| PROFESSIONAL FOOTBALL PLAYERS' INSTRUST | New York | — | $124.9M | 0 |
| ASSOCIATION OF THE GRADUATES OF THE UNITED STATES MILITARY ACADEMY | West Point | W030 Public & Societal Benefit | $124.9M | 10 |
| THE COMMUNITY PRESERVATION CORPORATION | New York | S200 Community Improvement & Capacity Building | $124.8M | 55 |
| DUNE ROAD FOUNDATION INC | New York | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $124.3M | 0 |
| ARAB GULF PROGRAMME FOR DEVELOPMENT | New York | Q30 International, Foreign Affairs & National Security | $124.3M | 13 |
| The Wallace Foundation | New York | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $124.1M | 7 |
| NEW YORK MEDICAL COLLEGE | Valhalla | — | $123.8M | 16 |
| SVCMC INC | New York | E31 Health Care | $123.7M | 8 |
| NYSARC INC FULTON-SCHOHARIE COUNTIES CHAPTER | Johnstown | P820 Human Services | $123.2M | 8 |
| UNIVERSITY AT BUFFALO FOUNDATION INC | Buffalo | B11 Education | $123.2M | 2 |
| NEWARK-WAYNE COMMUNITY HOSPITAL | Newark | E220 Health Care | $123.1M | 13 |
| JUSTICE INNOVATION INC | New York | I50 Crime & Legal-Related | $123M | 8 |
| NATHAN LITTAUER HOSPITAL ASSOCIATION | Gloversville | E220 Health Care | $122.5M | 8 |
| B H R A G S HOMECARE INC | Brooklyn | — | $122.1M | 7 |
| THE EPOCH TIMES ASSOCIATION INC | New York | A23 Arts, Culture & Humanities | $122.1M | 2 |
| RENSSELAER COLUMBIA GREENE GROUP HEALTH INSURANCE TRUST | Castleton On Hudson | — | $122M | 0 |
| PROJECT RENEWAL INC | New York | F300 Mental Health & Crisis Intervention | $121.7M | 13 |
| REGIONAL FOOD BANK OF NORTHEASTERN NEW YORK INC | Latham | K31Z Food, Agriculture & Nutrition | $121.1M | 8 |
| COORDINATED BEHAVIORAL CARE | New York | B99 Education | $121M | 7 |
| CATHOLIC CHARITIES NEIGHBORHOOD SERVICES INC | Brooklyn | P200 Human Services | $120.7M | 13 |
| 199 PHILANTHROPIC FUND | New York | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $120.3M | 0 |
| Putnam Hospital Center | Carmel | E220 Health Care | $119.2M | 14 |
| EHS INC | Buffalo | G81Z Diseases, Disorders & Medical Disciplines | $118.8M | 10 |
| ALFRED P SLOAN FOUNDATION | New York | B82 Education | $118.4M | 15 |
| The Rogosin Institute Inc | New York | E050 Health Care | $118.4M | 31 |
| GIRL SCOUTS OF THE UNITED STATES OF AMERICA | New York | O420 Youth Development | $118.1M | 19 |
| ACCESS SUPPORTS FOR LIVING INC | Middletown | P820 Human Services | $118.1M | 16 |
| CAYUGA MEDICAL ASSOCIATES PC | Ithaca | E20 Health Care | $117.9M | 14 |
| Overdeck Family Foundation Inc | New York | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $117.9M | 2 |
| SELFHELP COMMUNITY SERVICES INC | New York | P20 Human Services | $117.9M | 14 |
| THE BREAST CANCER RESEARCH FOUNDATION INC | New York | M20Z Public Safety, Disaster Preparedness & Relief | $117.4M | 12 |
| WAGNER COLLEGE | Staten Island | B430 Education | $117M | 12 |
| WHITNEY MUSEUM OF AMERICAN ART | New York | A510 Arts, Culture & Humanities | $116.7M | 13 |
| THE PAUL E SINGER FOUNDATION | New York | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $115.9M | 2 |
| TERENCE CARDINAL COOKE HEALTH CARE CENTER | New York | E910 Health Care | $115.8M | 8 |
| AIM SERVICES INC | Saratoga Springs | P73Z Human Services | $115.8M | 9 |
| AMERICAN SOCIETY FOR TECHNION ISRAEL INSTITUTE OF TECHNOLOGY INC | New York | Q300 International, Foreign Affairs & National Security | $115.8M | 12 |
| VOCATIONAL INSTRUCTION PROJECT COMMUNITY SERVICES INC | Bronx | — | $115.5M | 7 |
| BLYTHEDALE CHILDREN'S HOSPITAL | Valhalla | E24 Health Care | $115.5M | 14 |
| HUMAN CARE SERVICES FOR FAMILIES & CHILDREN INC | Brooklyn | E920 Health Care | $115.5M | 11 |
| NEW YORK STATE TECHNOLOGY ENTERPRISE CORPORATION | Rome | Z99 Unknown | $114.9M | 21 |
| ALICE HYDE MEDICAL CENTER | Malone | E220 Health Care | $114.5M | 14 |
| PRACTISING LAW INSTITUTE | New York | B600 Education | $114.3M | 14 |
| THE PHILHARMONIC SYMPHONY SOCIETY OF NY INC | New York | A690 Arts, Culture & Humanities | $113.9M | 9 |
| THE MACMILLAN FAMILY FOUNDATION INC | New York | T21 Philanthropy, Voluntarism & Grantmaking Foundations | $113.8M | 0 |
| TED FOUNDATION INC | New York | S19 Community Improvement & Capacity Building | $113.2M | 2 |
| ADULTS AND CHILDREN WITH LEARNING AND DEVELOPMENTAL DISABILITIES INC | Bethpage | P820 Human Services | $113.1M | 9 |
| NEW YORK EYE & EAR INFIRMARY | New York | E240 Health Care | $112.6M | 21 |
| RUTLAND NURSING HOME INC | Brooklyn | E91Z Health Care | $112.5M | 11 |
| UPSTATE CEREBRAL PALSY INC | Utica | G200 Diseases, Disorders & Medical Disciplines | $112.4M | 8 |
