| Sacramento Region Community Foundation | Sacramento | T310 Philanthropy, Voluntarism & Grantmaking Foundations | $65.8M | 5 |
| MOJAVE RIVER ACADEMY SCHOOLS | Oro Grande | B29 Education | $65.7M | 17 |
| PACIFIC COAST ACADEMY | Poway | B29 Education | $65.5M | 13 |
| UC SANTA BARBARA FOUNDATION | Santa Barbara | B114 Education | $65.3M | 6 |
| CALIFORNIA RURAL INDIAN HEALTH BOARD INC | Roseville | E39Z Health Care | $65.3M | 11 |
| BIOINDUSTRIAL MANUFACTURING AND DESIGN | Emeryville | S40 Community Improvement & Capacity Building | $65.1M | 9 |
| RESNICK FOUNDATION | Los Angeles | T20Z Philanthropy, Voluntarism & Grantmaking Foundations | $64.7M | 0 |
| MOZILLA FOUNDATION | San Francisco | U40 Science & Technology | $64.7M | 16 |
| XQ INSTITUTE | Oakland | B90 Education | $64.7M | 2 |
| MARIN COMMUNITY CLINIC | Novato | E70Z Health Care | $64.6M | 10 |
| MISSION VISTA ACADEMY | Beaumont | B29 Education | $64.6M | 8 |
| G4S SECURE SOLUTIONS (USA) GRP INSURANCE | Irvine | — | $64.4M | 0 |
| CALIFORNIA LIFE & HEALTH INSURANCE GUARANTEE ASSOCIATION | Roseville | — | $64.3M | 1 |
| MOMENTUM FOR HEALTH | San Jose | F300 Mental Health & Crisis Intervention | $64M | 12 |
| Operating Engineers Local 501 Security | West Covina | — | $63.7M | 0 |
| PEDIATRIC AND FAMILY MEDICAL CENTER | Los Angeles | E220 Health Care | $63.7M | 12 |
| CENTURY HOUSING CORPORATION | Culver City | L200 Housing & Shelter | $63.7M | 19 |
| RADY CHILDREN'S HEALTH SERVICES | San Diego | — | $63.4M | 14 |
| GRID ALTERNATIVES | Oakland | C35 Environment | $63.3M | 8 |
| PACIFIC SERVICE CREDIT UNION | Concord | W61 Public & Societal Benefit | $63.2M | 15 |
| PLEDGELING FOUNDATION | San Francisco | T12 Philanthropy, Voluntarism & Grantmaking Foundations | $63.2M | 3 |
| CALFOODS LOGISTICS | Pleasant Hill | K31 Food, Agriculture & Nutrition | $63M | 5 |
| MENLO COLLEGE | Atherton | — | $62.6M | 6 |
| REDWOOD EMPIRE FOOD BANK | Santa Rosa | K31Z Food, Agriculture & Nutrition | $62.6M | 10 |
| HATHAWAY-SYCAMORES CHILD AND FAMILY | Los Angeles | P30 Human Services | $62.5M | 11 |
| NORTHERN CALIFORNIA CARPENTERS REGIONAL | Oakland | — | $62.4M | 19 |
| BLUPEAK CREDIT UNION | San Diego | — | $62.4M | 12 |
| CATHOLIC CHARITIES CYO OF THE | San Francisco | P20Z Human Services | $62.3M | 9 |
| CLAREMONT INVESTMENT FUND | Claremont | B19 Education | $62.1M | 5 |
| SOCIAL GOOD FUND INC | Richmond | B99 Education | $62M | 9 |
| THE EAMES INSTITUTE | Petaluma | A54 Arts, Culture & Humanities | $61.9M | 6 |
| EL CAMINO REAL ALLIANCE | Woodland Hills | — | $61.8M | 14 |
| WESTERN ALLIANCE TRUST FUND | Pasadena | — | $61.8M | 0 |
| VIEWPOINT EDUCATIONAL FOUNDATION | Calabasas | — | $61.7M | 10 |
| EPISCOPAL COMMUNITY SERVICES OF SAN | San Francisco | P85Z Human Services | $61.6M | 8 |
| UNITED TEACHERS LOS ANGELES | Los Angeles | — | $61.5M | 14 |
| THE CAMPANILE FOUNDATION | San Diego | B110 Education | $61.5M | 5 |
| Felton Institute | Alameda | — | $61.5M | 9 |
| SEIU LOCAL 1021 | Oakland | — | $61.4M | 49 |
| COMMUNITY HEALTH SYSTEMS INC | Riverside | — | $61.4M | 12 |
| SKID ROW HOUSING TRUST | Los Angeles | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $61.2M | 3 |
| SAN FRANCISCO MUSEUM OF MODERN ART | San Francisco | A510 Arts, Culture & Humanities | $61.2M | 9 |
| THE EXPLORATORIUM | San Francisco | A500 Arts, Culture & Humanities | $61M | 11 |
| CYPRESS LAWN CEMETERY ASSOCIATION | Colma | — | $61M | 17 |
| GIA HOLDINGS INC | Carlsbad | B19 Education | $60.7M | 4 |
| LifeStream Blood Bank | San Bernardino | E61 Health Care | $60.7M | 7 |
| KAISER HEALTH PLAN ASSET MANAGEMENT INC | Oakland | E110 Health Care | $60.7M | 10 |
| THE INTERNATIONAL SCHOOL OF | San Francisco | B26Z Education | $60.6M | 8 |
| OLE HEALTH | Napa | E32Z Health Care | $60.6M | 14 |
| 1ST UNITED CREDIT UNION | Pleasanton | — | $60.5M | 25 |
