| COTTONWOOD COMMUNITY ALTERNATIVES | Englewood | P70Z Human Services | $11.1M | 4 |
| EDUCATION COMMISSION OF THE STATES | Northglenn | B00F Education | $11M | 7 |
| St Francis Nursing Center Inc | Colorado Springs | — | $11M | 3 |
| UNION COLONY SCHOOLS | Greeley | B29 Education | $11M | 0 |
| THE GALENA FOUNDATION | Denver | T20J Philanthropy, Voluntarism & Grantmaking Foundations | $10.9M | 0 |
| MOUNT ST VINCENT HOME INC | Denver | — | $10.9M | 8 |
| COMMUNITY FOUNDATION BOULDER COUNTY | Boulder | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $10.9M | 3 |
| ARABIAN HORSE ASSOCIATION | Greenwood Village | — | $10.8M | 4 |
| Western Resource Advocates | Boulder | I83Z Crime & Legal-Related | $10.8M | 10 |
| JOHNNYS AMBASSADORS INC | Castle Rock | F99 Mental Health & Crisis Intervention | $10.8M | 2 |
| CATALYST CAMPUS FOR TECHNOLOGY AND INNOVATION INC | Colorado Springs | Q43 International, Foreign Affairs & National Security | $10.8M | 4 |
| COLORADO CHAUTAUQUA ASSOCIATION | Boulder | Z99Z Unknown | $10.8M | 3 |
| DENVER METRO CHAMBER OF COMMERCE | Denver | — | $10.8M | 9 |
| LINCOLN ACADEMY CHARTER SCHOOL | Arvada | B29 Education | $10.7M | 2 |
| MERCY HOUSING CALWEST | Denver | L20Z Housing & Shelter | $10.7M | 15 |
| SHEILA FORTUNE FOUNDATION INC | Boulder | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $10.7M | 1 |
| COMMUNITY REACH CENTER SYSTEMS INC | Westminster | — | $10.7M | 9 |
| NORTH COLORADO HEALTH ALLIANCE | Evans | E60 Health Care | $10.7M | 1 |
| HIGH PLAINS COMMUNITY HEALTH CENTER | Lamar | E21 Health Care | $10.7M | 5 |
| RAISE THE FUTURE | Denver | P310 Human Services | $10.7M | 7 |
| Villages Ltd | Fort Collins | — | $10.6M | 2 |
| Sabrina Merage Foundation | Englewood | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $10.6M | 0 |
| KIDS CROSSING | Colorado Springs | P320 Human Services | $10.6M | 3 |
| SERVICE EMPLOYEES INTERNATIONAL UNION LOCAL 105 | Denver | — | $10.5M | 32 |
| COLORADO YOUTH CORPS ASSOCIATION | Denver | C12 Environment | $10.5M | 1 |
| ECO-CYCLE INC | Boulder | C270 Environment | $10.5M | 5 |
| COMMUNITY LEADERSHIP ACADEMY INC | Commerce City | B29 Education | $10.4M | 3 |
| ARAPAHOE CREDIT UNION | Littleton | — | $10.3M | 4 |
| PUEBLO SCHOOL FOR ARTS AND SCIENCES | Pueblo | B29 Education | $10.3M | 0 |
| Exceptional Kids Inc | Centennial | E99 Health Care | $10.3M | 1 |
| CENTER FOR IMPROVING VALUE IN HEALTH CARE | Denver | H05 Medical Research | $10.3M | 7 |
| GREELEY INDEPENDENCE STAMPEDE INC | Greeley | — | $10.3M | 1 |
| PUEBLO DIVERSIFIED INDUSTRIES INC | Pueblo | J33Z Employment | $10.3M | 1 |
| INTERNATIONAL BROTHERHOOD OF ELECTRICAL WORKERS LOCAL UNION 111 | Denver | — | $10.3M | 17 |
| Vega Collegiate Academy | Aurora | B29 Education | $10.3M | 1 |
| COMMUNITY RESOURCES AND HOUSING DEVELOPMENT CORPORATION | Westminster | L21Z Housing & Shelter | $10.2M | 2 |
| DENVER METRO ASSOCIATION OF REALTORS FKA DENVER BOARD OF REALTORS INC | Denver | — | $10.2M | 4 |
| EARLY LEARNING VENTURES | Englewood | T23 Philanthropy, Voluntarism & Grantmaking Foundations | $10.2M | 2 |
| PIKES PEAK REAL ESTATE FOUNDATION | Colorado Springs | L12 Housing & Shelter | $10.2M | 3 |
| ROCKY MOUNTAIN BIRD OBSERVATORY | Brighton | D320 Animal-Related | $10.1M | 3 |
| ARCHWAY INVESTMENT CORPORATION INC | Denver | L20 Housing & Shelter | $10.1M | 5 |
| GRIFFITH CENTERS FOR CHILDREN INC | Northglenn | F330 Mental Health & Crisis Intervention | $10.1M | 2 |
| THE FRIENDSHIP BRIDGE | Lakewood | Q99M International, Foreign Affairs & National Security | $10.1M | 3 |
| BELLA NATURAL WOMEN'S CARE | Englewood | — | $10.1M | 9 |
| MORIAH FOUNDATION | Colorado Springs | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $10M | 2 |
| ADVENTURE UNLIMITED | Greenwood Village | N20Z Recreation & Sports | $10M | 3 |
| RIDGEVIEW CLASSICAL SCHOOLS | Fort Collins | B29 Education | $10M | 4 |
| Golden View Classical Academy | Golden | B29 Education | $10M | 2 |
| MERCY HOUSING MOUNTAIN PLAINS | Denver | P40 Human Services | $9.9M | 9 |
| New Summit Academy | Colorado Springs | B29 Education | $9.9M | 1 |
