| NORTHEAST VALLEY HEALTH CORPORATION | San Fernando | E320 Health Care | $170.1M | 16 |
| ACADEMY OF MOTION PICTURE ARTS AND SCIENCES | Beverly Hills | — | $170.1M | 16 |
| HIGHLANDS COMMUNITY CHARTER SCHOOL AND TECHNICAL SCHOOLS | Sacramento | B29 Education | $169.5M | 7 |
| COMMUNITY ACTION PARTNERSHIP OF KERN | Bakersfield | P200 Human Services | $169.2M | 12 |
| SIERRA CLUB | Oakland | — | $169M | 29 |
| CHILDREN'S HOME SOCIETY OF CALIFORNIA | Los Angeles | P300 Human Services | $168.1M | 7 |
| ORANGE COUNTY COMMUNITY FOUNDATION | Irvine | T310 Philanthropy, Voluntarism & Grantmaking Foundations | $167.9M | 9 |
| CALIFORNIA COAST CREDIT UNION | San Diego | — | $167.6M | 18 |
| SANTA MONICA UNITE HERE HEALTH BENEFIT PLAN | Los Angeles | — | $166.9M | 0 |
| USC VERDUGO HILLS HOSPITAL | Glendale | E20 Health Care | $165.9M | 19 |
| VALLEY CHILDREN'S MEDICAL GROUP | Madera | G98 Diseases, Disorders & Medical Disciplines | $162.2M | 9 |
| OPTIONS FOR LEARNING | West Covina | — | $161.8M | 10 |
| COMMUNITY HEALTH GROUP | Chula Vista | E80 Health Care | $161.5M | 20 |
| The Salk Institute for Biological Studies | La Jolla | U500 Science & Technology | $161.2M | 12 |
| DONOR NETWORK WEST | San Ramon | — | $160.6M | 16 |
| CALIFORNIA TRAVEL AND TOURISM COMMISSION | Sacramento | S41 Community Improvement & Capacity Building | $159.7M | 9 |
| WESTERN REGIONAL MEDICAL CENTER INC | Duarte | E24 Health Care | $159.3M | 18 |
| MOUNT SAINT MARY'S UNIVERSITY | Los Angeles | B430 Education | $158.2M | 15 |
| DIRECTORS GUILD OF AMERICA - PRODUCER HEALTH PLAN | Los Angeles | — | $158M | 9 |
| HOAG HOSPITAL FOUNDATION | Newport Beach | E112 Health Care | $157.9M | 8 |
| FOOD BANK OF CONTRA COSTA AND SOLANO | Concord | K310 Food, Agriculture & Nutrition | $156.9M | 9 |
| KIPP BAY AREA SCHOOLS | Oakland | B25 Education | $156.9M | 12 |
| The Roberts Foundation | San Mateo | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $156.2M | 0 |
| MUSEUM ASSOCIATES | Los Angeles | A51 Arts, Culture & Humanities | $156.1M | 14 |
| Monterey Bay Aquarium Foundation | Monterey | D110 Animal-Related | $155.9M | 18 |
| Fresno County Economic Opportunities Commission | Fresno | P200 Human Services | $155.6M | 8 |
| LUCAS MUSEUM OF NARRATIVE ART | Los Angeles | A50 Arts, Culture & Humanities | $154.8M | 1 |
| LA CLINICA DE LA RAZA INC | Oakland | E300 Health Care | $154.4M | 13 |
| MARY E BAZAR-ROBIN FOUNDATION | Woodland Hills | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $154.1M | 1 |
| DAMERON HOSPITAL ASSOCIATION | Stockton | E220 Health Care | $153.9M | 6 |
| Child Action Inc | Rancho Cordova | P30J Human Services | $152.1M | 16 |
| THE HEISING-SIMONS FOUNDATION | Los Altos | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $152.1M | 5 |
| ART CENTER COLLEGE OF DESIGN | Pasadena | B420 Education | $150.1M | 11 |
| PLANNED PARENTHOOD MAR MONTE INC | San Jose | E420 Health Care | $150M | 11 |
| JEWISH COMMUNITY FOUNDATION OF LOS ANGELES | Los Angeles | T70 Philanthropy, Voluntarism & Grantmaking Foundations | $149.8M | 15 |
| PACKARD CHILDREN'S HEALTH ALLIANCE | Palo Alto | E30 Health Care | $149.4M | 18 |
| RIPPLEWORKS INC | Redwood City | Q30 International, Foreign Affairs & National Security | $149.4M | 2 |
| Southern California IBEW-NECA Health Trust Fund | Pasadena | — | $149.2M | 0 |
| CENTER FOR ELDERS' INDEPENDENCE INC | Oakland | P750 Human Services | $148.9M | 10 |
| JEWISH COMMUNITY FEDERATION OF SAN FRANCISCO THE PENINSULA MARIN & SONOMA | San Francisco | T700 Philanthropy, Voluntarism & Grantmaking Foundations | $148.2M | 13 |
| ARROWHEAD CENTRAL CREDIT UNION | Rancho Cucamonga | — | $148.2M | 16 |
| RIDGECREST REGIONAL HOSPITAL | Ridgecrest | E22 Health Care | $147.7M | 8 |
| CHINESE HOSPITAL ASSOCIATION | San Francisco | E220 Health Care | $146.6M | 12 |
| JWCH INSTITUTE INC | Commerce | E70Z Health Care | $146.2M | 19 |
| Film Musicians Secondary Markets Fund | Encino | S41 Community Improvement & Capacity Building | $146.1M | 7 |
| ASPIRE HEALTH PLAN | Monterey | E31 Health Care | $146M | 11 |
| SEIU UNITED HEALTH CARE WORKERS - WEST LOCAL 2005 | Oakland | — | $145.9M | 258 |
| CLINICAS DEL CAMINO REAL INC | Ventura | E300 Health Care | $145.5M | 15 |
| THE CALIFORNIA ENDOWMENT | Los Angeles | T22E Philanthropy, Voluntarism & Grantmaking Foundations | $145.2M | 27 |
| PROVIDENT CREDIT UNION | Redwood City | — | $145.1M | 18 |
