| CARILLON INC | Lubbock | P750 Human Services | $30.7M | 0 |
| CLARITY CHILD GUIDANCE CENTER | San Antonio | F31Z Mental Health & Crisis Intervention | $30.6M | 12 |
| COASTAL BEND FOOD BANK | Corpus Christi | K310 Food, Agriculture & Nutrition | $30.6M | 1 |
| REMINGTON COLLEGE | Dallas | B42 Education | $30.6M | 8 |
| COMMUNITY FOUNDATION OF ABILENE | Abilene | T310 Philanthropy, Voluntarism & Grantmaking Foundations | $30.6M | 1 |
| Menil Foundation Inc | Houston | A51 Arts, Culture & Humanities | $30.5M | 7 |
| Houston Grand Opera Association Inc | Houston | A6A0 Arts, Culture & Humanities | $30.4M | 12 |
| The Terry Foundation | Houston | B82Z Education | $30.4M | 3 |
| BUCKNER SENIOR LIVING INC | Dallas | L22 Housing & Shelter | $30.4M | 12 |
| VISIT SAN ANTONIO INC | San Antonio | S41 Community Improvement & Capacity Building | $30.2M | 13 |
| DOVETAIL IMPACT FOUNDATION | Houston | — | $30.1M | 1 |
| SOLDIERS' ANGELS | San Antonio | M20 Public Safety, Disaster Preparedness & Relief | $30.1M | 5 |
| DISABILITY SERVICES OF THE | San Antonio | P80Z Human Services | $30M | 11 |
| NATIONAL BREAST CANCER FOUNDATION INC | Frisco | E70M Health Care | $29.9M | 9 |
| LOS BARRIOS UNIDOS COMMUNITY CLINIC INC | Dallas | — | $29.9M | 14 |
| Nueces County MHMR Community Center | Corpus Christi | F30Z Mental Health & Crisis Intervention | $29.9M | 4 |
| EASTER SEALS OF GREATER HOUSTON INC | Houston | G23Z Diseases, Disorders & Medical Disciplines | $29.9M | 7 |
| JEROLD B KATZ FOUNDATION | Houston | — | $29.8M | 0 |
| SOUTHWESTERN EXPOSITION | Fort Worth | K260 Food, Agriculture & Nutrition | $29.8M | 63 |
| Valley Baptist Legacy Foundation | Harlingen | E12 Health Care | $29.8M | 2 |
| Remember the Alamo Foundation | San Antonio | A56 Arts, Culture & Humanities | $29.7M | 2 |
| SWISHER ELECTRIC COOPERATIVE INC | Tulia | — | $29.7M | 10 |
| Marketplace Ministries Inc | Plano | X20Z Religion-Related | $29.7M | 4 |
| GULF COAST COMMUNITY SERVICES | Houston | S200 Community Improvement & Capacity Building | $29.6M | 5 |
| BARTON CREEK SENIOR LIVING CENTER INC | Dallas | L22 Housing & Shelter | $29.6M | 8 |
| Texas Children's Urgent Care | Bellaire | E21 Health Care | $29.6M | 17 |
| The Woodlands Christian Academy | The Woodlands | — | $29.6M | 7 |
| Meadows Foundation Inc | Dallas | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $29.6M | 21 |
| BST SENIOR LIVING WEST INC | San Antonio | — | $29.6M | 9 |
| Mercury One Inc | Irving | Q33 International, Foreign Affairs & National Security | $29.6M | 4 |
| HUMAN COALITION | Plano | P45 Human Services | $29.5M | 9 |
| BUCKINGHAM SENIOR LIVING COMMUNITY INC | Houston | P75 Human Services | $29.5M | 10 |
| TRINITY SCHOOL OF MIDLAND TEXAS | Midland | B21Z Education | $29.5M | 4 |
| The Brookwood Community Inc | Brookshire | B280 Education | $29.5M | 7 |
| HUSTON-TILLOTSON UNIVERSITY | Austin | — | $29.5M | 5 |
| CoastLife Credit Union | Corpus Christi | — | $29.3M | 4 |
| THE SAFE ALLIANCE | Austin | — | $29.1M | 7 |
| Jewish Federation of Greater Houston | Houston | — | $29.1M | 7 |
| Community Healthcare of Texas | Fort Worth | P74 Human Services | $29.1M | 7 |
| DALLAS CENTER FOR THE PERFORMING ARTS | Dallas | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $28.9M | 7 |
| RAINWATER CHARITABLE FOUNDATION | Fort Worth | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $28.9M | 8 |
| The Rees-Jones Foundation | Dallas | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $28.9M | 3 |
| DALLAS SYMPHONY FOUNDATION | Dallas | A11 Arts, Culture & Humanities | $28.9M | 0 |
| FORT BEND FAMILY HEALTH CENTER INC | Richmond | E320 Health Care | $28.8M | 24 |
| TOYOTA MOTOR SALES USA INC | Plano | Y43 Mutual & Membership Benefit | $28.8M | 1 |
| Broughton Foundation Trust | Dallas | — | $28.8M | 4 |
| GREATER EAST TEXAS | Nacogdoches | — | $28.8M | 2 |
| JEWISH FAMILY SERVICE OF DALLAS INC | Dallas | P28Z Human Services | $28.7M | 5 |
| TEXAS PUBLIC POLICY FOUNDATION | Austin | W06Z Public & Societal Benefit | $28.7M | 15 |
| CENTRO DE SALUD FAMILIAR LA FE INC | El Paso | E320 Health Care | $28.7M | 10 |