| THE CANNON FOUNDATION INC | Concord | — | $20.4M | 9 |
| GASTON DAY SCHOOL INC | Gastonia | B200 Education | $20.4M | 2 |
| MOUNTAIN CREDIT UNION | Waynesville | — | $20.4M | 5 |
| CAPITAL AREA SOCCER LEAGUE INC | Raleigh | — | $20.4M | 6 |
| MASONIC AND EASTERN STAR HOME | Greensboro | P750 Human Services | $20.4M | 3 |
| NORTH CAROLINA MUSEUM OF ART FOUNDATION | Raleigh | A110 Arts, Culture & Humanities | $20.3M | 5 |
| STATE EMPLOYEES CREDIT UNION FOUNDATION | Raleigh | T23 Philanthropy, Voluntarism & Grantmaking Foundations | $20.3M | 0 |
| Nourish Up | Charlotte | P600 Human Services | $20.2M | 3 |
| NORTH CAROLINA CENTRAL UNIVERSITY | Durham | B110 Education | $20.1M | 1 |
| CHARLOTTE RESCUE MISSION | Charlotte | F220 Mental Health & Crisis Intervention | $20.1M | 2 |
| MYERS PARK COUNTRY CLUB INC | Charlotte | N50 Recreation & Sports | $20.1M | 0 |
| GIVING WITH GRACE FOUNDATION | Cornelius | — | $20M | 0 |
| COMMUNITY FOUNDATION OF HENDERSON | Hendersonville | T310 Philanthropy, Voluntarism & Grantmaking Foundations | $20M | 2 |
| EMPLOYMENT SOURCE INC | Fayetteville | P82 Human Services | $20M | 12 |
| HIGH COUNTRY COMMUNITY HEALTH INC | Boone | E30 Health Care | $19.8M | 13 |
| BIBLE BROADCASTING NETWORK INCORPORATED | Charlotte | X840 Religion-Related | $19.7M | 7 |
| MOVEMENT CHARTER SCHOOL | Charlotte | B29 Education | $19.7M | 3 |
| Lowes Foundation | Mooresville | B12 Education | $19.6M | 2 |
| CAROLINA COUNTRY CLUB COMPANY | Raleigh | — | $19.5M | 9 |
| SOUTHLIGHT HEALTHCARE INC | Raleigh | F20Z Mental Health & Crisis Intervention | $19.5M | 13 |
| COMMUNITY SCHOOL OF DAVIDSON INC | Davidson | B29 Education | $19.4M | 3 |
| FFTC PARTNERS FOR EMPOWERING COMMUNITIES | Charlotte | S31 Community Improvement & Capacity Building | $19.3M | 4 |
| Cape Fear Tutoring Inc | Wilmington | — | $19.2M | 4 |
| CENTRAL PIEDMONT COMMUNITY COLLEGE | Charlotte | B110 Education | $19.1M | 3 |
| PIEDMONT COMMUNITY CHARTER SCHOOL | Gastonia | B24 Education | $19.1M | 1 |
| MOUNTAIN PROJECTS INC | Waynesville | — | $19M | 1 |
| COMMUNITY INVESTMENTS FOUNDATION | Charlotte | P117 Human Services | $19M | 8 |
| NORTH RALEIGH CHRISTIAN ACADEMY INC | Raleigh | B99Z Education | $19M | 2 |
| RB TERRY CHARITABLE FOUNDATION INC | High Point | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $18.9M | 6 |
| THE CEDARS OF CHAPEL HILL CLUB INC | Chapel Hill | P80 Human Services | $18.9M | 0 |
| Carolina University | Winstonsalem | B40 Education | $18.8M | 5 |
| CABARRUS ROWAN COMMUNITY HEALTH CENTERS INC | Concord | E32 Health Care | $18.8M | 11 |
| Reinvestment Partners | Durham | S99Z Community Improvement & Capacity Building | $18.7M | 2 |
| EAST CAROLINA UNIVERSITY FOUNDATION INC | Greenville | B110 Education | $18.6M | 3 |
| PROCTON FAMILY FOUNDATION | Greensboro | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $18.5M | 0 |
| Bradford Preparatory School | Charlotte | B29 Education | $18.5M | 4 |
| Samaritan Housing Foundation Inc | Cary | P75 Human Services | $18.5M | 14 |
| VOYAGER ACADEMY INC | Durham | B29 Education | $18.4M | 3 |
| Lutheran Home - Hickory Inc | Salisbury | — | $18.4M | 5 |
| NATIONAL BOARD FOR CERTIFIED | Greensboro | — | $18.3M | 7 |
| THE GAMBRELL FOUNDATION | Charlotte | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $18.3M | 4 |
| CHRIST SCHOOL INC | Arden | B250 Education | $18.3M | 5 |
| NCHSAA FOUNDATION INC | Chapel Hill | N12 Recreation & Sports | $18.3M | 0 |
| Young Men's Christian Association | Greensboro | P27Z Human Services | $18.2M | 3 |
| BONNIE CONE CLASSICAL ACADEMY INC | Huntersville | B29 Education | $18.2M | 0 |
| TRIANGLE LAND CONSERVANCY INC | Durham | C340 Environment | $18.2M | 1 |
| CAROLINA SENIORCARE | Newton | E50 Health Care | $18.2M | 8 |
| CHARLES A CANNON TRUST NO 1 | Concord | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $18.2M | 5 |
| TRIANGLE CHARTER EDUCATION | Cary | B29 Education | $18.2M | 0 |
| THE FRANKLIN ACADEMY INC | Wake Forest | B24 Education | $18.1M | 1 |
