| PLANNED PARENTHOODORANGE AND SAN BERNARDINO COUNTIES INC | Anaheim | E420 Health Care | $111.1M | 9 |
| MERIWEST CREDIT UNION | San Jose | W610 Public & Societal Benefit | $110.4M | 17 |
| SUTTER COAST HOSPITAL | Sacramento | E220 Health Care | $110.4M | 8 |
| Jacobs & Cushman San Diego Food Bank | San Diego | K31 Food, Agriculture & Nutrition | $110.3M | 7 |
| BAY AREA COMMUNITY RESOURCES INC | El Cerrito | F220 Mental Health & Crisis Intervention | $109.2M | 11 |
| Adventist Health Delano | Delano | E220 Health Care | $109.1M | 22 |
| KQED INC | San Francisco | A300 Arts, Culture & Humanities | $108.9M | 19 |
| CALIFORNIA ASSOCIATION OF FOOD BANKS | Oakland | K31 Food, Agriculture & Nutrition | $108.9M | 10 |
| SEMI | Milpitas | — | $108.9M | 12 |
| VISTA COMMUNITY CLINIC | Vista | E320 Health Care | $108.8M | 8 |
| LIFEMOVES | Santa Clara | — | $108.6M | 16 |
| Pitzer College | Claremont | B420 Education | $108.5M | 17 |
| CHILDREN'S INSTITUTE INC | Los Angeles | P400 Human Services | $108.5M | 9 |
| SIERRA CLUB FOUNDATION | Oakland | C300 Environment | $108.2M | 7 |
| CARPENTERS VACATION HOLIDAY AND SICK LEAVE TRUST FUND FOR NORTHERN CALIFORNIA | Oakland | — | $107.8M | 4 |
| BAY AREA COMMUNITY HEALTH | Fremont | — | $107.7M | 7 |
| COMMUNITY RESEARCH FOUNDATION INC | San Diego | Z99Z Unknown | $107.5M | 14 |
| NATIONAL ACADEMY OF RECORDING ARTS & SCIENCES INC | Santa Monica | — | $107.1M | 10 |
| CALIFORNIA COLLEGE OF THE ARTS | San Francisco | B420 Education | $107.1M | 12 |
| HIGH TECH HIGH | San Diego | B25 Education | $105.9M | 13 |
| ADVOCACY ACTION FUND INC | Menlo Park | T01 Philanthropy, Voluntarism & Grantmaking Foundations | $105.7M | 5 |
| Apla Health & Wellness | Los Angeles | E99 Health Care | $105.7M | 12 |
| SOUTHERN CALIFORNIA DRUG BENEFIT FUND | Los Angeles | — | $105.1M | 2 |
| SEIU LOCAL 2015 | Los Angeles | — | $104.8M | 144 |
| VISIONS IN EDUCATION | Carmichael | B29 Education | $104.7M | 17 |
| VENICE FAMILY CLINIC | Venice | E320 Health Care | $104.4M | 12 |
| SAMUELI FOUNDATION | Corona Del Mar | T22Z Philanthropy, Voluntarism & Grantmaking Foundations | $104.3M | 1 |
| CALIFORNIA STATE UNIVERSITY FRESNO FOUNDATION | Fresno | B110 Education | $104.2M | 8 |
| CALIFORNIA FIELD IRON WORKER VACATION PERSONAL TIME OFF (PTO) PLAN | Pasadena | — | $104.1M | 0 |
| SAN FRANCISCO OPERA ASSOCIATION | San Francisco | A6A0 Arts, Culture & Humanities | $103.9M | 14 |
| ROESSLER-CHADWICK FOUNDATION | Palos Verdes Peninsula | B200 Education | $103.8M | 15 |
| CHILDREN'S HOSPITAL AT MISSION | Orange | E24Z Health Care | $103.8M | 11 |
| THE SCHMIDT FAMILY FOUNDATION | Palo Alto | B82 Education | $103.7M | 1 |
| WELLNESS WORX INC | Oxnard | E19 Health Care | $103.7M | 0 |
| GRANADA HILLS CHARTER | Granada Hills | B29 Education | $103.2M | 27 |
| ASIAN HEALTH SERVICES | Oakland | E30Z Health Care | $102.8M | 8 |
| MENTAL HEALTH SYSTEMS INC | San Diego | F300 Mental Health & Crisis Intervention | $102.2M | 8 |
| THE PEOPLE CONCERN | Los Angeles | P850 Human Services | $102.2M | 8 |
| COMMON COUNSEL FOUNDATION | Oakland | S50 Community Improvement & Capacity Building | $102.1M | 13 |
| WEINGART CENTER ASSOCIATION | Los Angeles | L410 Housing & Shelter | $101.9M | 5 |
| ENLIGHT FOUNDATION | Palo Alto | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $101.7M | 1 |
| Sheet Metal Workers' Health Plan of Southern California Arizona and Nevada | Manhattan Beach | — | $101.5M | 0 |
| EL PROYECTO DEL BARRIO INC | Arleta | P280 Human Services | $101M | 12 |
| Child Development Resources of Ventura County Inc | Oxnard | B22Z Education | $100.9M | 9 |
| LA MAESTRA FAMILY CLINIC INC | San Diego | E320 Health Care | $100.5M | 16 |
| Goodwill Industries Sacramento Valley & Northern Nevada Inc | Sacramento | J32Z Employment | $100.4M | 13 |
| FIRST ENTERTAINMENT CREDIT UNION FKA CREDIT UNIONS IN THE STATE OF CA | Hollywood | — | $100.3M | 13 |
| KAISER PERMANENTE BERNARD J TYSON SCHOOL OF MEDICINE INC | Oakland | B50 Education | $100.3M | 26 |
| AMALGAMATED TRANSIT UNION-DIV 1277 SCRTD HEALTH & WELFARE FUND | Los Angeles | — | $99.8M | 0 |
| CHAN ZUCKERBERG BIOHUB INC | San Francisco | H99 Medical Research | $99.6M | 11 |
