| Ascent Classical Academy | Golden | B29 Education | $18.8M | 0 |
| URBAN LAND CONSERVANCY | Denver | S20 Community Improvement & Capacity Building | $18.8M | 8 |
| INVESTMENT MANAGEMENT CONSULTANTS | Greenwood Village | — | $18.7M | 10 |
| SANGRE DE CRISTO HOSPICE & PALLIATIVE CARE | Pueblo | P74Z Human Services | $18.6M | 9 |
| SOCIETY FOR MINING METALLURGY & | Englewood | U30C Science & Technology | $18.6M | 8 |
| UNIVERSITY LICENSE EQUITY HOLDINGS INC | Aurora | U20 Science & Technology | $18.6M | 4 |
| UNITED FOOD AND COMMERCIAL WORKERS | Wheat Ridge | — | $18.5M | 33 |
| FLATIRON CONSTRUCTION CORP | Broomfield | — | $18.4M | 3 |
| Vanguard Classical School Inc | Aurora | B29 Education | $18.3M | 2 |
| VAIL VALLEY FOUNDATION | Avon | S410 Community Improvement & Capacity Building | $18.3M | 10 |
| SkyView Academy | Highlands Ranch | B29 Education | $18.3M | 2 |
| FOUNTAIN VALLEY SCHOOL OF COLORADO | Colorado Springs | B250 Education | $18.1M | 5 |
| INTERNATIONAL SCHOOL OF DENVER | Denver | B60 Education | $17.9M | 4 |
| San Luis Valley Community Mental Health | Alamosa | E21 Health Care | $17.9M | 7 |
| SAVIO HOUSE | Denver | P32 Human Services | $17.8M | 4 |
| OneChild Global | Colorado Springs | Q330 International, Foreign Affairs & National Security | $17.8M | 6 |
| ENERGY RESOURCE CENTER | Colorado Springs | L810 Housing & Shelter | $17.7M | 3 |
| COLORADO FUSION SOCCER CLUB INC | Aurora | N60Z Recreation & Sports | $17.7M | 4 |
| PROSPERITY DENVER FUND | Denver | B82 Education | $17.7M | 1 |
| CENTENNIAL MENTAL HEALTH CENTER | Sterling | — | $17.6M | 6 |
| OLATHE COMMUNITY CLINIC INC | Olathe | E32 Health Care | $17.6M | 7 |
| Liberty Common School | Fort Collins | B29 Education | $17.6M | 8 |
| ASPEN COMMUNITY FOUNDATION | Basalt | T310 Philanthropy, Voluntarism & Grantmaking Foundations | $17.5M | 4 |
| VAIL MOUNTAIN SCHOOL | Vail | B24Z Education | $17.5M | 7 |
| UNITE AMERICA INSTITUTE INC | Denver | W01 Public & Societal Benefit | $17.5M | 0 |
| LATINO COMMUNITY FOUNDATION OF COLORADO | Denver | A23 Arts, Culture & Humanities | $17.4M | 1 |
| Banning Lewis Ranch Academy | Colorado Springs | B29 Education | $17.4M | 0 |
| KATHERINE AND CHARLES HOVER GREEN HOUSES | Longmont | — | $17.3M | 0 |
| USA HOCKEY FOUNDATION | Colorado Springs | — | $17.3M | 3 |
| CHRISTIAN LIVING COMMUNITIES | Englewood | L22 Housing & Shelter | $17.3M | 12 |
| AVENTA CREDIT UNION | Colorado Springs | — | $17.2M | 15 |
| USA Triathlon of Colorado | Colorado Springs | N71 Recreation & Sports | $17.1M | 12 |
| ASPEN ART MUSEUM | Aspen | A510 Arts, Culture & Humanities | $17M | 2 |
| DENVER COUNTRY CLUB | Denver | — | $16.9M | 9 |
| CATHOLIC HEALTH INITIATIVES COLORADO | Centennial | E110 Health Care | $16.9M | 6 |
| NATIONAL BOARD OF CHIROPRACTIC EXAMINERS | Greeley | — | $16.8M | 21 |
| TRI COUNTY HOUSING INC | Fowler | L800 Housing & Shelter | $16.8M | 1 |
| COLORADO WEST PSYCHIATRIC HOSPITAL INC | Grand Junction | F31 Mental Health & Crisis Intervention | $16.8M | 0 |
| UC HEALTH LABORATORY SERVICES | Denver | E80 Health Care | $16.7M | 3 |
| MILE HIGH MONTESSORI EARLY LEARNING CENT | Denver | — | $16.6M | 6 |
| BRIDGES TO PROSPERITY INC | Greenwood Village | Q30 International, Foreign Affairs & National Security | $16.6M | 5 |
| MERCY COMMUNITY CAPITAL | Denver | L20 Housing & Shelter | $16.5M | 8 |
| DENVER SCHOLARSHIP FOUNDATION | Denver | B99 Education | $16.5M | 8 |
| MOORE IMPACT INC | Denver | P20 Human Services | $16.5M | 7 |
| GIRL SCOUTS OF COLORADO | Denver | O42 Youth Development | $16.4M | 11 |
| OWEESTA CORPORATION | Longmont | S20 Community Improvement & Capacity Building | $16.4M | 7 |
| CAREERWISE COLORADO | Denver | B02 Education | $16.4M | 11 |
| EBEN EZER LUTHERAN CARE CENTER | Brush | E90Z Health Care | $16.4M | 2 |
| INTERNATIONAL ASSOCIATION OF | Boulder | S41 Community Improvement & Capacity Building | $16.2M | 11 |
| English Language Institute in China | Fort Collins | Q300 International, Foreign Affairs & National Security | $16.2M | 5 |
