| CENTER FOR COMMUNITY RESOURCES INC | Butler | E70 Health Care | $28.6M | 2 |
| HOPE ENTERPRISES INC | Williamsport | P820 Human Services | $28.6M | 4 |
| COLUMBUS PROPERTY MANAGEMENT AND DEVELOPMENT INC | Philadelphia | L20 Housing & Shelter | $28.6M | 10 |
| LAWRENCE COUNTY SOCIAL SERVICES INC | New Castle | P20 Human Services | $28.6M | 5 |
| CHILDREN'S CENTER FOR TREATMENT AND EDUCATION | Bradford | Z99Z Unknown | $28.5M | 5 |
| UNITED WAY OF THE GREATER LEHIGH VALLEY | Allentown | T70 Philanthropy, Voluntarism & Grantmaking Foundations | $28.5M | 8 |
| COMMUNITY LEGAL SERVICES INC | Philadelphia | I80Z Crime & Legal-Related | $28.5M | 7 |
| Horizon House Developmental Services Inc | Philadelphia | P73Z Human Services | $28.5M | 6 |
| GOODWILL INDUSTRIES OF NC PA INC | Falls Creek | — | $28.5M | 0 |
| BLUEPRINTS | Washington | S200 Community Improvement & Capacity Building | $28.3M | 7 |
| Catholic Social Services | Philadelphia | — | $28.2M | 7 |
| SOMERSET RURAL ELECTRIC COOP INC | Somerset | — | $28.2M | 14 |
| ABINGTON HEALTH FOUNDATION | Philadelphia | E110 Health Care | $28.1M | 1 |
| LAKESIDE YOUTH SERVICE | North Wales | P300 Human Services | $28.1M | 5 |
| SARAH SCAIFE FOUNDATION INCORPORATED | Pittsburgh | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $28M | 10 |
| Iron Workers Welfare Plan of Western PA | Pittsburgh | — | $28M | 0 |
| THE ENVIRONMENTAL CHARTER SCHOOL AT FRICK PARK | Pittsburgh | B29 Education | $27.9M | 6 |
| Propel Schools Inc | Pittsburgh | B29 Education | $27.9M | 17 |
| BRICKLAYERS AND ALLIED CRAFTWORKERS LOCAL 1 PA/DE HEALTH & WELFARE FUND | Philadelphia | Y43 Mutual & Membership Benefit | $27.8M | 6 |
| LIFE ST MARY | Trevose | E30 Health Care | $27.7M | 17 |
| COMMUNITY FOUNDATION OF WESTERN PENNSYLVANIA AND EASTERN OHIO | Sharon | T310 Philanthropy, Voluntarism & Grantmaking Foundations | $27.7M | 2 |
| ALLEGHENY FOUNDATION | Pittsburgh | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $27.5M | 4 |
| PHILADELPHIA CRICKET CLUB | Philadelphia | — | $27.5M | 8 |
| SOUDERTON MENNONITE HOMES | Souderton | — | $27.4M | 8 |
| Granite State Electric Co Post Ret Bnft Niagra Mohawk Represented Health VEBA | Pittsburgh | — | $27.4M | 1 |
| ERIE COUNTY CARE MANAGEMENT INC | Erie | F32 Mental Health & Crisis Intervention | $27.3M | 2 |
| LANKENAU MEDICAL CENTER FOUNDATION | Wynnewood | E112 Health Care | $27.3M | 9 |
| FOXDALE VILLAGE CORPORATION | State College | P75Z Human Services | $27.3M | 7 |
| FRANKLIN TOWNE CHARTER HIGH SCHOOL | Philadelphia | B20 Education | $27.3M | 8 |
| THE PRESBYTERIAN FOUNDATION FOR PHILADELPHIA | Philadelphia | E110 Health Care | $27.2M | 3 |
| Granite State Co Post Ret Ben For EES Not Subject To Collective Bargaining Agrmnt | Pittsburgh | — | $27.2M | 1 |
| LEBANON VALLEY BRETHREN HOME | Palmyra | — | $27.2M | 8 |
| SCHOOL LANE CHARTER SCHOOL | Bensalem | B20Z Education | $27.2M | 6 |
| JENNER'S POND INC | Bala Cynwyd | E220 Health Care | $27.1M | 8 |
| DIAKON CHILD FAMILY & COMMUNITY MINISTRIES | Topton | — | $27.1M | 3 |
| UNITED STATES STEEL CORPORATION LEGACY RETIREE INSURANCE BENEFITS TRUST | Pittsburgh | Y43 Mutual & Membership Benefit | $27M | 0 |
| UNITED WAY OF GREATER PHILADELPHIA AND SOUTHERN NEW JERSEY | Philadelphia | T700 Philanthropy, Voluntarism & Grantmaking Foundations | $27M | 13 |
| ACHIEVEMENT HOUSE CHARTER SCHOOL | Exton | B29 Education | $27M | 4 |
| Esperanza Health Center Inc | Philadelphia | E320 Health Care | $27M | 10 |
| SPECTRUM HEALTH SERVICES INC | Philadelphia | E70Z Health Care | $27M | 14 |
| FAMILY DESIGN RESOURCES INC | Camp Hill | P40 Human Services | $26.9M | 1 |
| CHOP Clinical Associates Inc | Philadelphia | E030 Health Care | $26.8M | 4 |
| ASPIRA BILINGUAL CYBER CHARTER SCHOOL AN ASPIRA INC OF PENNSYLVANIA SCHOOL | Philadelphia | B29 Education | $26.8M | 2 |
| CARING COMMUNITY HEALTH CENTER | Wilkesbarre | E32 Health Care | $26.7M | 4 |
| SAUCON VALLEY COUNTRY CLUB | Bethlehem | — | $26.7M | 7 |
| THE BARNES FOUNDATION | Philadelphia | A510 Arts, Culture & Humanities | $26.7M | 9 |
| PAUL G BENEDUM JR FOUNDATION C/O DONNA B JOHNSON | Pittsburgh | T22Z Philanthropy, Voluntarism & Grantmaking Foundations | $26.6M | 1 |
| MCCUNE FOUNDATION PNC BANK NA | Pittsburgh | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $26.6M | 1 |
| THE EDUCATION CENTER AT THE WATSON INSTITUTE | Sewickley | B280 Education | $26.5M | 6 |
| HOLY FAMILY INSTITUTE | Pittsburgh | P400 Human Services | $26.5M | 5 |
