| THE HERITAGE FOUNDATION | Washington | W050 Public & Societal Benefit | $133.9M | 12 |
| CAPITAL AREA FOOD BANK INC | Washington | K310 Food, Agriculture & Nutrition | $132.9M | 13 |
| NATIONAL IAM BENEFIT TRUST FUND | Washington | — | $131.4M | 7 |
| AMERICAN FEDERATION OF LABOR AND CONGRESS OF INDUSTRIAL ORGANIZATIONS | Washington | — | $131.2M | 14 |
| PAN AMERICAN DEVELOPMENT FOUNDATION | Washington | Q300 International, Foreign Affairs & National Security | $131.1M | 12 |
| AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE | Washington | U030 Science & Technology | $129.5M | 14 |
| MAJORITY FORWARD | Washington | — | $127.8M | 2 |
| JUDICIAL WATCH INC | Washington | W00M Public & Societal Benefit | $127.7M | 9 |
| INTERNATIONAL REPUBLICAN INSTITUTE | Washington | B80 Education | $126.5M | 8 |
| INTERNATIONAL FOOD POLICY RESEARCH INSTITUTE | Washington | K050 Food, Agriculture & Nutrition | $126M | 19 |
| The Urban Institute | Washington | V340 Social Science | $124.7M | 9 |
| UNITED BROTHERHOOD OF CARPENTERS AND JOINERS OF AMERICA | Washington | — | $124.3M | 14 |
| American College of Cardiology Foundation | Washington | G43Z Diseases, Disorders & Medical Disciplines | $124.2M | 35 |
| FRIENDS OF THE WORLD FOOD PROGRAM INC | Washington | P20 Human Services | $122.1M | 9 |
| AMERICAN ASSOCIATION OF STATE HIGHWAY AND TRANSPORTATION OFFICIALS | Washington | S41Z Community Improvement & Capacity Building | $121.6M | 11 |
| UNITED PALESTINIAN APPEAL INC | Washington | Q330 International, Foreign Affairs & National Security | $120.7M | 3 |
| Our American Future Foundation | Washington | R40 Civil Rights, Social Action & Advocacy | $120.3M | 0 |
| PATHFINDER INTERNATIONAL | Washington | Q300 International, Foreign Affairs & National Security | $119.9M | 13 |
| AMERICAN SOCIETY OF HEMATOLOGY INC | Washington | G43Z Diseases, Disorders & Medical Disciplines | $118.7M | 12 |
| National Restaurant Association | Washington | — | $116.5M | 14 |
| AMERICAN COUNCILS FOR INTERNATIONAL EDUCATION ACTR ACCELS INC | Washington | Q220 International, Foreign Affairs & National Security | $113.9M | 12 |
| BIOTECHNOLOGY INNOVATION ORGANIZATION | Washington | — | $113.8M | 8 |
| NORTH AMERICAN ELECTRIC RELIABILITY CORP | Washington | S41 Community Improvement & Capacity Building | $112.4M | 27 |
| THE HALO TRUST (USA) INC | Washington | Q330 International, Foreign Affairs & National Security | $112M | 3 |
| LABORERS' INTERNATIONAL UNION OF NORTH AMERICA | Washington | — | $111M | 28 |
| THE BROOKINGS INSTITUTION | Washington | V220 Social Science | $109M | 20 |
| INTERNATIONAL UNION OF OPERATING ENGINEERS | Washington | — | $107.4M | 31 |
| AMERICAN BEVERAGE ASSOCIATION | Washington | — | $106.1M | 9 |
| CTIA - THE WIRELESS ASSOCIATION | Washington | — | $104.3M | 15 |
| NATIONAL TRUST FOR HISTORIC PRESERVATION IN THE UNITED STATES | Washington | A800 Arts, Culture & Humanities | $104.1M | 16 |
| CREDIT UNION NATIONAL ASSOCIATION INC | Washington | S41 Community Improvement & Capacity Building | $103.9M | 14 |
| NATIONAL COMMITTEE FOR QUALITY ASSURANCE | Washington | E31D Health Care | $103.1M | 14 |
| CHILDREN'S RESEARCH INSTITUTE | Washington | H98Z Medical Research | $102.1M | 10 |
| NATIONAL ASSOCIATION OF COUNTY AND CITY HEALTH OFFICALS | Washington | Z99Z Unknown | $101.9M | 7 |
| INTERNATIONAL ASSOCIATION OF SHEET METAL AIR RAIL AND TRANSPORTATION WORKERS | Washington | J40 Employment | $100.3M | 46 |
| BUILDING AMERICA'S FUTURE | Washington | R01 Civil Rights, Social Action & Advocacy | $100.2M | 4 |
| Greater Washington Community Foundation | Washington | T310 Philanthropy, Voluntarism & Grantmaking Foundations | $100M | 9 |
| CONFERENCE OF STATE BANK SUPERVISORS | Washington | W19 Public & Societal Benefit | $97.6M | 12 |
| EDISON ELECTRIC INSTITUTE INC | Washington | S41 Community Improvement & Capacity Building | $96M | 21 |
| SOUNDEXCHANGE INC | Washington | S40 Community Improvement & Capacity Building | $95.2M | 9 |
| Mary's Center for Maternal and Child Care Inc | Washington | — | $94.3M | 14 |
| THE URBAN LAND INSTITUTE | Washington | C340 Environment | $93.1M | 18 |
| FIRST BOOK | Washington | B92Z Education | $92.3M | 12 |
| GLOBALGIVING FOUNDATION INC | Washington | Q112 International, Foreign Affairs & National Security | $91.1M | 12 |
| FREEDOM HOUSE | Washington | Q700 International, Foreign Affairs & National Security | $90.3M | 23 |
| BRICK BY BRICK FOUNDATION | Washington | — | $88.8M | 0 |
| Thurgood Marshall College Fund | Washington | B82Z Education | $88.3M | 11 |
| United States Association for UNHCR | Washington | Q420 International, Foreign Affairs & National Security | $88M | 7 |
| United Mine Workers of America 1992 Benefit Plan | Washington | — | $87.8M | 5 |
| ACACIA CENTER FOR JUSTICE | Washington | P84 Human Services | $87.6M | 10 |
