | B20 Education | $30.2M | 5 |
| CARING HEART REHABILITATION AND NURSING CENTER INC | Philadelphia | E91 Health Care | $30.1M | 6 |
| YOUNG MEN'S CHRISTIAN ASSOCIATION OF GREATER PITTSBURGH | Pittsburgh | P270 Human Services | $30.1M | 6 |
| HARDY WILLIAMS ACADEMY CHARTER SCHOOL | Philadelphia | B29 Education | $30.1M | 7 |
| BENEFIT FUND FOR HOSPITAL AND HEALTH CARE EMPLOYEES PHILADELPHIA AND VICINITY | Philadelphia | — | $30.1M | 6 |
| ZACHARY SMITH REYNOLDS TRUST | Pittsburgh | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $30.1M | 1 |
| COMMUNITY ACTION PARTNERSHIP OF LANCASTER COUNTY INC | Lancaster | P200 Human Services | $30.1M | 6 |
| ST PAUL HOMES | Greenville | P750 Human Services | $30M | 1 |
| SENECA PLACE | Pittsburgh | E20 Health Care | $29.8M | 10 |
| SERGE GLOBAL INC | Jenkintown | — | $29.8M | 8 |
| HOMESTEAD VILLAGE INC | Lancaster | P750 Human Services | $29.7M | 5 |
| Pacific Gas & Electric Long-Term Disability Trust For Union Empl | Pittsburgh | — | $29.6M | 1 |
| PLUMBERS LOCAL UNION NO 690 HEALTH PLAN | Philadelphia | — | $29.6M | 7 |
| ALLIED SERVICES INSTITUTE OF REHABILITATION MEDICINE | Clarks Summit | E240 Health Care | $29.6M | 7 |
| PLEASANT RIDGE MANOR | Girard | E90Z Health Care | $29.5M | 4 |
| HERITAGE VALLEY HEALTH SYSTEMINC | Beaver | E210 Health Care | $29.4M | 4 |
| BARC DEVELOPMENTAL SERVICES INC | Holicong | — | $29.2M | 7 |
| FAMILY HEALTH COUNCIL OF CENTRAL PA INC | Camp Hill | E42Z Health Care | $29.2M | 2 |
| PLEASANT VIEW RETIREMENT COMMUNITY | Manheim | P750 Human Services | $29.2M | 4 |
| MAINSTAY LIFE SERVICES | Pittsburgh | L200 Housing & Shelter | $29.2M | 5 |
| Quarryville Presbyterian Retirement Community | Quarryville | P750 Human Services | $29.1M | 10 |
| YOUNG MEN AND WOMEN'S HEBREW ASSOCIATION AND IRENE KAUFMANN CENT | Pittsburgh | P270 Human Services | $29.1M | 7 |
| THE BALDWIN SCHOOL | Bryn Mawr | B200 Education | $29.1M | 7 |
| ALLIED SERVICES PERSONAL CARE INC | Clarks Summit | L22 Housing & Shelter | $29M | 5 |
| Butler Cancer Associates Inc | Pittsburgh | G30 Diseases, Disorders & Medical Disciplines | $29M | 0 |
| MASTERY CHARTER SCHOOL - GRATZ CAMPUS | Philadelphia | B29 Education | $29M | 7 |
| PENN MEDICINE-PMA | Philadelphia | E31 Health Care | $28.9M | 7 |
| PHILADELPHIA INDUSTRIAL DEVELOPMENT CORPORATION | Philadelphia | S41 Community Improvement & Capacity Building | $28.9M | 16 |
| ABINGTON FRIENDS SCHOOL | Jenkintown | B20 Education | $28.9M | 6 |
| Philadelphia Academy Charter School | Philadelphia | B20 Education | $28.7M | 7 |
