| Greater Europe Mission | Wheaton | X20Z Religion-Related | $28.1M | 9 |
| Rabia Institute of Medical Sciences | South Barrington | B50 Education | $28.1M | 0 |
| CHADDOCK ATTACHMENT AND TRAUMA SERVICES | Quincy | — | $28M | 2 |
| EARTHMOVER CREDIT UNION | Aurora | — | $28M | 18 |
| GTIA INVESTMENTS NFP INC | Oakbrook Terrace | — | $27.9M | 3 |
| Islamic Food & Nutrition Council of America | Des Plaines | — | $27.9M | 7 |
| CENTRAL LABORERS' WELFARE FUND LABORERS' WELFARE FUND | Jacksonville | — | $27.7M | 0 |
| CUNNINGHAM CHILDRENS HOME OF URBANA IL | Urbana | P200 Human Services | $27.7M | 7 |
| INTERNATIONAL ASSOCIATION OF HEAT & FROST INSULATORS LOCAL 17 WELFARE FUND | Tinley Park | — | $27.7M | 3 |
| AMERICAN FEDERATION OF TEACHERS ILLINOIS STATE FEDERATION | Westmont | — | $27.6M | 60 |
| Search Inc | Chicago | — | $27.6M | 13 |
| CHINESE AMERICAN SERVICE LEAGUE INC | Chicago | S800 Community Improvement & Capacity Building | $27.5M | 7 |
| DESERT HEALTH CARE FACILITIES INC | Galesburg | E92 Health Care | $27.5M | 8 |
| NATIONAL TAIWAN UNIVERSITY ACADEMIC DEVELOPMENT FOUNDATION | Willowbrook | B110 Education | $27.5M | 0 |
| SECURE COMMUNITY NETWORK INC | Chicago | M20 Public Safety, Disaster Preparedness & Relief | $27.4M | 12 |
| INSTITUTE OF FOOD TECHNOLOGISTS | Chicago | — | $27.3M | 8 |
| ASSOCIATION FOR CORPORATE GROWTH | Chicago | — | $27.3M | 17 |
| ARCH IRONWORKERS LOCAL 63 WELFARE FUND | Oak Brook | — | $27.3M | 3 |
| THE JOSSELYN CENTER NFP | Northbrook | F60Z Mental Health & Crisis Intervention | $27.1M | 8 |
| COMMUNITY HOSPITAL OF STAUNTON | Staunton | E22Z Health Care | $27.1M | 9 |
| COVENANT HOME | Northbrook | P750 Human Services | $27.1M | 18 |
| PEPCO HOLDINGS INC VEBA TRUST | Chicago | Y43 Mutual & Membership Benefit | $26.9M | 1 |
| AMERICAN FEDERATION OF STATE COUNTY AND MUNICIPAL EMPLOYEES COUNCIL 31 | Springfield | — | $26.9M | 33 |
| WORD ON FIRE CATHOLIC MINISTRIES | Elk Grove Village | X81 Religion-Related | $26.9M | 8 |
| WILLIAM R KENAN JR CHARITABLE TRUST XXXXX2004 | Chicago | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $26.8M | 3 |
| CHAPIN HALL CENTER FOR CHILDREN | Chicago | P70Z Human Services | $26.7M | 13 |
| FRANCES HOUSE INC | Galesburg | P750 Human Services | $26.7M | 4 |
| Wheaton Academy | West Chicago | B25Z Education | $26.7M | 7 |
| NATIONAL UNIVERSITY OF HEALTH SCIENCES | Lombard | — | $26.7M | 5 |
| WASHINGTON AND JANE SMITH COMMUNITY - BEVERLY | Chicago | P750 Human Services | $26.7M | 5 |
| XILIN ASSOCIATION | Naperville | — | $26.7M | 3 |
| THE LIEGL FAMILY FOUNDATION INC | Wilmette | T90 Philanthropy, Voluntarism & Grantmaking Foundations | $26.6M | 0 |
| RAILROAD MAINTENANCE & INDUSTRIAL HEALTH & WELFARE FUND | Springfield | — | $26.4M | 1 |
| WALTER C DISSEN CHARITABLE TRUST | Lake Forest | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $26.4M | 0 |
| COMMUNITY FOUNDATION FOR THE LAND OF LINCOLN INC | Springfield | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $26.2M | 3 |
| ALIVIO MEDICAL CENTER INC | Chicago | E220 Health Care | $26.1M | 10 |
| Chicago Cred Inc | Chicago | J20 Employment | $26.1M | 0 |
| UI LABS INC | Chicago | B05 Education | $26M | 12 |
| EMPLOYERS & OPERATING ENGINEERS LOCAL 520 HEALTH & WELFARE FUND | Swansea | — | $26M | 1 |
| Healthcare Financial Management Association | Downers Grove | — | $25.9M | 12 |
| ILLINOIS HEALTH AND HOSPITAL ASSOCIATION | Naperville | — | $25.8M | 10 |
| SOUTHWEST ORGANIZING PROJECT | Chicago | S20 Community Improvement & Capacity Building | $25.8M | 5 |
| IAA CREDIT UNION | Bloomington | W61 Public & Societal Benefit | $25.7M | 8 |
| NESS HEALTHCARE NFP | Lincolnwood | L22 Housing & Shelter | $25.7M | 13 |
| EMPOWERING PEOPLE INSPIRING CAPABILITIES INC | Peoria | J30Z Employment | $25.7M | 10 |
| STEPPENWOLF THEATRE COMPANY | Chicago | A650 Arts, Culture & Humanities | $25.6M | 12 |
| CHICAGO LOW INCOME HOUSING TRUST FUND | Chicago | L200 Housing & Shelter | $25.5M | 2 |
| LEADING EDUCATORS INC | Chicago | B90 Education | $25.5M | 10 |
| NECA LOCAL 145 WELFARE FUND | Moline | — | $25.5M | 2 |
| AMERICAN ASSOCIATION OF ORTHOPAEDIC SURGEONS | Rosemont | S41 Community Improvement & Capacity Building | $25.3M | 27 |
