| IBEW LOCAL 18 HEALTH AND WELFARE TRUST | Los Angeles | — | $206.3M | 14 |
| SAINT FRANCIS MEMORIAL HOSPITAL | San Francisco | E220 Health Care | $205.6M | 15 |
| COH HOLDCO INC | Duarte | E21 Health Care | $201.7M | 14 |
| THE SAN FRANCISCO FOUNDATION | San Francisco | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $200M | 11 |
| UNIVERSITY OF REDLANDS | Redlands | B430 Education | $199.8M | 18 |
| GERSON BAKAR FOUNDATION | San Francisco | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $198.3M | 0 |
| SAN DIEGO COUNTY CAPITAL ASSET LEASING CORPORATION | San Diego | — | $198.1M | 0 |
| SIERRA HEALTH FOUNDATION CENTER FOR HEALTH PROGRAM MANAGEMENT | Sacramento | E70 Health Care | $197.5M | 2 |
| Daffy Charitable Fund | Los Altos | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $197.2M | 0 |
| VITAMIN ANGEL ALLIANCE INC | Goleta | K40 Food, Agriculture & Nutrition | $197.1M | 8 |
| THE LINUX FOUNDATION | San Francisco | S41 Community Improvement & Capacity Building | $196M | 14 |
| WESTERN GROWERS ASSURANCE TRUST FUND | Irvine | — | $195.7M | 10 |
| KLAMATH RIVER RENEWAL CORPORATION | Berkeley | C32 Environment | $195.5M | 4 |
| GENE HAAS FOUNDATION | Oxnard | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $195.1M | 0 |
| SENECA FAMILY OF AGENCIES | Oakland | — | $193.1M | 8 |
| Adventist Health Clearlake Hospital Inc | Clearlake | E220 Health Care | $191.7M | 22 |
| REDWOOD COAST DEVELOPMENTAL SERVICES CORPORATION | Ukiah | — | $191.4M | 6 |
| Children's Council of San Francisco | San Francisco | P200 Human Services | $191.1M | 7 |
| EASTON SPORTS DEVELOPMENT FOUNDATION II | Van Nuys | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $191.1M | 0 |
| PETCO Animal Supplies Stores Inc Group Benefit Plan And Trust | San Diego | — | $191M | 1 |
| KAISER HOSPITAL ASSET MANAGEMENT INC | Oakland | E110 Health Care | $190.7M | 8 |
| SOUTHERN CALIFORNIA PIPE TRADES HEALTH AND WELFARE FUND | Los Angeles | Y43 Mutual & Membership Benefit | $190.1M | 13 |
| WESTERN STATES REGIONAL COUNCIL OF CARPENTERS | Los Angeles | — | $189.2M | 24 |
| THE RESSLERGERTZ FOUNDATION | Sherman Oaks | B82Z Education | $187.6M | 0 |
| ST JOHN'S COMMUNITY HEALTH | Los Angeles | T99Z Philanthropy, Voluntarism & Grantmaking Foundations | $187.5M | 16 |
| Point Loma Nazarene University | San Diego | B430 Education | $187.3M | 9 |
| ROCKETSHIP EDUCATION | San Jose | B29 Education | $187M | 8 |
| Sharp Coronado Hospital & Healthcare Center | San Diego | — | $186.8M | 16 |
| WIKIMEDIA FOUNDATION INC | San Francisco | B60 Education | $185.4M | 11 |
| CALIFORNIA LUTHERAN UNIVERSITY | Thousand Oaks | B430 Education | $185.1M | 18 |
| Internet Corporation for Assigned Names and Numbers | Los Angeles | U99 Science & Technology | $184.8M | 37 |
| CHILDREN'S HUNGER FUND | Rancho Cascades | Q330 International, Foreign Affairs & National Security | $183.8M | 7 |
| FOUNDATION FOR CALIFORNIA COMMUNITY COLLEGES | Sacramento | B19 Education | $181.8M | 10 |
| SAN FRANCISCO FOOD BANK | San Francisco | — | $181.6M | 12 |
| TARZANA TREATMENT CENTERS INC | Tarzana | F34Z Mental Health & Crisis Intervention | $181.5M | 7 |
| PATH | Los Angeles | P850 Human Services | $181.1M | 7 |
| HENRY E HUNTINGTON LIBRARY AND ART GALLERY | San Marino | A540 Arts, Culture & Humanities | $180.7M | 10 |
| COMMUNITY PARTNERS | Los Angeles | S20 Community Improvement & Capacity Building | $180.3M | 7 |
| CREDIT UNION OF SOUTHERN CALIFORNIA | Anaheim | — | $179.5M | 30 |
| Mexican American Opportunity Foundation | Montebello | J220 Employment | $179M | 10 |
| Community Health Centers of the Central Coast Inc | Santa Maria | E320 Health Care | $177.1M | 11 |
| SAN FRANCISCO CULINARY BARTENDERS & SERVICE EMPLOYEES WELFARE FUND | Pleasanton | — | $176.9M | 1 |
| FOOD FORWARD INC | North Hollywood | K30 Food, Agriculture & Nutrition | $175.2M | 7 |
| OPERATING ENGINEERS LOCAL UNION NO 3 VACATION HOLIDAY AND SICK PAY TRUST FUND | Alameda | Y35 Mutual & Membership Benefit | $174.6M | 0 |
| California Nurses Association | Oakland | — | $173.9M | 33 |
| PREMIER AMERICA CREDIT UNION | Chatsworth | — | $172.5M | 22 |
| HEALTHRIGHT 360 | San Francisco | — | $172.3M | 10 |
| SAINT MARY'S COLLEGE OF CALIFORNIA | Moraga | B430 Education | $172.1M | 7 |
| PACIFIC CENTRAL COAST HEALTH CENTERS | San Francisco | E21 Health Care | $171.8M | 15 |
| CEDARS-SINAI MARINA HOSPITAL (FKA CFHS HOLDINGS INC) | Marina Del Rey | E20 Health Care | $171.5M | 13 |
