| HONOR CREDIT UNION | Berrien Springs | — | $127.9M | 10 |
| WESTERN MICHIGAN UNIVERSITY HOMER STRYKER MD SCHOOL OF MEDICINE | Kalamazoo | B50 Education | $125.6M | 9 |
| CREDIT UNION CHARTERED IN THE STATE OF COMMUNITY CHOICE CREDIT UNION | Farmington Hills | — | $124.8M | 17 |
| ELGA CREDIT UNION | Grand Blanc | — | $123.1M | 11 |
| PHYSICIANS HEALTH NETWORK | East Lansing | E300 Health Care | $121.3M | 18 |
| MSU HEALTH CARE INC | East Lansing | E30 Health Care | $120.4M | 18 |
| MCLAREN MEDICAL GROUP | Flint | E300 Health Care | $120.1M | 12 |
| DAVENPORT UNIVERSITY | Grand Rapids | B420 Education | $119.1M | 10 |
| ORGAN PROCUREMENT AGENCY OF MICHIGAN | Ann Arbor | — | $117.9M | 12 |
| DOW CREDIT UNION | Midland | — | $117.1M | 11 |
| MICHIGAN HEALTH ENDOWMENT FUND | Brighton | G12 Diseases, Disorders & Medical Disciplines | $116.1M | 11 |
| GLEANERS COMMUNITY FOOD BANK OF SOUTHEASTERN MICHIGAN | Detroit | K31 Food, Agriculture & Nutrition | $116.1M | 11 |
| MCLAREN HEALTH MANAGEMENT GROUP | Davison | E32 Health Care | $114.2M | 10 |
| MYMICHIGAN MEDICAL CENTER CLARE | Clare | — | $112.7M | 10 |
| VAN ANDEL RESEARCH INSTITUTE | Grand Rapids | H300 Medical Research | $112.7M | 15 |
| WAYNE-METROPOLITAN COMMUNITY ACTION AGENCY INC | Detroit | S200 Community Improvement & Capacity Building | $112.2M | 10 |
| PENSKE FOUNDATION INC | Bloomfield Hills | T21 Philanthropy, Voluntarism & Grantmaking Foundations | $108.7M | 0 |
| UNIVERSITY PEDIATRICIANS | Detroit | E31 Health Care | $108.3M | 12 |
| COMMUNITY FINANCIAL CREDIT UNION | Plymouth | — | $106.7M | 13 |
| DETROIT AREA AGENCY ON AGING | Detroit | P81Z Human Services | $105M | 7 |
| SAMARITAS | Detroit | P200 Human Services | $104M | 10 |
| FORGOTTEN HARVEST INC | Oak Park | K31M Food, Agriculture & Nutrition | $101.8M | 13 |
| ANDREWS UNIVERSITY | Berrien Springs | B430 Education | $101.7M | 11 |
| THE DETROIT INSTITUTE OF ARTS | Detroit | A510 Arts, Culture & Humanities | $100.8M | 11 |
| ADRIAN COLLEGE | Adrian | B420 Education | $100.8M | 7 |
| ALBION COLLEGE | Albion | B420 Education | $100.6M | 13 |
| MHT HOUSING INC | Bingham Farms | L200 Housing & Shelter | $99.4M | 8 |
| W E UPJOHN UNEMPLOYMENT TRUSTEE CORP | Kalamazoo | J220 Employment | $98.3M | 11 |
| MUNSON HEALTHCARE GRAYLING | Traverse City | E20 Health Care | $97.9M | 16 |
| HILLS & DALES GENERAL HOSPITAL INC | Cass City | E220 Health Care | $96.7M | 8 |
| MICHIGAN LIFE AND HEALTH INSURANCE GUARANTY ASSOCIATION | Haslett | — | $94.9M | 0 |
| HELPING HAND FOR RELIEF AND DEVELOPMENT INC | Southfield | P60 Human Services | $94M | 7 |
| Bronson Lakeview Hospital | Kalamazoo | E20 Health Care | $94M | 16 |
| HILLSDALE COMMUNITY HEALTH CENTER | Hillsdale | E32Z Health Care | $93.8M | 8 |
| Wolverine Power Marketing Cooperative | Cadillac | Y22 Mutual & Membership Benefit | $93.7M | 7 |
| UNITED WAY FOR SOUTHEASTERN MICHIGAN | Detroit | M20 Public Safety, Disaster Preparedness & Relief | $93.1M | 9 |
| MACOMB-OAKLAND-REGIONAL CENTER INC | Clinton Township | P800 Human Services | $93.1M | 2 |
| MICHIGAN REGIONAL COUNCIL OF CARPENTERS' EMPLOYEE BENEFITS FUND | Troy | Y43 Mutual & Membership Benefit | $92.7M | 5 |
| LAWRENCE TECHNOLOGICAL UNIVERSITY | Southfield | B430 Education | $92.2M | 13 |
| COLLEGE FOR CREATIVE STUDIES | Detroit | B420 Education | $91.3M | 10 |
| UNIVERSITY OF MICHIGAN HEALTH MEDICARE | East Lansing | E70 Health Care | $91.2M | 14 |
| CLOVERLAND ELECTRIC COOPERATIVE | Sault Ste Marie | — | $90.7M | 17 |
| ALMA COLLEGE | Alma | B420 Education | $90.4M | 16 |
| FINANCIAL PLUS CREDIT UNION | Flint | — | $90.3M | 11 |
| CREDIT UNIONS CHARTERED IN THE STATE OF MICHIGAN | Ann Arbor | — | $89.5M | 12 |
| GREAT LAKES BAY HEALTH CENTERS | Saginaw | E320 Health Care | $89.4M | 16 |
| Holland Home | Grand Rapids | P70Z Human Services | $88.8M | 8 |
| Kettering University | Flint | B500 Education | $88.3M | 13 |
| TRINITY CONTINUING CARE SERVICES | Livonia | E910 Health Care | $88.2M | 13 |
| VIBE CREDIT UNION | Novi | — | $87.4M | 21 |
