| Charleston Hospital Inc | Charleston | — | $43.7M | 10 |
| West Virginia University Medical Corp | Charleston | B99 Education | $42M | 13 |
| WVUHS Home Care LLC | Morgantown | — | $40.4M | 11 |
| International Union of Operating | Huntington | — | $39.9M | 0 |
| Wetzel County Hospital Inc | New Martinsville | E22 Health Care | $39.2M | 9 |
| WEST VIRGINIA HEALTH RIGHT INC | Charleston | — | $37.8M | 6 |
| WOMENCARE INC | Scott Depot | E32Z Health Care | $37.5M | 8 |
| Northwood Health System | Wheeling | F320 Mental Health & Crisis Intervention | $37.4M | 3 |
| MARYLAND ELECTRICAL INDUSTRY HEALTH FUND | Ona | — | $36.9M | 0 |
| LINCOLN COUNTY PRIMARY CARE CENTER INC | Hamlin | E320 Health Care | $36.6M | 7 |
| GOODWILL INDUSTRIES OF KANAWHA VALLEY | Charleston | — | $36.5M | 4 |
| WEST VIRGINIA LABORERS' TRUST FUND | Charleston | — | $36.5M | 1 |
| SHENANDOAH VALLEY MEDICAL SYSTEM I | Martinsburg | E39Z Health Care | $36.5M | 8 |
| BETHANY COLLEGE | Bethany | B420 Education | $34.1M | 4 |
| E A HAWSE HEALTH CENTER | Baker | E300 Health Care | $33.8M | 7 |
| New River Health Association Inc | Oak Hill | E320 Health Care | $33.5M | 8 |
| CIVIL-MILITARY INNOVATION | Morgantown | V05 Social Science | $33.3M | 9 |
| CAMC PLATEAU MEDICAL CENTER INC | Charleston | E22 Health Care | $33.1M | 8 |
| MONTGOMERY GENERAL HOSPITAL INC | Montgomery | E22Z Health Care | $32.3M | 17 |
| RAINELLE MEDICAL CENTER INC | Rainelle | E32Z Health Care | $32.2M | 7 |
| WELTY HOME FOR THE AGED INC | Wheeling | P75I Human Services | $31.8M | 6 |
| Braxton County Memorial Hospital Inc | Gassaway | E22Z Health Care | $31.7M | 14 |
| THE CHILDREN'S HOME SOCIETY OF WEST | Charleston | P30Z Human Services | $31.7M | 2 |
| ANN SONNEBORN CHARITABLE FOUNDATION | Wheeling | T90 Philanthropy, Voluntarism & Grantmaking Foundations | $31.3M | 0 |
| MINNIE HAMILTON HEALTH CARE CENTER INC | Grantsville | E22 Health Care | $31.3M | 7 |
| RIVER VALLEY CHILD DEVELOPMENT | Huntington | P33Z Human Services | $29.9M | 2 |
| Employer-Teamsters Local Nos 175 & 505 | Charleston | — | $29.7M | 0 |
| QUALITY INSIGHTS INC | Charleston | — | $29.4M | 19 |
| WESTBROOK HEALTH SERVICES INC | Parkersburg | F20Z Mental Health & Crisis Intervention | $29.3M | 8 |
| MARIETTA MEMORIAL HOSPITAL | Sistersville | E20 Health Care | $29.1M | 10 |
| Wheeling Jesuit University Inc | Wheeling | B430 Education | $28.9M | 3 |
| CORTLAND ACRES ASSOCIATION INC | Thomas | P750 Human Services | $28M | 3 |
| CABIN CREEK HEALTH CENTER INC | Dawes | X00Z Religion-Related | $27.4M | 8 |
| UNITED FOOD & COMMERICIAL WORKERS LOCAL | South Charleston | — | $27.1M | 0 |
| HIGHLAND-CLARKSBURG HOSPITAL INC | Clarksburg | E22 Health Care | $27M | 11 |
| THE GREATER KANAWHA VALLEY FOUNDATION | Charleston | T310 Philanthropy, Voluntarism & Grantmaking Foundations | $26.8M | 2 |
| KANAWHA HOSPICE CARE INC | Charleston | P74Z Human Services | $26.8M | 7 |
| SOUTHERN HIGHLANDS COMMUNITY | Princeton | — | $26.2M | 7 |
| MYLAN PARK FOUNDATION INC | Morgantown | B112 Education | $25.5M | 2 |
| TRI-COUNTY BUILDING TRADES HEALTH FUND | Ona | — | $25.4M | 0 |
| SOUTHWEST LMC | Ona | N62 Recreation & Sports | $25.2M | 0 |
| COALFIELD DEVELOPMENT CORPORATION | Wayne | L99 Housing & Shelter | $23.4M | 5 |
| CHANGE INC | Weirton | J20Z Employment | $22.9M | 9 |
| VALLEY HEALTH CARE INC | Mill Creek | Z99Z Unknown | $22.6M | 8 |
| FACING HUNGER FOODBANK INC | Huntington | — | $22.3M | 0 |
| MARSHALL UNIVERSITY FOUNDATION INCORPORATED | Huntington | B110 Education | $22.2M | 3 |
| BROADDUS HOSPITAL ASSOCIATION INC | Philippi | E220 Health Care | $22.2M | 8 |
| PARTNER COMMUNITY CAPITAL INC | Charles Town | P20 Human Services | $21.7M | 8 |
| CARPENTERS HEALTH FUND OF WEST VIRGINIA | Ona | — | $21.6M | 0 |
| ELKINS REGIONAL CONVALESCENT CENTER INC | Elkins | E91Z Health Care | $21M | 3 |
