| Planned Parenthood California Central | Santa Barbara | E420 Health Care | $26.2M | 10 |
| SANTA BARBARA NEIGHBORHOOD CLINICS | Santa Barbara | E30 Health Care | $26.2M | 9 |
| CHRIST-CENTERED MINISTRIES | Inglewood | P20 Human Services | $26.2M | 7 |
| ROBERT F KENNEDY FARM WORKERS | Keene | — | $26.1M | 2 |
| THE WOOD-CLAEYSSENS FOUNDATION | Santa Barbara | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $26.1M | 7 |
| REGIONAL TASK FORCE ON THE HOMELESS | San Diego | P50 Human Services | $26.1M | 5 |
| LIBERTY HILL FOUNDATION | Los Angeles | T310 Philanthropy, Voluntarism & Grantmaking Foundations | $26.1M | 12 |
| THE CENTER FOR EARLY EDUCATION | West Hollywood | B240 Education | $26.1M | 10 |
| SANTA CRUZ COMMUNITY HEALTH CENTERS | Santa Cruz | E40Z Health Care | $26.1M | 13 |
| THE CARITAS CORPORATION | Irvine | L200 Housing & Shelter | $26M | 5 |
| KINGDOM DEVELOPMENT INC | Riverside | L20 Housing & Shelter | $26M | 0 |
| PARKVIEW LEGACY FOUNDATION | Riverside | E21 Health Care | $26M | 1 |
| Tierra del Sol Foundation | Sunland | J300 Employment | $26M | 5 |
| CLINICA MSR OSCAR A ROMERO | Los Angeles | E32Z Health Care | $26M | 10 |
| ARNOLD AND MABEL BECKMAN FOUNDATION | Irvine | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $25.9M | 1 |
| Human-I-T | Bell | — | $25.9M | 11 |
| THE BRANSON SCHOOL | Ross | B25Z Education | $25.9M | 8 |
| LAUNCHPAD DEVELOPMENT COMPANY | San Jose | B192 Education | $25.9M | 1 |
| OPEN DOORS INTERNATIONAL INC | Orange | — | $25.9M | 1 |
| Campus Facilities Improvement | San Francisco | T11 Philanthropy, Voluntarism & Grantmaking Foundations | $25.9M | 0 |
| The Green Foundation | Pasadena | T20Z Philanthropy, Voluntarism & Grantmaking Foundations | $25.9M | 1 |
| THE GROVE FOUNDATION | Los Altos | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $25.9M | 0 |
| PUBLIC COUNSEL | Los Angeles | I80 Crime & Legal-Related | $25.8M | 12 |
| SONOMA LAND TRUST | Santa Rosa | C340 Environment | $25.8M | 7 |
| AAM FOUNDATION | Novato | Q33 International, Foreign Affairs & National Security | $25.8M | 0 |
| IMAGINE WORLDWIDE | Mill Valley | S80 Community Improvement & Capacity Building | $25.7M | 9 |
| SAG-AFTRA & INDUSTRY SOUND RECORDINGS | Valley Village | S41 Community Improvement & Capacity Building | $25.7M | 0 |
| GIRL SCOUTS OF GREATER LOS ANGELES | Inglewood | O42 Youth Development | $25.7M | 8 |
| TRI-STATE COMMUNITY HEALTHCARE CENTER | Glendale | E32 Health Care | $25.7M | 8 |
| WAKELAND HOUSING AND DEVELOPMENT CORP | San Diego | L21 Housing & Shelter | $25.6M | 7 |
| ANAHEIMORANGE COUNTY VISITOR | Anaheim | — | $25.6M | 11 |
| Orange County Rescue Mission Inc | Tustin | L410 Housing & Shelter | $25.6M | 5 |
| SOUTHERN CALIFORNIA HEALTH & | Lynwood | P82 Human Services | $25.6M | 10 |
| THE OAKLAND PUBLIC EDUCATION FUND | Oakland | B99 Education | $25.5M | 7 |
| DOHENY EYE INSTITUTE | Pasadena | — | $25.5M | 6 |
| CLARKSVILLE CHARTER SCHOOL | El Dorado Hills | B20 Education | $25.5M | 9 |
| DOLORES STREET COMMUNITY SERVICES INC | San Francisco | L410 Housing & Shelter | $25.5M | 5 |
| The Adult Skills Center | Van Nuys | — | $25.5M | 7 |
| BRENTWOOD COUNTRY CLUB | Los Angeles | — | $25.4M | 7 |
| The Shanahan Family Charitable | Pasadena | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $25.4M | 1 |
| CATHOLIC CHARITIES OF CALIFORNIA | Sacramento | — | $25.4M | 5 |
| GREAT VALLEY ACADEMY INC | Modesto | B24 Education | $25.4M | 6 |
| IMMIGRANT LEGAL RESOURCE CENTER | San Francisco | P84Z Human Services | $25.3M | 6 |
| SAN JOSE CONSERVATION CORPS | San Jose | — | $25.3M | 7 |
| Sourcewise | Santa Clara | P81Z Human Services | $25.3M | 5 |
| SAN DIEGO RESCUE MISSION INC | San Diego | L410 Housing & Shelter | $25.3M | 3 |
| CALIFORNIA TEACHERS ASSOC EMPLOYEES' | Alameda | — | $25.3M | 0 |
| SOUTHERN CALIFORNIA EDISON CO VEBA TR | Rosemead | — | $25.3M | 1 |
| SANTA CATALINA SCHOOL | Monterey | B200 Education | $25.3M | 11 |
| WINE INSTITUTE | Sacramento | — | $25.2M | 11 |
