| KYIV SCHOOL OF ECONOMICS | Brooklyn | B40 Education | $52.8M | 6 |
| CARMEL RICHMOND NURSING HOME INC | Staten Island | E910 Health Care | $52.7M | 8 |
| Stony Brook Anaesthesiology University Faculty Practice Corporation | Stony Brook | E20 Health Care | $52.1M | 12 |
| 32BJ NORTH HEALTH FUND | New York | Y43 Mutual & Membership Benefit | $52M | 5 |
| OUR LADY OF CONSOLATION GERIATRIC CARE CENTER | West Islip | E910 Health Care | $52M | 9 |
| IRON WORKERS LOCALS 40 361 & 417 | New York | — | $52M | 1 |
| ZETA CHARTER SCHOOLS - NEW YORK CITY | Bronx | B29 Education | $52M | 7 |
| ROYAL CHARTER PROPERTIES INC | New York | — | $52M | 15 |
| COMMUNITY ACCESS INC | New York | F33Z Mental Health & Crisis Intervention | $51.8M | 8 |
| HOUSING WORKS INC | Brooklyn | S41Z Community Improvement & Capacity Building | $51.8M | 8 |
| UFCW LOCAL 2013 HEALTH AND WELFARE FUND | Brooklyn | Y43 Mutual & Membership Benefit | $51.7M | 0 |
| NETWORK RECOVERY SERVICES INC | New York | — | $51.7M | 15 |
| IBEW LOCAL 25 HEALTH & BENEFIT FUND | Hauppauge | — | $51.7M | 0 |
| UNIVERSITY AT BUFFALO NEUROSURGERY INC | Williamsville | E20 Health Care | $51.7M | 31 |
| JEWISH AGENCY FOR ISRAEL - NORTH | New York | Q70 International, Foreign Affairs & National Security | $51.6M | 5 |
| Shen Yun Performing ArtsInc | Cuddebackville | A60 Arts, Culture & Humanities | $51.5M | 2 |
| UNIVERSITY SETTLEMENT SOCIETY OF NEW | New York | — | $51.4M | 7 |
| UNITED UNIVERSITY PROFESSIONS BENEFIT | Albany | — | $51.4M | 10 |
| SUBURBAN ADULT SERVICES INC | Elma | P82Z Human Services | $51.3M | 9 |
| NYSUT MEMBER BENEFITS CATASTROPHE MAJOR | Latham | E80 Health Care | $51.3M | 7 |
| CABRINI OF WESTCHESTER | Dobbs Ferry | — | $51.2M | 9 |
| PROJECT HOSPITALITY INC | Staten Island | — | $51.1M | 7 |
| ADAPT OF THE HUDSON VALLEY INC | Middletown | P70 Human Services | $51M | 5 |
| RAZOM INC | New York | Q33 International, Foreign Affairs & National Security | $51M | 7 |
| THE BROOKLYN INSTITUTE OF ARTS | Brooklyn | A510 Arts, Culture & Humanities | $50.9M | 14 |
| THE CALHOUN SCHOOL | New York | B24Z Education | $50.9M | 8 |
| UNION COMMUNITY HEALTH CENTER INC | Bronx | F300 Mental Health & Crisis Intervention | $50.8M | 9 |
| FEDERATION OF JEWISH COMMUNITIES OF THE | New York | T31J Philanthropy, Voluntarism & Grantmaking Foundations | $50.8M | 0 |
| Science Academies of New York | Syracuse | — | $50.7M | 5 |
| THE STELLA ORTON HOME CARE AGENCY | Staten Island | P440 Human Services | $50.4M | 3 |
| VITAL PROJECTS FUND INC | New York | — | $50.3M | 3 |
| FACULTY-STUDENT ASSOCIATION OF STATE | Buffalo | B43I Education | $50.1M | 6 |
| NYSARC INC CATTARAUGUS | Olean | — | $50M | 0 |
| IAG Charitable Foundation | Albany | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $50M | 0 |
| LOCAL 812 HEALTH FUND | Great Neck | — | $50M | 5 |
| TIEGERMAN SCHOOL | Glen Cove | — | $50M | 8 |
| BRILLA COLLEGE PREPARATORY | Bronx | — | $49.9M | 5 |
| NOITU INSURANCE TRUST FUND | Jamaica | — | $49.7M | 8 |
| FOOD BANK OF CENTRAL NEW YORK | Syracuse | K31 Food, Agriculture & Nutrition | $49.7M | 2 |
| AMERICAN INSTITUTE OF CHEMICAL ENGINEERS | New York | — | $49.7M | 14 |
| Montefiore Einstein Advanced Care | Tarrytown | E30 Health Care | $49.6M | 9 |
| THE EDUCATIONAL ALLIANCE INC | New York | — | $49.3M | 8 |
| FOUNDATION FOR THE GLOBAL COMPACT | New York | Q42 International, Foreign Affairs & National Security | $49.2M | 7 |
| ATTWOOD WILLIAMS CHARITABLE FOUNDATION | Bedford Hills | T50 Philanthropy, Voluntarism & Grantmaking Foundations | $49M | 0 |
| JULIA DYCKMAN ANDRUS MEMORIAL INC | Yonkers | Z99 Unknown | $49M | 8 |
| EVERCARE CHOICE INC | Newburgh | E60I Health Care | $48.9M | 10 |
| WORKING FAMILIES ORGANIZATION INC | Brooklyn | R40 Civil Rights, Social Action & Advocacy | $48.8M | 0 |
| SCOPE EDUCATION SERVICES | Smithtown | B00A Education | $48.8M | 6 |
| CDS LIFE TRANSITIONS INC | Webster | P11 Human Services | $48.7M | 9 |
| COMMUNITY FOUNDATION FOR GREATER BUFFALO | Buffalo | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $48.7M | 8 |
