| FEBRES FSC FOUNDATION | Burr Ridge | — | $66.8M | 0 |
| Kenneth C Griffin Museum of Science and | Chicago | A570 Arts, Culture & Humanities | $66.4M | 11 |
| RAVINIA FESTIVAL ASSOCIATION | Highland Park | A600 Arts, Culture & Humanities | $66.2M | 7 |
| MONMOUTH COLLEGE | Monmouth | B420 Education | $66.2M | 10 |
| ILLINOIS WESLEYAN UNIVERSITY | Bloomington | B420 Education | $66.1M | 13 |
| Jo-Carroll Energy Inc (NFP) | Elizabeth | — | $66.1M | 20 |
| Envision Unlimited | Chicago | P82Z Human Services | $66M | 9 |
| ADVENTIST GLENOAKS HOSPITAL | Glendale Heights | — | $65.4M | 0 |
| True Sojourners | Wheaton | Q30 International, Foreign Affairs & National Security | $65.4M | 7 |
| Radiological Society of North America Inc | Oak Brook | G030 Diseases, Disorders & Medical Disciplines | $64.7M | 21 |
| Mendota Community Hospital | Peoria | E220 Health Care | $64.6M | 47 |
| RICHLAND MEMORIAL HOSPITAL | Urbana | E22Z Health Care | $64M | 16 |
| The Joyce Foundation | Chicago | T21 Philanthropy, Voluntarism & Grantmaking Foundations | $63.8M | 18 |
| St Francis Hospital Sisters of the Third Order of St Francis | Litchfield | — | $63.6M | 11 |
| MCKENDREE UNIVERSITY | Lebanon | B420 Education | $63.6M | 7 |
| CROWN FAMILY FOUNDATION | Chicago | T700 Philanthropy, Voluntarism & Grantmaking Foundations | $63.4M | 3 |
| Ann & Robert H Lurie Children's Hospital of Chicago Foundation | Chicago | E110 Health Care | $63.2M | 8 |
| Stanley Manne Childrens Research Institute | Chicago | H110 Medical Research | $63.1M | 5 |
| VERSITI ILLINOIS INC | Aurora | E61Z Health Care | $63M | 17 |
| ALL CHICAGO MAKING HOMELESSNESS HISTORY | Chicago | L80 Housing & Shelter | $62.9M | 7 |
| ILLINOIS EDUCATION ASSOCIATION | Springfield | — | $62.9M | 21 |
| Joint Commission Resources Inc | Oakbrook Terrace | E00B Health Care | $62.9M | 13 |
| ESPERANZA HEALTH CENTERS | Chicago | E21 Health Care | $62.8M | 9 |
| Illinois Agricultural Association | Bloomington | — | $62.7M | 41 |
| Carle West Physician Group Inc | Urbana | E20 Health Care | $62.1M | 18 |
| Tyndale House Ministries | Carol Stream | X83 Religion-Related | $62M | 19 |
| SOCIETY OF ACTUARIES | Chicago | S41 Community Improvement & Capacity Building | $61.9M | 14 |
| Rush University Medical Center's Self-Insurance Trust(see attachment 1) | Chicago | — | $61.7M | 1 |
| INDIVIDUAL ADVOCACY GROUP INC | Romeoville | R99 Civil Rights, Social Action & Advocacy | $61.6M | 7 |
| ELKS NATIONAL FOUNDATION INC | Chicago | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $61.6M | 2 |
| Naperville Psychiatric Ventures | Naperville | E99 Health Care | $61.5M | 20 |
| WESTMINSTER PLACE | Skokie | P750 Human Services | $61.3M | 11 |
| ALPHA KAPPA ALPHA SORORITY INC | Chicago | — | $60.9M | 5 |
| POLISH ROMAN CATHOLIC UNION OF AMERICA | Chicago | — | $60.5M | 18 |
| LUTHERAN HOME FOR THE AGED INC | Arlington Heights | P750 Human Services | $60.4M | 9 |
| Clayton Brown Family Foundation | Wheaton | — | $60.3M | 0 |
| NORTHERN ILLINOIS UNIVERSITY FOUNDATION | DeKalb | B110 Education | $60.3M | 14 |
| UNITED CEREBRAL PALSY SEGUIN OF GREATER | Cicero | P820 Human Services | $59.9M | 8 |
| CHICAGO PAINTERS AND | Darien | — | $59.9M | 4 |
| Lyric Opera of Chicago | Chicago | A6A0 Arts, Culture & Humanities | $59.7M | 13 |
| ASSYRIAN UNIVERSAL ALLIANCE FOUNDATION | Lincolnwood | Q112 International, Foreign Affairs & National Security | $59.5M | 4 |
| MUSCULAR DYSTROPHY ASSOCIATION | Chicago | G50 Diseases, Disorders & Medical Disciplines | $59.4M | 8 |
| SHEET METAL WORKERS LOCAL 73 | Hillside | — | $59.4M | 6 |
| Deaconess Illinois Crossroads Inc | Mount Vernon | E22 Health Care | $59.4M | 5 |
| ADA S MCKINLEY COMMUNITY SERVICES INC | Chicago | P200 Human Services | $59.2M | 10 |
| CRUSADERS CENTRAL CLINIC ASSOCIATION | Rockford | E30Z Health Care | $59.1M | 15 |
| ILLINOIS COLLEGE | Jacksonville | B420 Education | $59.1M | 9 |
| National Merit Scholarship Corporation | Evanston | B820 Education | $59.1M | 8 |
| VNA HEALTH CARE | Aurora | — | $58.8M | 7 |
| AMERICAN SOCIETY OF ANESTHESIOLOGISTS | Schaumburg | — | $58.5M | 77 |
