| BRAZOS VALLEY COMMUNITY ACTION AGENCY INC | College Station | P20Z Human Services | $34.8M | 13 |
| BORDER REGION MHMR COMMUNITY CENTER | Laredo | F30 Mental Health & Crisis Intervention | $34.8M | 3 |
| LEDUCQ FOUNDATION FOR CARDIOVASCULAR RESEARCH | Houston | H43 Medical Research | $34.8M | 0 |
| BCFS Health and Human Services | San Antonio | P70Z Human Services | $34.7M | 12 |
| AUSTIN AFFORDABLE HOUSING CORPORATION | Austin | L20 Housing & Shelter | $34.7M | 0 |
| TRINITY VALLEY SCHOOL | Fort Worth | B200 Education | $34.6M | 7 |
| THE FONDREN FOUNDATION | Houston | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $34.6M | 0 |
| ASIAN AMERICAN HEALTH COALITION OF THE GREATER HOUSTON AREA | Houston | E70 Health Care | $34.6M | 8 |
| LUKE AND LORI MORROW FAMILY FOUNDATION | McKinney | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $34.6M | 0 |
| DALLAS COUNTRY CLUB | Dallas | — | $34.6M | 5 |
| EL CAMPO MEMORIAL HOSPITAL | El Campo | E20 Health Care | $34.6M | 10 |
| THE LEGACY MIDTOWN PARK INC | Dallas | L22 Housing & Shelter | $34.5M | 9 |
| GOODWILL INDUSTRIES OF SOUTH TEXAS INC | Corpus Christi | — | $34.5M | 8 |
| HOSPICE AUSTIN | Austin | P74Z Human Services | $34.4M | 8 |
| NORTH PLAINS ELECTRIC COOPERATIVE INC | Perryton | — | $34.2M | 17 |
| PETCO LOVE | San Antonio | T123 Philanthropy, Voluntarism & Grantmaking Foundations | $34.2M | 0 |
| SU CLINICA FAMILIAR INC | Harlingen | E320 Health Care | $34.2M | 8 |
| LEGAL AID OF NORTHWEST TEXAS | Fort Worth | I83Z Crime & Legal-Related | $34.2M | 6 |
| DALLAS ZOO MANAGEMENT INC | Dallas | D11 Animal-Related | $34.1M | 10 |
| COMMIT2DALLAS | Dallas | B05 Education | $34M | 11 |
| The Hobby Center Foundation | Houston | A116 Arts, Culture & Humanities | $34M | 7 |
| SOUTHWESTERN EXPOSITION AND LIVESTOCK SHOW | Fort Worth | K260 Food, Agriculture & Nutrition | $34M | 61 |
| HOUSING AND COMMUNITY SERVICES INC | San Antonio | L200 Housing & Shelter | $34M | 7 |
| SAN PATRICIO ELECTRIC COOPERATIVE INC | Sinton | — | $33.9M | 18 |
| PIPE FITTERS LOCAL UNION #211 WELFARE TRUST FUND | Houston | — | $33.9M | 1 |
| Belknap Ministries Inc | Dallas | X20 Religion-Related | $33.9M | 0 |
| SAN ANTONIO COUNTRY CLUB | San Antonio | N50 Recreation & Sports | $33.9M | 7 |
| CENTRAL TEXAS REGIONAL WATER SUPPLY CORPORATION | San Antonio | — | $33.8M | 3 |
| PANHANDLE COMMUNITY SERVICES | Amarillo | P120 Human Services | $33.8M | 2 |
| MEADOW OAKS EDUCATION FOUNDATION | Mesquite | B12 Education | $33.8M | 1 |
| TEXTILE EXCHANGE | Lamesa | K20 Food, Agriculture & Nutrition | $33.5M | 7 |
| VISITING NURSE ASSOCIATION OF TEXAS | Dallas | E92Z Health Care | $33.5M | 5 |
| BAILEY COUNTY ELECTRIC COOPERATIVE ASSOCIATION | Muleshoe | — | $33.4M | 13 |
| BARBERS HILL ISD EDUCATION FOUNDATION | Mont Belvieu | B11 Education | $33.4M | 0 |
| Houston Jewish Community Foundation | Houston | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $33.4M | 2 |
| LIONHEART CHILDREN'S ACADEMY | Bedford | X20 Religion-Related | $33.4M | 10 |
| THE HOLDSWORTH CENTER | Austin | T40 Philanthropy, Voluntarism & Grantmaking Foundations | $33.2M | 12 |
| THE PRESBYTERIAN NIGHT SHELTER OF TARRANT COUNTY | Fort Worth | L41Z Housing & Shelter | $32.9M | 7 |
| COASTAL BEND FOOD BANK | Corpus Christi | K310 Food, Agriculture & Nutrition | $32.9M | 1 |
| The Cullen Trust for the Performing Arts | Houston | A126 Arts, Culture & Humanities | $32.9M | 0 |
| MANOR PARK INC | Midland | P750 Human Services | $32.8M | 8 |
| SLAVONIC BENEVOLENT ORDER OF THE STATE OF TEXAS | Temple | — | $32.7M | 12 |
| TEXAS EXCAVATION SAFETY SYSTEM INC | Richardson | — | $32.7M | 29 |
| THE WILLIAM STAMPS FARISH FUND | Houston | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $32.7M | 2 |
| Family Service Association of San Antonio Inc | San Antonio | P400 Human Services | $32.7M | 5 |
| NATIONAL CUTTING HORSE ASSOCIATION | Fort Worth | — | $32.7M | 6 |
| REFUGEE & IMMIGRANT CENTER FOR EDUCATION & LEGAL SERVICES | San Antonio | R21Z Civil Rights, Social Action & Advocacy | $32.6M | 9 |
| SOLDIERS' ANGELS | San Antonio | M20 Public Safety, Disaster Preparedness & Relief | $32.6M | 3 |
| PEORIA INDUSTRIAL INC | Dallas | — | $32.6M | 0 |
| AMERICAN ASSOCIATION OF NURSE PRACTITIONERS | Austin | — | $32.5M | 12 |
