| Emanate Health Medical Care Foundation | Covina | E30 Health Care | $42.2M | 2 |
| RETIREMENT HOUSING FOUNDATION | Long Beach | P75 Human Services | $42.1M | 17 |
| THE VINTAGE CLUB | Indian Wells | — | $42.1M | 6 |
| VISTA CHARTER PUBLIC SCHOOLS INC | Los Angeles | B29 Education | $42M | 4 |
| ST PAUL'S EPISCOPAL HOME INC | San Diego | P750 Human Services | $42M | 7 |
| Vista Real Public Charter Inc | Oxnard | B29 Education | $42M | 13 |
| CHINATOWN SERVICE CENTER | Los Angeles | — | $41.9M | 10 |
| RIVERSIDE PREPARATORY SCHOOL | Oro Grande | B29 Education | $41.9M | 17 |
| NEW SCHOOLS FUND | Oakland | B110 Education | $41.8M | 11 |
| MONTECITO RETIREMENT ASSOCIATION | Montecito | P750 Human Services | $41.8M | 7 |
| SAN MATEO HOTEL EMPLOYEES AND RESTAURANT EMPLOYEES WELFARE FUND | San Jose | — | $41.8M | 1 |
| HELLMAN FOUNDATION | San Francisco | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $41.7M | 0 |
| EPISCOPAL COMMUNITY SERVICES | National City | P200 Human Services | $41.7M | 7 |
| KINGDOM CAUSES INC CITY NET BEDROCK CREEK | Anaheim | X20 Religion-Related | $41.7M | 8 |
| BLUE STAR FAMILIES INC | Encinitas | W30 Public & Societal Benefit | $41.6M | 10 |
| Protect Our Healthcare | San Rafael | W01 Public & Societal Benefit | $41.6M | 0 |
| UNICARE COMMUNITY HEALTH CENTER INC | Ontario | B99 Education | $41.6M | 8 |
| AMETHOD PUBLIC SCHOOLS | Richmond | B20Z Education | $41.5M | 9 |
| ERIK E AND EDITH H BERGSTROM FOUNDATION A CHARITABLE TRUST | Palo Alto | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $41.5M | 7 |
| LIVING DESERT THE | Palm Desert | C340 Environment | $41.5M | 7 |
| CALIFORNIA MONTESSORI PROJECT | Carmichael | B29 Education | $41.5M | 7 |
| THE POLICE CREDIT UNION OF CALIFORNIA | San Bruno | — | $41.5M | 17 |
| IMAGINE WORLDWIDE | Mill Valley | S80 Community Improvement & Capacity Building | $41.5M | 9 |
| JUNIPERO SERRA CATHOLIC HIGH SCHOOL | San Juan Capistrano | A20 Arts, Culture & Humanities | $41.4M | 5 |
| FIRST CITY CREDIT UNION | Altadena | — | $41.4M | 11 |
| LEADERSHIP PUBLIC SCHOOLS | Oakland | B29 Education | $41.3M | 8 |
| TSAO FAMILY FOUNDATION | Corona Del Mar | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $41.3M | 0 |
| PUBLIC LIBRARY OF SCIENCE | Alhambra | U20 Science & Technology | $41.3M | 11 |
| CLAYTON VALLEY CHARTER HIGH SCHOOL | Concord | B29 Education | $41.3M | 19 |
| CEDARS-SINAI HEALTH SYSTEM | Los Angeles | E21 Health Care | $41.3M | 7 |
| EAST BAY COMMUNITY FOUNDATION | Oakland | T310 Philanthropy, Voluntarism & Grantmaking Foundations | $41.2M | 7 |
| NOVA UKRAINE | Palo Alto | Q12 International, Foreign Affairs & National Security | $41.2M | 2 |
| UNION STATION HOMELESS SERVICES | Pasadena | P85Z Human Services | $41.2M | 8 |
| PALO ALTO UNIVERSITY INC | Palo Alto | B500 Education | $41.1M | 9 |
| Inland Empire Community Foundation | Riverside | T310 Philanthropy, Voluntarism & Grantmaking Foundations | $41.1M | 7 |
| Goodwill Industries of Ventura and Santa Barbara Counties Inc | Oxnard | P29Z Human Services | $41M | 1 |
| RSF SOCIAL FINANCE INC | San Francisco | V210 Social Science | $41M | 12 |
| EDEN INVESTMENTS INC | Hayward | L20Z Housing & Shelter | $40.9M | 3 |
| The Tower Foundation of San Jose State University | San Jose | B11 Education | $40.8M | 13 |
| SAN MATEO ELECTRICAL WORKERS HEALTH PLAN | San Jose | — | $40.8M | 0 |
| CEMENT MASONS SOUTHERN CALIFORNIA HEALTH AND WELFARE FUND | Arcadia | — | $40.8M | 0 |
| PACIFIC ASIAN CONSORTIUM IN EMPLOYMENT | Los Angeles | S200 Community Improvement & Capacity Building | $40.8M | 7 |
| CESAR CHAVEZ FOUNDATION | Keene | — | $40.8M | 7 |
| CHILDREN'S HEALTH COUNCIL INC | Palo Alto | E110 Health Care | $40.7M | 10 |
| JVS SOCAL | Los Angeles | J200 Employment | $40.6M | 9 |
| SELF-HELP FOR THE ELDERLY | San Francisco | P810 Human Services | $40.5M | 7 |
| SAINT JOHN'S HEALTH CENTER FOUNDATION | Santa Monica | E12 Health Care | $40.5M | 8 |
| IBEW Western Utilities Health & Welfare Trust Fund | Pleasanton | — | $40.4M | 0 |
| SPANISH SPEAKING UNITY COUNCIL OF ALAMEDA COUNTY INC | Oakland | S200 Community Improvement & Capacity Building | $40.4M | 9 |
| CORE COMMUNITY ORGANIZED RELIEF EFFORT | Los Angeles | M20 Public Safety, Disaster Preparedness & Relief | $40.4M | 8 |
