| Mount Prospect Academy | Plymouth | B20 Education | $54.6M | 13 |
| Granite State Credit Union | Manchester | — | $48.9M | 9 |
| Colby-Sawyer College | New London | B420 Education | $48M | 7 |
| MOORE CENTER SERVICES INC | Manchester | P730 Human Services | $47M | 6 |
| NFI NORTH INC | Contoocook | P300 Human Services | $46.2M | 7 |
| Behavioral Health & Developmental Services of Strafford County Inc | Dover | — | $43.4M | 7 |
| Cottage Hospital | Woodsville | E220 Health Care | $42.7M | 12 |
| The Mental Health Center of Greater Manchester Inc | Manchester | — | $42.3M | 10 |
| Granite VNA Inc | Concord | E92Z Health Care | $42.2M | 8 |
| KENDAL AT HANOVER I | Hanover | L22 Housing & Shelter | $42.1M | 9 |
| Elliot Physican Network | Manchester | E30 Health Care | $41.7M | 12 |
| TRIANGLE CREDIT UNION | Nashua | — | $41.7M | 11 |
| Advanced Regenerative Manufacturing Institute Inc | Manchester | S41 Community Improvement & Capacity Building | $41.5M | 6 |
| SOUTHERN NEW HAMPSHIRE SERVICES INC | Manchester | P200 Human Services | $40.9M | 3 |
| NORTHERN HUMAN SERVICES INC | Conway | P800 Human Services | $40.5M | 7 |
| Dartmouth-Hitchcock Health | Lebanon | E02 Health Care | $40.2M | 11 |
| Concord Hospital - Franklin | Concord | E20 Health Care | $40M | 10 |
| Harbor Homes Inc | Nashua | L21Z Housing & Shelter | $39.7M | 8 |
| PROCTOR ACADEMY | Andover | B250 Education | $38.8M | 6 |
| UNIVERSITY OF NEW HAMPSHIRE FOUNDATION INCORPORATED | Durham | B110 Education | $38.5M | 9 |
| Jaffe Foundation | Portsmouth | T21J Philanthropy, Voluntarism & Grantmaking Foundations | $36.5M | 0 |
| UPPER CONNECTICUT VALLEY HOSPITAL | Colebrook | E22Z Health Care | $36.3M | 11 |
| RIVERBEND COMMUNITY MENTAL HEALTH | Concord | — | $36.1M | 7 |
| NEW HAMPSHIRE LIFE AND HEALTH INSURANCE GUARANTY ASSOCIATION | Bedford | — | $35.2M | 1 |
| Bellwether Community Credit Union | Manchester | — | $33.4M | 9 |
| SPAULDING ACADEMY & FAMILY SERVICES | Northfield | F33Z Mental Health & Crisis Intervention | $32.7M | 7 |
| NORTH COUNTRY HEALTHCARE INC | Whitefield | E01 Health Care | $32.5M | 14 |
| KIMBALL UNION ACADEMY | Meriden | B250 Education | $31.6M | 6 |
| Brewster Academy | Wolfeboro | B250 Education | $31M | 8 |
| PETERBOROUGH RETIREMENT COMMUNITY AT UPLAND FARM INC | Peterborough | P750 Human Services | $30.8M | 7 |
| United Church of Christ Retirement Community Inc | Concord | P750 Human Services | $30.4M | 7 |
| COMMUNITY ACTION PROGRAM BELKNAP-MERRIMACK COUNTIES INC | Concord | P200 Human Services | $30.2M | 3 |
| THE NEW HAMPTON SCHOOL | New Hampton | B250 Education | $30M | 5 |
| Catholic Medical Center Physicians Practice Associates | Manchester | E22Z Health Care | $30M | 12 |
| Gateways Community Services Inc | Nashua | — | $29.8M | 2 |
| Community Bridges Inc | Concord | P700 Human Services | $29.3M | 7 |
| The Mental Health Center for Southern New Hampshire Inc | Derry | — | $29M | 11 |
| GRANITE STATE INDEPENDENT LIVING | Concord | P8XZ Human Services | $28.4M | 4 |
| NEW HAMPSHIRE PUBLIC DEFENDER | Concord | — | $28.2M | 12 |
| HOLDERNESS SCHOOL | Plymouth | B250 Education | $27.2M | 10 |
| NORTH MAIN STREET FUND | Concord | S01 Community Improvement & Capacity Building | $27.1M | 0 |
| TAYLOR COMMUNITY | Laconia | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $26.9M | 2 |
| The Granite Young Men's Christian Association | Manchester | — | $26.5M | 5 |
| SEACOAST MENTAL HEALTH CENTER INC | Portsmouth | F30Z Mental Health & Crisis Intervention | $26.4M | 7 |
| Lamprey Health Care Inc | Newmarket | E320 Health Care | $24.7M | 9 |
| Amoskeag Health | Manchester | E32Z Health Care | $24.7M | 10 |
| Home Health and Hospice Care | Merrimack | E99Z Health Care | $24.5M | 9 |
| Cheshire Health Foundation | Keene | E110 Health Care | $24.3M | 8 |
| CARDIGAN MOUNTAIN SCHOOL | Canaan | B240 Education | $24.3M | 7 |
| LAKES REGION COMMUNITY SERVICES COUNCIL INC | Laconia | P820 Human Services | $24.1M | 2 |
