| The Summit School Incorporated | Winston Salem | B24Z Education | $18.1M | 4 |
| TRANSYLVANIA VOCATIONAL SERVICES IN | Brevard | B122 Education | $18M | 7 |
| Youth Enrichment Program of Wilson | Wilson | — | $18M | 0 |
| BARIUM SPRINGS HOME FOR CHILDREN | Barium Springs | P73 Human Services | $18M | 8 |
| MOUNTAIN ISLAND CHARTER SCHOOL | Mount Holly | B29 Education | $18M | 1 |
| Lutheran Retirement Center - Wilmington Inc | Salisbury | — | $17.9M | 7 |
| GUILFORD COUNTY PARTNERSHIP FOR CHILDREN INC | Greensboro | B012 Education | $17.9M | 2 |
| Community Affordable Housing Equity Corporation | Raleigh | L99Z Housing & Shelter | $17.8M | 10 |
| NC FARM BUREAU FEDERATION INC | Raleigh | — | $17.7M | 0 |
| CLASSROOM CENTRAL INC | Charlotte | B112 Education | $17.7M | 1 |
| WAYNE ACTION GROUP FOR ECONOMIC SOLVENCY INC | Goldsboro | P20 Human Services | $17.7M | 2 |
| FAMILIES AND COMMUNITIES RISING | Durham | T20Z Philanthropy, Voluntarism & Grantmaking Foundations | $17.6M | 5 |
| TRINITY SCHOOL OF DURHAM & CHAPEL HILL | Durham | B20Z Education | $17.5M | 4 |
| Sullenberger Aviation Museum | Charlotte | A72Z Arts, Culture & Humanities | $17.5M | 1 |
| NATIONAL COUNCIL FOR AIR AND STREAM | Cary | — | $17.5M | 10 |
| CHARLOTTE SYMPHONY ORCHESTRA | Charlotte | A690 Arts, Culture & Humanities | $17.4M | 7 |
| NCHA INC | Raleigh | — | $17.4M | 15 |
| WESTERN PIEDMONT COUNCIL OF GOVERNMENTS | Hickory | W00O Public & Societal Benefit | $17.4M | 4 |
| RESCUE MISSIONS MINISTRIES INC | Durham | — | $17.4M | 1 |
| Alleghany County Memorial Hospital Inc | Sparta | E22 Health Care | $17.4M | 6 |
| LIONS SERVICES INC | Charlotte | S80Z Community Improvement & Capacity Building | $17.4M | 1 |
| LSA Management Inc | Salisbury | — | $17.4M | 9 |
| COVENANT VILLAGE INC | Gastonia | P75Z Human Services | $17.2M | 7 |
| Aston Park Health Care Center Inc | Salisbury | T30Z Philanthropy, Voluntarism & Grantmaking Foundations | $17.1M | 9 |
| STATES NEWSROOM | Chapel Hill | A30 Arts, Culture & Humanities | $17.1M | 6 |
| CHILD CARE RESOURCES INC | Charlotte | — | $17.1M | 2 |
| ST DAVID'S SCHOOL | Raleigh | B250 Education | $17.1M | 4 |
| THE UNIVERSITY OF NORTH CAROLINA | Raleigh | B99 Education | $17.1M | 7 |
| North Carolina Community Health Center Assoc Inc | Raleigh | E21Z Health Care | $17.1M | 0 |
| GHA AUTISM SUPPORTS | Albemarle | G84Z Diseases, Disorders & Medical Disciplines | $17.1M | 6 |
| LAKE PRINCE CENTER | Newton | L22 Housing & Shelter | $17M | 5 |
| BENNETT COLLEGE | Greensboro | B420 Education | $16.8M | 11 |
| SOUTHEASTERN COMMUNITY ACTION | Lumberton | P99 Human Services | $16.8M | 2 |
| THE NORTH CAROLINA AQUARIUM SOCIETY | Raleigh | D115 Animal-Related | $16.8M | 4 |
| Research Triangle Foundation of NC | Research Triangle Park | — | $16.7M | 9 |
| METROPOLITAN COMMUNITY HEALTH | Washington | E20 Health Care | $16.7M | 6 |
| CAROLINA FRIENDS SCHOOL | Durham | — | $16.6M | 2 |
| FOOD BANK OF THE ALBEMARLE | Elizabeth City | K31Z Food, Agriculture & Nutrition | $16.6M | 1 |
| Crisis Assistance Ministry | Charlotte | P60Z Human Services | $16.6M | 6 |
| Anuvia Prevention and Recovery Center Inc | Charlotte | — | $16.6M | 7 |
| PPRC NURSING HOME INC | High Point | E91 Health Care | $16.5M | 2 |
| GREATER RALEIGH AREA CHRISTIAN | Raleigh | B20Z Education | $16.5M | 2 |
| INTERNATIONAL SOCIETY OF AUTOMATION | Research Triangle Park | U030 Science & Technology | $16.5M | 8 |
| HOSPICE OF LAURENS COUNTY INC | Charlotte | P74Z Human Services | $16.5M | 10 |
| INSIGHT HUMAN SERVICES INC | Winstonsalem | F200 Mental Health & Crisis Intervention | $16.4M | 3 |
| PHOENIX ACADEMY INC | High Point | B11 Education | $16.4M | 0 |
| NORTH CAROLINA VETERINARY MEDICAL | Raleigh | B115 Education | $16.4M | 3 |
| PARTNERSHIP FOR CHILDREN OF | Fayetteville | B012 Education | $16.3M | 1 |
| Lake Junaluska Assembly Inc | Lake Junaluska | X99 Religion-Related | $16.3M | 2 |
| DUKE SCHOOL | Durham | — | $16.2M | 4 |
