| ROCKEFELLER FAMILY FUND INC | New York | T900 Philanthropy, Voluntarism & Grantmaking Foundations | $60.4M | 7 |
| GRAHAM WINDHAM | Brooklyn | P200 Human Services | $60.3M | 10 |
| GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT INC | New York | H80 Medical Research | $60.2M | 12 |
| WELFARE FUND OF LOCAL NO ONE IATSE | New York | — | $60.2M | 3 |
| TEAMSTERS LOCAL 210 AFFILIATED HEALTH & INSURANCE FUND | Staten Island | Y44 Mutual & Membership Benefit | $60.1M | 0 |
| Little Falls Hospital | Little Falls | E220 Health Care | $60.1M | 13 |
| FAMILY SERVICE LEAGUE INC | Huntington | P400 Human Services | $59.9M | 16 |
| PARSONS CHILD AND FAMILY CENTER | Albany | P300 Human Services | $59.9M | 7 |
| EGER HEALTH CARE AND REHABILITATION CENTER | Staten Island | E91 Health Care | $59.8M | 9 |
| HENRY STREET SETTLEMENT | New York | P280 Human Services | $59.7M | 7 |
| KIPP NEW YORK INC | New York | B12 Education | $59.7M | 16 |
| BRONX CHARTER SCHOOL FOR EXCELLENCE | Bronx | B29 Education | $59.7M | 10 |
| VOLUNTARY HOSPITALS HOUSE STAFF BENEFITS PLAN | Long Island City | Y43 Mutual & Membership Benefit | $59.4M | 0 |
| MS FOUNDATION FOR WOMEN INC | Brooklyn | R240 Civil Rights, Social Action & Advocacy | $59.4M | 9 |
| NEIGHBORHOOD HEALTH CENTER OF WNY INC | Buffalo | — | $59.1M | 7 |
| JOINT INDUSTRY BOARD OF THE ELECTRICAL INDUSTRY | Flushing | — | $59M | 9 |
| BROOKVILLE CENTER FOR CHILDRENS SERVICES INC | Brookville | P20 Human Services | $58.9M | 6 |
| FJC | New York | I990 Crime & Legal-Related | $58.9M | 6 |
| CENTER FOR ALTERNATIVE SENTENCING AND EMPLOYMENT SERVICES INC | Brooklyn | — | $58.9M | 13 |
| CDS MONARCH INC | Webster | P73Z Human Services | $58.8M | 9 |
| THE EDUCATIONAL ALLIANCE INC | New York | — | $58.8M | 8 |
| The Pierpont Morgan Library | New York | B700 Education | $58.7M | 8 |
| RETHINK FOOD NYC INC | New York | K30 Food, Agriculture & Nutrition | $58.7M | 11 |
| COBBLE HILL HEALTH CENTER INC | Brooklyn | E91Z Health Care | $58.6M | 8 |
| LAMBDA LEGAL DEFENSE & EDUCATION FUND INC | New York | R20Z Civil Rights, Social Action & Advocacy | $58.5M | 14 |
| INTERNATIONAL COUNCIL OF SHOPPING CENTERS INC | New York | — | $58.4M | 8 |
| SENIOR CARE CONNECTION INC | Schenectady | — | $58.2M | 14 |
| ICNA RELIEF USA PROGRAMS INC | New Hyde Park | M20 Public Safety, Disaster Preparedness & Relief | $58M | 2 |
| CROUSE MEDICAL PRACTICE PLLC | Syracuse | E30 Health Care | $58M | 8 |
| WILLIAM J BRENNAN CENTER FOR JUSTICE INC | New York | B40Z Education | $57.9M | 12 |
| NYSARC INC - WESTCHESTER COUNTY CHAPTER | Hawthorne | P700 Human Services | $57.9M | 7 |
| GRACE CHURCH SCHOOL | New York | B24 Education | $57.7M | 9 |
| HOMES FOR THE HOMELESS INC | New York | P850 Human Services | $57.5M | 9 |
| SCHUYLER HOSPITAL INC | Montour Falls | E22Z Health Care | $57.5M | 10 |
| ROYAL CHARTER PROPERTIES INC | New York | — | $57.4M | 14 |
| TEAMSTERS LOCAL 237 ADMINISTRATIVE FUND | New York | J40 Employment | $57.3M | 0 |
| ACCESSCNY INC | Syracuse | G23Z Diseases, Disorders & Medical Disciplines | $57.2M | 8 |
| ASTOR SERVICES FOR CHILDREN & FAMILIES | Rhinebeck | P300 Human Services | $57.1M | 9 |
| RISEWELL COMMUNITY SERVICES INC FKA FEDERATION OF ORGANIZATIONS FOR THE NEW | West Babylon | — | $57.1M | 13 |
| CUBRC INC | Buffalo | U32Z Science & Technology | $57M | 18 |
| SURDNA FOUNDATION INC ATT MARC DE VENOGE | New York | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $57M | 5 |
| VISITING NURSE SERVICE OF NEW YORK | New York | E92 Health Care | $56.9M | 7 |
| KEUKA COLLEGE | Keuka Park | B420 Education | $56.9M | 13 |
| LOCAL 580 - INSURANCE FUND | New York | — | $56.9M | 4 |
| THE GRADUATE CENTER FOUNDATION INC | New York | — | $56.7M | 5 |
| STANLEY FAMILY FOUNDATION | Briarcliff Manor | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $56.6M | 0 |
| GOODWILL OF THE FINGER LAKES INC | Rochester | P11 Human Services | $56.6M | 7 |
| UNITED CEREBRAL PALSY ASSOCIATION OF GREATER SUFFOLK INC | Hauppauge | G200 Diseases, Disorders & Medical Disciplines | $56.5M | 7 |
| UNIVERSITY SETTLEMENT SOCIETY OF NEW YORK | New York | — | $56.4M | 7 |
| MERCYFIRST | Syosset | P320 Human Services | $56.3M | 9 |
