| BERRIEN COMMUNITY FOUNDATION INC | St Joseph | T31Z Philanthropy, Voluntarism & Grantmaking Foundations | $22.7M | 2 |
| TRINITY HEALTH PACE | Livonia | — | $22.7M | 15 |
| BETHANY CHRISTIAN SERVICES | Grand Rapids | P400 Human Services | $22.6M | 0 |
| Presbyterian Village East | Chesterfield Twp | E91 Health Care | $22.6M | 7 |
| FOOD GATHERERS | Ann Arbor | — | $22.5M | 1 |
| MCBRIDE QUALITY CARE SERVICES INC | Mt Pleasant | P70Z Human Services | $22.5M | 2 |
| MIDMICHIGAN HEALTH SERVICES | Houghton Lake | E39Z Health Care | $22.4M | 14 |
| THE CASCADE PACE INC | Jackson | P81 Human Services | $22.3M | 10 |
| VALLEY AREA AGENCY ON AGING | Flint | — | $22.3M | 2 |
| SPARROW CARSON HOSPITAL | Carson City | E220 Health Care | $22.3M | 0 |
| MCLAREN CARO REGION | Caro | E220 Health Care | $22.2M | 8 |
| LOC CREDIT UNION | Farmington | — | $22.2M | 9 |
| MARY FREE BED ORTHOTICS AND PROSTHETICS | Grand Rapids | — | $22.1M | 11 |
| GREENHILLS SCHOOL | Ann Arbor | B25Z Education | $22.1M | 7 |
| MID MICHIGAN COMMUNITY ACTION | Farwell | — | $22M | 3 |
| LOCOMOTIVE ENGINEERS & CONDUCTORS MUTUAL PROTECTIVE ASSOCIATION | Southfield | — | $22M | 7 |
| THE SKILLMAN FOUNDATION | Detroit | B82 Education | $21.9M | 16 |
| UA Local 190 Health and Welfare Trust | Troy | — | $21.9M | 0 |
| THE MEIJER FOUNDATION | Grand Rapids | — | $21.8M | 2 |
| New Paradigm for Education Inc | Detroit | B90 Education | $21.8M | 6 |
| WAYNE STATE UNIVERSITY FOUNDATION | Detroit | B432 Education | $21.7M | 10 |
| DETROIT METRO CONVENTION AND | Detroit | — | $21.6M | 5 |
| World Renew | Byron Center | — | $21.6M | 1 |
| GRAND HAVEN AREA COMMUNITY | Grand Haven | T31Z Philanthropy, Voluntarism & Grantmaking Foundations | $21.5M | 4 |
| Michigan Physical Fitness Health | Lansing | E70 Health Care | $21.4M | 6 |
| INTERLOCHEN ARTS CAMP | Interlochen | A25 Arts, Culture & Humanities | $21.3M | 3 |
| CREDIT UNIONS CHARTERED IN THE STATE OF | Flint | — | $21.3M | 6 |
| MICHIGAN CHRISTIAN HOME | Grand Rapids | — | $21.3M | 5 |
| NEIGHBORHOOD SERVICE ORGANIZATION | Detroit | — | $21.3M | 9 |
| ANN ARBOR DISTRICT LIBRARY | Ann Arbor | B700 Education | $21.3M | 4 |
| COMMUNITY ACTION AGENCY OF SOUTH CENTRAL | Battle Creek | P20Z Human Services | $21.2M | 4 |
| EAST JORDAN FAMILY HEALTH CENTER | East Jordan | E39Z Health Care | $21.1M | 8 |
| PROBILITY THERAPY SERVICES | Ann Arbor | E50 Health Care | $21.1M | 8 |
| MOTT CHILDREN'S HEALTH CENTER | Flint | E320 Health Care | $21.1M | 7 |
| Training and Treatment Innovations | Oxford | P80 Human Services | $21.1M | 3 |
| THE CARLS FOUNDATION | Bloomfield Hills | T22Z Philanthropy, Voluntarism & Grantmaking Foundations | $21M | 7 |
| PACE North | Traverse City | E32 Health Care | $20.9M | 3 |
| MARIAN VILLAGE CORPORATION | Livonia | E91Z Health Care | $20.9M | 8 |
| MICHIGAN BEER & WINE WHOLESALERS | Lansing | — | $20.8M | 0 |
| Methodist Children's Home Society | Redford | P700 Human Services | $20.8M | 5 |
| College of Healthcare Information Management Executives | Ann Arbor | — | $20.8M | 14 |
| DETROIT OPERA | Detroit | A610 Arts, Culture & Humanities | $20.8M | 5 |
| Michigan Tech Fund | Houghton | B110 Education | $20.7M | 0 |
| RENAISSANCE COMMUNITY HOMES | Adrian | P730 Human Services | $20.7M | 1 |
| CENTERS FOR FAMILY DEVELOPMENT INC | Detroit | — | $20.6M | 5 |
| Michigan Saves | Lansing | C35 Environment | $20.6M | 0 |
| GRAND RAPIDS PUBLIC MUSEUM | Grand Rapids | A50 Arts, Culture & Humanities | $20.6M | 3 |
| WESTERN WAYNE FAMILY HEALTH CENTERS | Inkster | E32 Health Care | $20.4M | 9 |
| Arbor Research Collaborative for | Ann Arbor | H99Z Medical Research | $20.4M | 21 |
| IBEW LOCAL NO 150 WELFARE FUND | Lansing | — | $20.3M | 1 |
