| ST FRANCIS REGIONAL MEDICAL CENTER | Minneapolis | E220 Health Care | $227.4M | 11 |
| PARK NICOLLET HEALTH SERVICES | St Louis Park | E210 Health Care | $226.5M | 20 |
| MACALESTER COLLEGE | St Paul | B420 Education | $224.7M | 15 |
| HAZELDEN BETTY FORD FOUNDATION | Center City | F200 Mental Health & Crisis Intervention | $219.7M | 25 |
| XCEL ENERGY INC VEBA FOR ACTIVE | Minneapolis | Y43 Mutual & Membership Benefit | $209.2M | 1 |
| CUYUNA REGIONAL MEDICAL CENTER | Crosby | E20 Health Care | $207.4M | 7 |
| FARM CREDIT FOUNDATIONS WELFARE BENEFITS | St Paul | — | $205.2M | 0 |
| ST PAUL TEACHERS RETIREMENT FUND ASSOCIATION | St Paul | Y33 Mutual & Membership Benefit | $203.4M | 1 |
| ANNE RAY FOUNDATION | Eden Prairie | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $198.4M | 14 |
| CONSUMER CHOICE SERVICES INC | Minnetonka | P44 Human Services | $188.4M | 6 |
| WORKERS' COMPENSATION REINSURANCE ASSOCIATION | St Paul | — | $188.2M | 20 |
| LAKEVIEW MEMORIAL HOSPITAL | Minneapolis | E220 Health Care | $186.5M | 23 |
| MINNESOTA LABORERS HEALTH AND WELFARE | Mendota Heights | — | $185.2M | 8 |
| LUTHERAN SOCIAL SERVICE OF MINNESOTA | St Paul | P200 Human Services | $180.7M | 12 |
| ACCRA CARE INC | Minnetonka | P44 Human Services | $179.7M | 6 |
| YOUNG MENS CHRISTIAN ASSOCIATION OF THE NORTH | Minneapolis | P27 Human Services | $173.8M | 10 |
| ST MARY'S REGIONAL HEALTH CENTER | Detroit Lakes | E220 Health Care | $172.9M | 9 |
| LAKE REGION HEALTHCARE CORPORATION | Fergus Falls | E220 Health Care | $168.5M | 12 |
| UNIVERSITY OF MINNESOTA HEALTH | Minneapolis | E24 Health Care | $167.3M | 0 |
| ECUMEN | Shoreview | — | $164.5M | 10 |
| LAKEWOOD HEALTH SYSTEM | Staples | E21Z Health Care | $162.9M | 25 |
| SAINT PAUL & MINNESOTA FOUNDATION | St Paul | T310 Philanthropy, Voluntarism & Grantmaking Foundations | $161M | 12 |
| Healtheast Medical Research Institute | Minneapolis | E050 Health Care | $158.4M | 17 |
| MEDICA COMMUNITY HEALTH PLAN | Minnetonka | E31 Health Care | $152.1M | 4 |
| MANKATO REHABILITATION CENTER INC | Mankato | J33Z Employment | $151.6M | 8 |
| MAGNIFI FINANCIAL CREDIT UNION | Melrose | — | $149.7M | 29 |
| ST CATHERINE UNIVERSITY | St Paul | B430 Education | $147.6M | 10 |
| THE MINNEAPOLIS FOUNDATION | Minneapolis | T310 Philanthropy, Voluntarism & Grantmaking Foundations | $146.9M | 10 |
| GUSTAVUS ADOLPHUS COLLEGE | Saint Peter | B420 Education | $145.9M | 11 |
| EAST CENTRAL ENERGY | Braham | — | $143.4M | 23 |
| SAINT JOHN'S UNIVERSITY | Collegeville | — | $140.3M | 10 |
| AUGSBURG UNIVERSITY | Minneapolis | B420 Education | $138.9M | 10 |
| Avera Marshall | Marshall | E20 Health Care | $138.6M | 10 |
| Range Regional Health Services | Hibbing | E220 Health Care | $134.7M | 15 |
| PIPE TRADES SERVICES MN WELFARE FUND | White Bear Lake | — | $127.8M | 0 |
| BETHEL UNIVERSITY | St Paul | B420 Education | $127.1M | 9 |
| WELIA HEALTH | Mora | E21 Health Care | $125.2M | 13 |
| WRIGHT-HENNEPIN COOPERATIVE ELECTRIC | Rockford | — | $125.2M | 22 |
| UNIVERSITY OF NORTHWESTERN - ST PAUL | St Paul | B420 Education | $124.3M | 11 |
| Grand Itasca Clinic and Hospital | Grand Rapids | E20Z Health Care | $122.2M | 16 |
| College of Saint Benedict | Saint Joseph | B420 Education | $118.9M | 12 |
| CONCORDIA COLLEGE CORPORATION | Moorhead | — | $116.9M | 9 |
| SPIRE CREDIT UNION | Falcon Heights | — | $116.3M | 11 |
| LAKE COUNTRY POWER | Cohasset | — | $114.8M | 17 |
| CONCORDIA UNIVERSITY ST PAUL | St Paul | — | $112.8M | 11 |
| TRUSTEES OF THE HAMLINE UNIVERSITY | St Paul | B430 Education | $111.8M | 12 |
| Winona Health Services | Winona | E220 Health Care | $110.5M | 15 |
| COLLEGE OF ST SCHOLASTICA INC | Duluth | B420 Education | $109.5M | 8 |
| MINNESOTA PUBLIC RADIO | St Paul | A340 Arts, Culture & Humanities | $108.7M | 18 |
| MINNESOTA VALLEY ELECTRIC COOPERATIVE | Jordan | — | $108.6M | 22 |
