| WEST TEXAS OPPORTUNITIES INC | Lamesa | P200 Human Services | $32.5M | 5 |
| Shannon Business Services Inc | San Angelo | E11 Health Care | $32.5M | 7 |
| AUSTIN THEATRE ALLIANCE | Austin | A65 Arts, Culture & Humanities | $32.5M | 7 |
| BARTON CREEK SENIOR LIVING CENTER INC | Dallas | L22 Housing & Shelter | $32.5M | 8 |
| CLARITY CHILD GUIDANCE CENTER | San Antonio | F31Z Mental Health & Crisis Intervention | $32.5M | 12 |
| LONE STAR COMMUNITY HEALTH CENTER | Conroe | E30 Health Care | $32.4M | 9 |
| Texas Health Urgent Care | Arlington | F30 Mental Health & Crisis Intervention | $32.4M | 14 |
| Texas Operators Association | Houston | Y43 Mutual & Membership Benefit | $32.3M | 0 |
| The Hubbard Trust | Celina | — | $32.3M | 1 |
| THE ASSOCIATION OF FORMER STUDENTS OF TEXAS A&M UNIVERSITY | College Station | B840 Education | $32.3M | 12 |
| DALLAS ARBORETUM AND BOTANICAL SOCIETY INC | Dallas | C410 Environment | $32.2M | 13 |
| Apartment Life Inc | Bedford | X20 Religion-Related | $32.2M | 10 |
| ADRIENNE DILLARD-COONS MEM FDN | Dallas | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $32.1M | 0 |
| Impetus Foundation | San Antonio | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $32.1M | 0 |
| DALLAS CONVENTION & VISITORS BUREAU | Dallas | — | $32.1M | 12 |
| ELECTRICAL MEDICAL TRUST | Houston | — | $31.9M | 0 |
| DOVETAIL IMPACT FOUNDATION (FKA DAVID WEEKLEY FAMILY FOUNDATION) | Houston | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $31.9M | 1 |
| The John G and Marie Stella Kenedy Memorial Foundation | Corpus Christi | X110 Religion-Related | $31.8M | 16 |
| EAST TEXAS BORDER HEALTH CLINIC GENESIS PRIMECARE | Marshall | E32 Health Care | $31.8M | 9 |
| SOUTHWEST CHRISTIAN SCHOOL INC | Fort Worth | B21Z Education | $31.8M | 5 |
| Houston Gateway Academy Inc | Houston | B29 Education | $31.8M | 8 |
| CHRISTUS NORTHEAST TEXAS AND NORTHERN LOUISIANA HEALTH SYSTEM CORPORATION | Irving | X00Z Religion-Related | $31.6M | 17 |
| REGENTS SCHOOL OF AUSTIN INC | Austin | B200 Education | $31.5M | 7 |
| TEXAS FARM BUREAU | Waco | — | $31.4M | 37 |
| Eula Mae and John Baugh Foundation | San Antonio | T22J Philanthropy, Voluntarism & Grantmaking Foundations | $31.4M | 1 |
| Frio Hospital Association | Pearsall | E220 Health Care | $31.3M | 5 |
| COMP-U-DOPT INC | Houston | B99 Education | $31.3M | 6 |
| TING TSUNG & WEI FONG CHAO FOUNDATION | Houston | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $31.2M | 0 |
| Liberty Educational Ministries Inc | Argyle | X20Z Religion-Related | $31.1M | 5 |
| LAMB COUNTY ELECTRIC COOPERATIVE INC | Littlefield | — | $31.1M | 14 |
| GARDENIA FOUNDATION | Houston | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $31M | 0 |
| SOUTHWEST TEXAS ELECTRIC COOPERATIVE INC | Eldorado | — | $31M | 14 |
| TARRANT COUNTY SENIOR LIVING CENTER INC | Dallas | L220 Housing & Shelter | $31M | 11 |
| WORKFORCE SOLUTIONS SOUTHEAST TEXAS | Beaumont | P20 Human Services | $30.9M | 3 |
| Hildebrand Foundation | Houston | T21 Philanthropy, Voluntarism & Grantmaking Foundations | $30.9M | 0 |
| SOCIETY OF ST VINCENT DE PAUL CHARITABLE PHARMACY OF NORTH TEXAS | Dallas | E60 Health Care | $30.7M | 2 |
| HUMAN COALITION | Plano | P45 Human Services | $30.7M | 8 |
| SAN ANTONIO LIGHTHOUSE FOR THE BLIND | San Antonio | P860 Human Services | $30.7M | 8 |
| CARILLON INC | Lubbock | P750 Human Services | $30.7M | 0 |
| COMMUNITY FOUNDATION OF ABILENE | Abilene | T310 Philanthropy, Voluntarism & Grantmaking Foundations | $30.6M | 1 |
| Houston Grand Opera Association Inc | Houston | A6A0 Arts, Culture & Humanities | $30.4M | 12 |
| The Terry Foundation | Houston | B82Z Education | $30.4M | 3 |
| EX-STUDENTS' ASSOCIATION OF UT | Austin | B840 Education | $30.4M | 8 |
| FORT BEND FAMILY HEALTH CENTER INC | Richmond | E320 Health Care | $30.3M | 33 |
| VISIT SAN ANTONIO INC | San Antonio | S41 Community Improvement & Capacity Building | $30.2M | 13 |
| BENT TREE COUNTRY CLUB INC | Dallas | — | $30.1M | 10 |
| DISABILITY SERVICES OF THE SOUTHWEST INC | San Antonio | P80Z Human Services | $30M | 11 |
| THE COMMEMORATIVE AIR FORCE | Dallas | A50 Arts, Culture & Humanities | $30M | 8 |
| BAKER & MCKENZIE VEBA MEDICAL PLAN | Dallas | — | $29.9M | 1 |
| NATIONAL BREAST CANCER FOUNDATION INC | Frisco | E70M Health Care | $29.9M | 9 |
