| PROGRESSIVE HOUSING INC | Olympia Fields | P80Z Human Services | $20.9M | 12 |
| Eastern Illinois University Foundation | Charleston | B43I Education | $20.9M | 0 |
| AMERICA FOR BULGARIA FOUNDATION | Homer Glen | Q32 International, Foreign Affairs & National Security | $20.9M | 15 |
| GOODWILL INDUSTRIES OF CENTRAL ILLINOIS | Peoria | J32Z Employment | $20.8M | 2 |
| COVENANT LIVING AT THE HOLMSTAD INC | Batavia | P750 Human Services | $20.8M | 18 |
| National Board of Certification and Recertification for Nurse Anesthetists | Chicago | S41 Community Improvement & Capacity Building | $20.8M | 9 |
| SAL FAMILY AND COMMUNITY SERVICES | Moline | — | $20.7M | 5 |
| CLARA ABBOTT FOUNDATION | Abbott Park | Y20 Mutual & Membership Benefit | $20.7M | 2 |
| PECO ENERGY COMPANY RETIREE MEDICAL TRUST C/O BENEFITS ACCOUNTING | Chicago | — | $20.7M | 1 |
| Aspire of Illinois | Hillside | P82Z Human Services | $20.6M | 6 |
| THE ILLINOIS SAINT ANDREW SOCIETY | North Riverside | P750 Human Services | $20.6M | 7 |
| NORTHWESTERN UNIVERSITY SETTLEMENT ASSOCIATION | Chicago | P200 Human Services | $20.5M | 7 |
| Heartland Alliance International LLC | Chicago | R99 Civil Rights, Social Action & Advocacy | $20.4M | 5 |
| Central Illinois Foodbank Inc | Springfield | K31Z Food, Agriculture & Nutrition | $20.3M | 2 |
| FIRST NORTHERN CREDIT UNION | Chicago | — | $20.2M | 13 |
| Nourishing Hope | Chicago | — | $20.2M | 6 |
| Auditorium Theatre of Roosevelt University Inc | Chicago | A650 Arts, Culture & Humanities | $20.2M | 9 |
| EMBARRAS RIVER BASIN AGENCY INC | Greenup | S200 Community Improvement & Capacity Building | $20.2M | 2 |
| GIVE N KIND | Buffalo Grove | W99 Public & Societal Benefit | $20.2M | 3 |
| Moosehaven Inc | Mooseheart | L220 Housing & Shelter | $20.1M | 7 |
| OEU-965 HEALTH BENEFIT PLAN | Springfield | — | $20.1M | 0 |
| METAMORA COMMUNITY NURSING HOME | Metamora | P750 Human Services | $20.1M | 5 |
| STUDIO MECHANICS LOCAL 476 HEALTH AND WELFARE FUND | Chicago | — | $20.1M | 2 |
| CHRISTOPHER HOUSE | Chicago | P280 Human Services | $20.1M | 7 |
| Timothy Christian Schools | Elmhurst | — | $20M | 7 |
| BOYS AND GIRLS CLUBS OF CHICAGO | Chicago | O230 Youth Development | $20M | 8 |
| SERTOMA CENTRE INC | Alsip | — | $20M | 2 |
| KESHET | Northbrook | — | $20M | 5 |
| ADVOCATE HEALTH CARE NETWORK | Oak Brook | E210 Health Care | $20M | 17 |
| SARAH BUSH LINCOLN HEALTH SYSTEM | Mattoon | E21Z Health Care | $20M | 6 |
| Dr Scholl Foundation | Northbrook | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $20M | 9 |
| ROCK ISLAND ECONOMIC GROWTH CORPORATION | Rock Island | L20 Housing & Shelter | $20M | 5 |
| Mooseheart Child City and School Inc | Mooseheart | — | $19.9M | 6 |
| LAND OF LINCOLN LEGAL AID INC | East St Louis | I80Z Crime & Legal-Related | $19.9M | 8 |
| ABRI CREDIT UNION | Romeoville | — | $19.9M | 7 |
| Foundation of the American College of Healthcare Executives | Chicago | B600 Education | $19.8M | 9 |
| EUROPEAN AMERICAN ASSOCIATION | Chicago | L20Z Housing & Shelter | $19.8M | 2 |
| TRI-COUNTY OPPORTUNITIES COUNCIL | Rock Falls | S200 Community Improvement & Capacity Building | $19.8M | 2 |
| Rural Health Inc | Anna | E39Z Health Care | $19.8M | 7 |
| TAMID HEALTHCARE NFP | Lincolnwood | E80 Health Care | $19.7M | 7 |
| PRITZKER TRAUBERT FOUNDATION | Chicago | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $19.7M | 1 |
| RADIANT LIFE MINISTRIES INC | Marion | A30Z Arts, Culture & Humanities | $19.7M | 5 |
| SOCIETY OF WOMEN ENGINEERS | Chicago | S41Z Community Improvement & Capacity Building | $19.7M | 9 |
| THE CLEVELAND AVENUE FOUNDATION FOR EDUCATION GROUP | Chicago | B82 Education | $19.6M | 4 |
| International Sanitary Supply Association | Rosemont | — | $19.6M | 14 |
| RENEE AND LESTER CROWN CHARITABLE TRUST FOR JEWISH CAUSES | Chicago | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $19.6M | 0 |
| AMERICAN ACADEMY OF SLEEP MEDICINE | Darien | — | $19.6M | 26 |
| MIDWEST OPERATING ENGINEERS CONSTRUCTION INDUSTRY & SERVICE TRUST FUND | Countryside | — | $19.5M | 1 |
| THE ARC OF THE QUAD CITIES AREA | Rock Island | P820 Human Services | $19.5M | 4 |
| A SAFE HAVEN FOUNDATION | Chicago | F22 Mental Health & Crisis Intervention | $19.4M | 4 |
