| THRIVENT FINANCIAL FOR LUTHERANS-GROUP | Minneapolis | — | $49M | 0 |
| ELIM HOMES INC | Edina | — | $48.9M | 12 |
| Ruby's Heart | North Branch | X20 Religion-Related | $48.5M | 2 |
| United Hospital District | Blue Earth | E20 Health Care | $46.9M | 20 |
| UCARE HEALTH INC | Minneapolis | E99 Health Care | $46.9M | 7 |
| NU-WAY HOUSE | Minneapolis | — | $46.6M | 10 |
| WEST SIDE COMMUNITY HEALTH SERVICES | St Paul | E30 Health Care | $46M | 11 |
| MINNESOTA MASTERPIECE HALL | Winona | A20 Arts, Culture & Humanities | $45.9M | 1 |
| MINNEAPOLIS COLLEGE OF ART AND DESIGN | Minneapolis | B430 Education | $45.8M | 9 |
| ST PAUL ACADEMY AND SUMMIT SCHOOL | Saint Paul | B200 Education | $45.8M | 7 |
| ECUMEN SBC INC | Shoreview | — | $45.3M | 5 |
| HENNEPIN THEATRE TRUST | Minneapolis | A65 Arts, Culture & Humanities | $45.1M | 5 |
| STEELE-WASECA COOPERATIVE ELECTRIC | Owatonna | — | $45M | 16 |
| INDEPENDENT COMMUNITY BANKERS OF AMERICA | Sauk Centre | — | $44.9M | 37 |
| Ebenezer Society | Edina | E910 Health Care | $44.7M | 9 |
| FRASER | Richfield | P730 Human Services | $44.6M | 7 |
| GARDEN VALLEY TELEPHONE COMPANY | Erskine | — | $44.3M | 16 |
| ALLINA HEALTH FOUNDATION | Minneapolis | E11 Health Care | $44.2M | 3 |
| AMERICAN ACADEMY OF NEUROLOGY | Minneapolis | S46 Community Improvement & Capacity Building | $44.1M | 17 |
| MOUNT OLIVET ROLLING ACRES INC | Victoria | P730 Human Services | $44.1M | 4 |
| Hammer Residences Inc | Wayzata | P700 Human Services | $44.1M | 8 |
| THE BUSH FOUNDATION | St Paul | B80 Education | $43.9M | 18 |
| CENTRACARE HEALTH SYSTEM - SAUK CENTRE | Sauk Centre | E20 Health Care | $43.8M | 15 |
| PAINTERS AND ALLIED TRADES DISTRICT | Bloomington | — | $43.7M | 7 |
| FEDERATED RURAL ELECTRIC | Jackson | — | $43.6M | 14 |
| DEER RIVER HEALTHCARE CENTER INC | Deer River | E20Z Health Care | $43.6M | 11 |
| HILL MUSEUM & MANUSCRIPT LIBRARY | Collegeville | B70 Education | $43.5M | 2 |
| TOPLINE FINANCIAL CREDIT UNION | Maple Grove | W61 Public & Societal Benefit | $42.9M | 7 |
| GREATER TWIN CITIES UNITED WAY | Minneapolis | T70 Philanthropy, Voluntarism & Grantmaking Foundations | $42.8M | 12 |
| SCHOLARSHIP AMERICA INC | Minneapolis | B820 Education | $42.8M | 0 |
| BETHESDA | Willmar | E91Z Health Care | $42.7M | 7 |
| THE FOUNDATION FOR HEALTH CARE | Sartell | E91 Health Care | $42.5M | 12 |
| Hmong College Prep Academy | St Paul | B29 Education | $42.5M | 4 |
| Think Small | Saint Paul | P33I Human Services | $41.9M | 5 |
| KATHERINE WELLS MACMILLAN FOUNDATION | Minneapolis | B82 Education | $41.8M | 0 |
| CONSOLIDATED TELEPHONE COMPANY | Brainerd | — | $41.7M | 18 |
| MINNEAPOLIS RETAIL MEAT CUTTERS AND FOOD | Bloomington | — | $41.7M | 5 |
| LYNGBLOMSTEN CARE CENTER INC | St Paul | — | $41.4M | 8 |
| Community Action Partnership of Ramsey | St Paul | — | $41.4M | 4 |
| CENTRACARE HEALTH SYSTEM - LONG PRAIRIE | Long Prairie | E21 Health Care | $41.4M | 15 |
| The Hormel Foundation | Austin | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $40.8M | 18 |
| NORTHWEST AREA FOUNDATION | St Paul | — | $40.6M | 18 |
| ESSENTIA HEALTH MOOSE LAKE | Moose Lake | E20 Health Care | $40.5M | 14 |
| HEALTHPARTNERS RC | Bloomington | E22 Health Care | $40.2M | 14 |
| MINNEAPOLIS JEWISH FEDERATION | Minneapolis | T700 Philanthropy, Voluntarism & Grantmaking Foundations | $39.8M | 5 |
| VOLUNTEERS OF AMERICA CARE FACILITIES | Eden Prairie | P750 Human Services | $39.6M | 15 |
| UTILITY WORKERS UNION OF AMERICA | Bloomington | Y43 Mutual & Membership Benefit | $39.4M | 3 |
| BOREALIS PHILANTHROPY | Minneapolis | A99 Arts, Culture & Humanities | $39.4M | 8 |
| EDUCATION MINNESOTA | St Paul | J40 Employment | $39.1M | 14 |
| SERVICE MANAGEMENT GROUP INC | Minnetonka | P44 Human Services | $39M | 19 |
