| MESA DEVELOPMENTAL SERVICES | Grand Junction | P820 Human Services | $16.2M | 2 |
| P3 FOUNDATION INC | Denver | P20 Human Services | $16.1M | 1 |
| USA CYCLING INC | Colorado Springs | N11 Recreation & Sports | $16M | 11 |
| Bromley East Charter School | Brighton | B29 Education | $16M | 5 |
| MERCY HOUSING NORTHWEST | Denver | — | $16M | 7 |
| TELLURIDE MOUNTAIN VILLAGE OWNERS | Mountain Village | — | $16M | 1 |
| A PRECIOUS CHILD INC | Broomfield | P30 Human Services | $15.9M | 4 |
| COLORADO MESA UNIVERSITY FOUNDATION | Grand Junciton | B110 Education | $15.9M | 0 |
| United States Fencing Association | Colorado Springs | N71 Recreation & Sports | $15.8M | 8 |
| NORTHWEST COLORADO VISITING NURSE ASSOCIATION | Steamboat Springs | E920 Health Care | $15.8M | 9 |
| COLORADO BALLET | Denver | A630 Arts, Culture & Humanities | $15.7M | 4 |
| FLATIRONS ACADEMY | Westminster | B24 Education | $15.5M | 3 |
| UNITED STATES OF AMERICA | Glendale | — | $15.5M | 9 |
| Lotus School for Excellence | Aurora | — | $15.4M | 10 |
| GAMMA PHI BETA SORORITY INC | Centennial | — | $15.4M | 6 |
| GLOBAL VILLAGE ACADEMY AURORA | Aurora | B29 Education | $15.4M | 0 |
| Colorado Springs Independence Center | Colorado Springs | P800 Human Services | $15.4M | 4 |
| MCREL INTERNATIONAL | Denver | — | $15.3M | 8 |
| COLORADO EDUCATION ASSOCIATION | Denver | — | $15.3M | 12 |
| Colorado Laborers Health and Welfare | Aurora | — | $15.3M | 0 |
| STANLEY BRITISH PRIMARY SCHOOL | Denver | B24Z Education | $15.2M | 6 |
| NEIGHBOR TO NEIGHBOR INC | Fort Collins | L800 Housing & Shelter | $15.1M | 2 |
| BAYAUD ENTERPRISES INC | Denver | J330 Employment | $15.1M | 2 |
| AMG CHARITABLE GIFT FOUNDATION | Greenwood Village | T300 Philanthropy, Voluntarism & Grantmaking Foundations | $15M | 2 |
| Leman Classical School | Parker | B29 Education | $15M | 1 |
| COMFORT BRIDGE DBA CARE SYNERGY | Denver | E02 Health Care | $15M | 11 |
| WESTERN CONSERVATION FOUNDATION | Denver | C30 Environment | $15M | 5 |
| PIKES PEAK HOSPICE AND PALLIATIVE | Denver | — | $15M | 7 |
| Rocky Mountain Youth Medical and Nursing | Thornton | E99 Health Care | $14.9M | 7 |
| Monument Academy | Monument | B29 Education | $14.9M | 1 |
| MILE HIGH COUNCIL ON ALCOHOLISM AND | Aurora | F21Z Mental Health & Crisis Intervention | $14.9M | 7 |
| DENVER CHRISTIAN SCHOOLS | Lakewood | B24Z Education | $14.8M | 2 |
| Metro Caring | Denver | — | $14.8M | 4 |
| Engineering Ministries International USA | Colorado Springs | U42 Science & Technology | $14.7M | 7 |
| The Springs Rescue Mission | Colorado Springs | P20 Human Services | $14.7M | 5 |
| ENVIRONMENT AMERICA INC | Denver | C30 Environment | $14.6M | 4 |
| Craig Hospital Foundation | Englewood | E22 Health Care | $14.5M | 7 |
| VAIL HEALTH SERVICES FOUNDATION | Vail | E12 Health Care | $14.5M | 2 |
| Youth for ChristUSA Inc | Englewood | O55Z Youth Development | $14.4M | 7 |
| ACSI Children Education Fund Inc | Colorado Springs | P20 Human Services | $14.4M | 2 |
| MORRIS ANIMAL FOUNDATION | Denver | D050 Animal-Related | $14.4M | 11 |
| PINEHURST COUNTRY CLUB | Denver | N50 Recreation & Sports | $14.3M | 7 |
| DENVER ATHLETIC CLUB | Denver | — | $14.2M | 7 |
| STEADMAN PHILIPPON RESEARCH INSTITUTE | Vail | H92 Medical Research | $14.2M | 7 |
| GREATER COLORADO COUNCIL | Denver | O410 Youth Development | $14.1M | 5 |
| POLICING EQUITY | Denver | R01 Civil Rights, Social Action & Advocacy | $14.1M | 9 |
| ASPEN VIEW ACADEMY | Castle Rock | B29 Education | $14.1M | 0 |
| Youth for Christ International Ministries | Parker | X20Z Religion-Related | $14.1M | 3 |
| JEFFCO ACTION CENTER INC | Lakewood | Z99Z Unknown | $14.1M | 2 |
| ST ANNE'S EPISCOPAL SCHOOL INC | Denver | — | $14M | 9 |
