| THE UNIVERSITY OF VERMONT MEDICAL CENTER | Burlington | E22Z Health Care | $2.4B | 22 |
| PRESIDENT AND FELLOWS OF MIDDLEBURY COLLEGE | Middlebury | B430 Education | $520.2M | 13 |
| THE UNIVERSITY OF VERMONT HEALTH NETWORK MEDICAL GROUP INC | Burlington | E32Z Health Care | $385.4M | 27 |
| Rutland Hospital Inc | Rutland | E220 Health Care | $363.8M | 22 |
| CENTRAL VERMONT MEDICAL CENTER INC | Berlin | E220 Health Care | $319.9M | 15 |
| SOUTHWESTERN VERMONT MEDICAL CENTER | Bennington | E220 Health Care | $228.8M | 18 |
| NORWICH UNIVERSITY | Northfield | B430 Education | $198.9M | 13 |
| AREA RESOURCES FOR INDIVIDUALIZED SERVICES INC A/K/A ARIS SOLUTIONS | White River Junction | F60Z Mental Health & Crisis Intervention | $148.6M | 7 |
| CHAMPLAIN COLLEGE INCORPORATED | Burlington | B420 Education | $136.2M | 18 |
| HowardCenter Inc | Burlington | P800 Human Services | $136M | 10 |
| Northwestern Medical Center | St Albans | E220 Health Care | $136M | 8 |
| Northeastern Vermont Regional Hosp Inc | St Johnsbury | E22 Health Care | $131.6M | 10 |
| VERMONT ENERGY INVESTMENT CORPORATION | Winooski | C350 Environment | $130.9M | 22 |
| PORTER HOSPITAL INC | Middlebury | E22 Health Care | $128.6M | 14 |
| Brattleboro Memorial Hospital | Brattleboro | E220 Health Care | $116.6M | 12 |
| WORLD LEARNING INC | Brattleboro | Q230 International, Foreign Affairs & National Security | $110.9M | 9 |
| NORTH COUNTRY HOSPITAL & HEALTH CENTER INC | Newport | E220 Health Care | $109.1M | 11 |
| Copley Hospital Inc | Morrisville | E22 Health Care | $107.6M | 12 |
| VERMONT ELECTRIC COOPERATIVE INC | Johnson | — | $103.9M | 20 |
| SAINT MICHAEL'S COLLEGE | Colchester | B430 Education | $98.4M | 10 |
| Brattleboro Retreat | Brattleboro | F31 Mental Health & Crisis Intervention | $95.5M | 10 |
| Aspire Living & Learning Inc | Montpelier | P700 Human Services | $93.7M | 10 |
| BENNINGTON COLLEGE CORPORATION | Bennington | B420 Education | $86.8M | 9 |
| Windsor Hospital Corporation | Windsor | E220 Health Care | $76.5M | 17 |
| Gifford Medical Center Inc | Randolph | E20 Health Care | $75.3M | 10 |
| WASHINGTON COUNTY MENTAL HEALTH SERVICES INC | Montpelier | — | $70.7M | 8 |
| HEALTH CARE & REHABILITATION SERVICES OF SOUTHEASTERN VT INC | Springfield | E32Z Health Care | $66.1M | 11 |
| Springfield Hospital Inc | Springfield | E220 Health Care | $64.2M | 9 |
| UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE FOUNDATION INC | Burlington | B114 Education | $62.4M | 12 |
| COMMUNITY HEALTH CENTERS OF THE RUTLAND REGION | Rutland | E30 Health Care | $60.7M | 8 |
| NORTHEAST KINGDOM HUMAN SERVICES INC | Newport | — | $58.6M | 8 |
| NORTHWESTERN COUNSELING & SUPPORT SERVICES | St Albans | F320 Mental Health & Crisis Intervention | $55.6M | 7 |
| ONE TREE PLANTED INC | Shelburne | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $54.8M | 6 |
| THE VERMONT COMMUNITY FOUNDATION | Middlebury | T310 Philanthropy, Voluntarism & Grantmaking Foundations | $54M | 12 |
| VERMONT HOUSING FINANCE AGENCY | Burlington | L122 Housing & Shelter | $46.6M | 5 |
| LANDMARK COLLEGE INC | Putney | — | $45.5M | 7 |
| COMMUNITY HEALTH CENTERS OF BURLINGTON INC | Burlington | E32Z Health Care | $42.4M | 8 |
| Vermont Law School | South Royalton | B53Z Education | $41.7M | 8 |
| THE UNIVERSITY OF VERMONT HEALTH NETWORK | Burlington | F19 Mental Health & Crisis Intervention | $40.5M | 25 |
| CHAMPLAIN HOUSING TRUST | Burlington | L200 Housing & Shelter | $40.5M | 8 |
| CHAMPLAIN VALLEY OFFICE OF ECONOMIC OPPORTUNITY INC | Burlington | S200 Community Improvement & Capacity Building | $40.3M | 4 |
| St Johnsbury Academy | St Johnsbury | B250 Education | $38.4M | 7 |
| WAKE ROBIN CORPORATION | Shelburne | P750 Human Services | $38.3M | 7 |
| Carlos G Otis Health Care Center | Townshend | E22 Health Care | $38.2M | 8 |
| UPPER VALLEY SERVICES INC | White River Junction | P820 Human Services | $37.6M | 6 |
| RUTLAND MENTAL HEALTH SERVICES INC | Rutland | F80Z Mental Health & Crisis Intervention | $36.3M | 5 |
| COLLEGE INSURANCE COMPANY | Colchester | Y200 Mutual & Membership Benefit | $36.3M | 5 |
| Northern Counties Health Care Inc | St Johnsbury | E39Z Health Care | $35.6M | 8 |
| HIMALAYAN CATARACT PROJECT INC | Norwich | Q300 International, Foreign Affairs & National Security | $32.2M | 12 |
| VERMONT FOODBANK | Barre | K31I Food, Agriculture & Nutrition | $31.3M | 9 |
