| EXTRA CREDIT UNION | Warren | — | $26.1M | 8 |
| CANTERBURY HEALTH CARE INC | Waterford | P75 Human Services | $26M | 0 |
| SHEET METAL WORKERS LOCAL NO 80 INSURANCE TRUST | Troy | — | $26M | 4 |
| FAMILY MEDICAL CENTER OF | Temperance | F32Z Mental Health & Crisis Intervention | $25.9M | 7 |
| AMERICAN CONCRETE INSTITUTE | Farmington Hills | U30C Science & Technology | $25.9M | 7 |
| BAY HUMAN SERVICES | Standish | P73Z Human Services | $25.9M | 6 |
| GOODWILL INDUSTRIES OF NORTHERN | Traverse City | J32Z Employment | $25.8M | 4 |
| CINNAIRE CORPORATION | Lansing | L20 Housing & Shelter | $25.7M | 12 |
| Michiana Area Electrical Workers Health & Welfare | Lansing | — | $25.6M | 0 |
| ALUMNI ASSOCIATION OF THE UNIVERSITY OF MICHIGAN | Ann Arbor | B840 Education | $25.6M | 10 |
| OAKLAND INTEGRATED HEALTHCARE | Pontiac | E32 Health Care | $25.5M | 11 |
| BARBARA ANN KARMANOS CANCER INSTITUTE | Detroit | H30 Medical Research | $25.4M | 20 |
| PAUL OLIVER MEMORIAL HOSPITAL | Traverse City | E220 Health Care | $25.4M | 19 |
| YMCA of Metropolitan Detroit | Detroit | P270 Human Services | $25.3M | 7 |
| PACE Central Michigan | Mt Pleasant | E60 Health Care | $25.2M | 7 |
| SPECTRUM JUVENILE JUSTICE SERVICES | Westland | I72 Crime & Legal-Related | $25.2M | 1 |
| ADVENTURE CREDIT UNION | Grand Rapids | — | $25M | 9 |
| UNIVERSITY LIGGETT SCHOOL | Grosse Pointe Woods | B200 Education | $25M | 8 |
| 1199 CORNERSTONE COMMUNITY FINANCIAL | Auburn Hills | — | $24.9M | 12 |
| GREATER LANSING FOOD BANK | Lansing | K31Z Food, Agriculture & Nutrition | $24.8M | 1 |
| Rochester Christian University | Rochester Hills | — | $24.7M | 7 |
| Holland Christian Education Society | Holland | — | $24.7M | 3 |
| ANGELA HOSPICE HOME CARE INC | Livonia | P74Z Human Services | $24.6M | 9 |
| MARY FREE BED REHABILITATION HOSPITAL | Grand Rapids | E12 Health Care | $24.6M | 5 |
| MUNSON HOME CARE | Traverse City | E92 Health Care | $24.6M | 11 |
| ISABELLA CITIZENS FOR HEALTH INC | Mt Pleasant | E32 Health Care | $24.3M | 9 |
| UNITED WAY OF SOUTH CENTRAL MICHIGAN | Kalamazoo | T70Z Philanthropy, Voluntarism & Grantmaking Foundations | $24.3M | 5 |
| FRAUNHOFER USA INC | Plymouth | H99 Medical Research | $24.2M | 9 |
| COOK FAMILY FOUNDATION | Owosso | — | $24.1M | 1 |
| ALLIED MEDIA PROJECTS INC | Detroit | A02 Arts, Culture & Humanities | $24.1M | 9 |
| THE COMMUNITY FOUNDATION OF THE | Holland | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $24M | 3 |
| MICHIGAN VIRTUAL UNIVERSITY | Lansing | B300 Education | $24M | 8 |
| CLARK RETIREMENT COMMUNITY INC | Grand Rapids | L220 Housing & Shelter | $24M | 8 |
| SOUTH MICHIGAN FOOD BANK | Battle Creek | — | $23.9M | 1 |
| Credit Unions Chartered in the State of MI CASE Credit Union | Lansing | — | $23.8M | 8 |
| TRUENORTH COMMUNITY SERVICES | Fremont | P200 Human Services | $23.8M | 3 |
| REGION 3B AREA AGENCY ON AGING | Battle Creek | P810 Human Services | $23.7M | 2 |
| GRAND ACTION FOUNDATION 20 | Grand Rapids | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $23.6M | 1 |
| GESHER HUMAN SERVICES | Southfield | J30 Employment | $23.5M | 9 |
| AMERICAN BOARD OF EMERGENCY | East Lansing | — | $23.5M | 27 |
| Kellanova Salaried and Sales Employees' | Battle Creek | — | $23.4M | 0 |
| HENRY FORD PHYSICIAN PARTNERS | Detroit | E11 Health Care | $23.4M | 4 |
| Lakeland Immediate Care Center | Cassopolis | E32 Health Care | $23.2M | 9 |
| SPARTAN IMAGING INC | Lansing | E30 Health Care | $23.1M | 0 |
| RAHMA WORLDWIDE AID AND DEVELOPMENT | Beverly Hills | Q71 International, Foreign Affairs & National Security | $23M | 2 |
| THE ARBOR CIRCLE CORPORATION | Grand Rapids | P400 Human Services | $22.9M | 5 |
| GLACIER HILLS INC | Ann Arbor | P750 Human Services | $22.8M | 12 |
| JUDSON CENTER INC | Farmington Hills | P700 Human Services | $22.8M | 11 |
| DETROIT BELLE ISLE GRAND PRIX INC | Bloomfield Hills | S990 Community Improvement & Capacity Building | $22.8M | 1 |
| JAMIE AND DENISE JACOB FAMILY | Troy | O50 Youth Development | $22.7M | 0 |
