| CAPITAL GROUP COMPANIES CHARITABLE | Irvine | T20Z Philanthropy, Voluntarism & Grantmaking Foundations | $52.7M | 0 |
| ROBERT LOUIS STEVENSON SCHOOL | Pebble Beach | B200 Education | $52.7M | 12 |
| LIFE CHIROPRACTIC COLLEGE WEST | Hayward | B500 Education | $52.7M | 12 |
| REVOLUTIONARY MEDICAL TRUST | Pasadena | — | $52.6M | 0 |
| NORTHERN CALIFORNIA INSTITUTE FOR | San Francisco | H00Z Medical Research | $52.6M | 8 |
| TOSA FOUNDATION | Portola Valley | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $52.6M | 1 |
| CAMINAR | San Mateo | F31Z Mental Health & Crisis Intervention | $52.5M | 12 |
| WILDLIFE CONSERVATION NETWORK INC | San Francisco | D30 Animal-Related | $52.5M | 7 |
| SECOND HARVEST OF THE GREATER VALLEY | Manteca | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $52.4M | 1 |
| KINGS COMMUNITY ACTION ORGANIZATION INC | Hanford | P20Z Human Services | $52.3M | 6 |
| COMMUNICARE HEALTH CENTERS | Davis | — | $52.3M | 12 |
| South County Community Health Center Inc | East Palo Alto | E32 Health Care | $52.2M | 11 |
| WOODBURY UNIVERSITY | Burbank | B430 Education | $52.1M | 15 |
| DREW CHILD DEVELOPMENT CORPORATION | Gardena | P37Z Human Services | $52M | 2 |
| KEDREN COMMUNITY HEALTH CENTERINC | Los Angeles | F320 Mental Health & Crisis Intervention | $52M | 13 |
| THE MARISLA FOUNDATION | Laguna Beach | — | $52M | 3 |
| AMERICAN CONSERVATORY THEATRE FOUNDATION | San Francisco | A650 Arts, Culture & Humanities | $51.9M | 12 |
| PARA LOS NINOS | Los Angeles | P300 Human Services | $51.9M | 8 |
| MEN'S HEALTH FOUNDATION | Los Angeles | E30 Health Care | $51.8M | 11 |
| ELECTRICAL WORKERS HEALTH AND WELFARE | San Francisco | — | $51.7M | 0 |
| THE PALMDALE AEROSPACE ACADEMY | Palmdale | B29 Education | $51.6M | 6 |
| SPECIALTY EQUIPMENT MARKET ASSOCIATION & | Diamond Bar | — | $51.6M | 11 |
| SOUTHLAND CREDIT UNION | Los Alamitos | — | $51.6M | 8 |
| BAY AREA AUTOMOTIVE GROUP WELFARE FUND | Dublin | — | $51.5M | 0 |
| SBCS CORPORATION | Chula Vista | P200 Human Services | $51.5M | 9 |
| OPTIONS FOR YOUTH - DUARTE INC | Pasadena | B29 Education | $51.4M | 5 |
| EVERY ORG | San Francisco | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $51.4M | 3 |
| PRICE PHILANTHROPIES FOUNDATION | La Jolla | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $51.4M | 3 |
| MEMORIALCARE SELECT HEALTH PLAN | Fountain Valley | E21 Health Care | $51.3M | 10 |
| INNER CITY EDUCATION FOUNDATION | Los Angeles | B25Z Education | $51.3M | 8 |
| FLEXTECH ALLIANCE INC | San Jose | — | $51.3M | 8 |
| HOMEFIRST SERVICES OF SANTA CLARA COUNTY | Milpitas | — | $51.2M | 6 |
| MANIFEST MEDEX | Riverside | E02 Health Care | $51.1M | 11 |
| PACIFIC CHARTER INSTITUTE INC | Sacramento | B29 Education | $50.9M | 16 |
| JONI AND FRIENDS | Agoura Hills | — | $50.9M | 9 |
| ROBERT H MURPHY FOUNDATION | Santa Ana | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $50.9M | 0 |
| EDNOVATE INC | Los Angeles | B20 Education | $50.7M | 10 |
| GOLDEN GATE NATIONAL PARKS CONSERVANCY | San Francisco | C110 Environment | $50.7M | 15 |
| WASHINGTON TOWNSHIP MEDICAL FOUNDATION | Fremont | E31 Health Care | $50.7M | 10 |
| Los Angeles Centers for Alcohol and Drug | Santa Fe Springs | — | $50.6M | 7 |
| ILEAD CALIFORNIA CHARTERS 1 | Acton | B11 Education | $50.5M | 7 |
| UDW AFSCME 3930 RIVERSIDE COUNTY | San Diego | Y43 Mutual & Membership Benefit | $50.4M | 1 |
| MIND OC | Irvine | P20 Human Services | $50.4M | 11 |
| COMMUNITY FOUNDATION SANTA CRUZ | Aptos | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $50.4M | 5 |
| REAL JOURNEY ACADEMIES | Ontario | B29 Education | $50.4M | 7 |
| SOUTH CENTRAL FAMILY HEALTH CENTER | Los Angeles | E32Z Health Care | $50.2M | 12 |
| UFW FOUNDATION | Los Angeles | — | $50.1M | 7 |
| AMERICAN FIRST CREDIT UNION | Brea | — | $50.1M | 11 |
| GOLDEN GLOBE FOUNDATION | West Hollywood | A12 Arts, Culture & Humanities | $50.1M | 0 |
| PROVIDENCE HEALTH & SERVICES FOUNDATION | Burbank | E112 Health Care | $50.1M | 5 |
