| PENNSYLVANIA PUBLIC EMPLOYEES COUNCIL 13 AFSCME | Harrisburg | — | $26.4M | 30 |
| EASTER SEALS OF SOUTHEASTERN PA | Philadelphia | E50Z Health Care | $26.4M | 7 |
| KIPP PHILADELPHA CHARTER SCHOOL | Philadelphia | B21 Education | $26.4M | 7 |
| Private Industry Council Inc | Greensburg | J20Z Employment | $26.4M | 3 |
| MEDICAL TRUST | Philadelphia | — | $26.4M | 1 |
| TRWIB INC | Pittsburgh | S30 Community Improvement & Capacity Building | $26.3M | 5 |
| THE PENNSYLVANIA BALLET ASSOCIATION DBA PHILADELPHIA BALLET | Philadelphia | A630 Arts, Culture & Humanities | $26.2M | 7 |
| PENNSYLVANIA DISTANCE LEARNING CHARTER SCHOOL | Sewickley | B29 Education | $26.2M | 7 |
| VINCENTIAN HOME | Pittsburgh | E910 Health Care | $26.2M | 6 |
| MERAKEY PHILADELPHIA | Lafayette Hill | F320 Mental Health & Crisis Intervention | $26.2M | 9 |
| TEAMSTERS LOCAL UNIONS 401 AND 773 HEALTH PLAN | Wilkesbarre | — | $26.2M | 1 |
| SOCIETY OF CHARTERED PROPERTY AND CASUALTY UNDERWRITERS | Malvern | — | $26.2M | 3 |
| ALLEGHENY CONFERENCE ON COMMUNITY DEVELOPMENT | Pittsburgh | — | $26.2M | 9 |
| FAIRMOUNT PARK CONSERVANCY | Philadelphia | C50 Environment | $26.1M | 6 |
| PENNSYLVANIA PSYCHIATRIC INSTITUTE | Hershey | E24 Health Care | $26.1M | 17 |
| THE FRED ROGERS COMPANY | Pittsburgh | A300 Arts, Culture & Humanities | $26.1M | 8 |
| North Penn Comprehensive Health Services | Mansfield | — | $26.1M | 8 |
| EXECUTIVE EDUCATION ACADEMY CHARTER SCHOOL | Allentown | B20 Education | $26M | 3 |
| JEFFERSON HEALTH CORPORATION F/K/A ALBERT EINSTEIN HEALTHCARE NETWORK | Philadelphia | E120 Health Care | $25.9M | 0 |
| PHILADELPHIA CITY FUND INC | Philadelphia | S33Z Community Improvement & Capacity Building | $25.9M | 1 |
| FAIRMOUNT HOMES | Ephrata | E91Z Health Care | $25.8M | 10 |
| CONNELLY FOUNDATION | West Conshohocken | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $25.7M | 12 |
| THE MS HERSHEY FOUNDATION | Hershey | T300 Philanthropy, Voluntarism & Grantmaking Foundations | $25.7M | 9 |
| THE FOUNDATION FOR INDIANA UNIVERSITY OF PENNSYLVANIA (IUP) | Indiana | B110 Education | $25.5M | 2 |
| NEXCUS INTERNATIONAL | Lancaster | Q33 International, Foreign Affairs & National Security | $25.4M | 3 |
| UNITED FOOD AND COMMERCIAL WORKERS H&W FUND OF NORTHEASTERN PENNSYLVANIA | Plymouth Meeting | — | $25.4M | 2 |
| CREATIVE HEALTH SERVICES INC | Pottstown | E21Z Health Care | $25.3M | 7 |
| Concern - Professional Services For Children Youth & Families | Fleetwood | P30Z Human Services | $25.3M | 5 |
| ELRC4KIDS INC | Latrobe | P20 Human Services | $25.2M | 1 |
| GIRL SCOUTS OF EASTERN PENNSYLVANIA INC | Miquon | O420 Youth Development | $25.2M | 7 |
| TRPIL COMMUNITY SERVICES | Washington | E92 Health Care | $25.2M | 2 |
| PHILADELPHIA CHARTER SCHOOL FOR ARTS AND SCIENCES AT HR EDMUNDS | Philadelphia | B20 Education | $25.2M | 6 |
| RENAISSANCE ACADEMY CHARTER SCHOOL | Phoenixville | B29 Education | $25.1M | 5 |
| ADAGIO HEALTH INC | Pittsburgh | E400 Health Care | $25.1M | 8 |
| EMERGYCARE INC | Erie | E62Z Health Care | $25.1M | 8 |
| FEEDING PENNSYLVANIA | Lemoyne | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $25M | 2 |
| OPPORTUNITY FINANCE NETWORK | Philadelphia | W60 Public & Societal Benefit | $25M | 15 |
| LAKESHORE COMMUNITY SERVICES INC | Erie | P20Z Human Services | $24.9M | 7 |
| CURTIS INSTITUTE OF MUSIC | Philadelphia | A6E0 Arts, Culture & Humanities | $24.9M | 14 |
| CARELINK COMMUNITY SUPPORT SERVICES PA | Media | F31Z Mental Health & Crisis Intervention | $24.9M | 7 |
| GROVE MANOR | Grove City | E91Z Health Care | $24.9M | 2 |
| THE CHILDREN'S INSTITUTE OF PITTSBURGH | Pittsburgh | B28 Education | $24.9M | 7 |
| WESBURY UNITED METHODIST COMMUNITY | Meadville | E910 Health Care | $24.9M | 7 |
| WILLIAMSON COLLEGE OF THE TRADES | Media | B300 Education | $24.8M | 6 |
| KEYSTONE COLLEGE | La Plume | B41Z Education | $24.8M | 3 |
| Esperanza Cyber Charter School | Philadelphia | B29 Education | $24.8M | 3 |
| EDITH L TREES TW CHAR TR ART X | Pittsburgh | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $24.7M | 2 |
| ARTHUR N RUPE FOUNDATION | West Chester | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $24.7M | 2 |
| ENERGY COORDINATING AGENCY OF PHILADELPHIA INC | Philadelhia | L820 Housing & Shelter | $24.7M | 4 |
| EDEN HALL FOUNDATION | Pittsburgh | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $24.6M | 7 |