| CATHOLIC UNITED FINANCIAL | Arden Hills | — | $67.6M | 15 |
| DISTRICT ENERGY ST PAUL INC | St Paul | W800 Public & Societal Benefit | $67M | 11 |
| JOYFUL NOISE CHARITABLE FOUNDATION | Minneapolis | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $66.7M | 0 |
| PLANNED PARENTHOOD NORTH CENTRAL STATES | St Paul | E42 Health Care | $66.6M | 13 |
| COTTER SCHOOLS | Winona | — | $66M | 3 |
| PEOPLE INCORPORATED | Eagan | — | $65.9M | 7 |
| AMHERST H WILDER FOUNDATION | St Paul | P400 Human Services | $65.2M | 14 |
| MEMBERS COOPERATIVE CREDIT UNION | Duluth | — | $65.2M | 22 |
| MANITOU FUND | White Bear Lake | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $65.2M | 3 |
| MILLE LACS HEALTH SYSTEM | Onamia | E220 Health Care | $63.5M | 18 |
| IDEAL CREDIT UNION | Woodbury | — | $63.1M | 30 |
| RIVERVIEW HEALTHCARE ASSOCIATION | Crookston | E22 Health Care | $62.9M | 13 |
| CRITICAL CARE SERVICES INC | Arden Hills | E62 Health Care | $62.5M | 10 |
| MITCHELL HAMLINE SCHOOL OF LAW | St Paul | B500 Education | $61.7M | 8 |
| BELTRAMI ELECTRIC COOPERATIVE INC | Bemidji | — | $61.3M | 16 |
| ALIGHT | Minneapolis | Q710 International, Foreign Affairs & National Security | $61.3M | 8 |
| FREEBORN MOWER ELECTRIC COOPERATIVE | Albert Lea | Y22 Mutual & Membership Benefit | $60.3M | 15 |
| LAKE REGION ELECTRIC COOPERATIVE | Pelican Rapids | — | $59.5M | 18 |
| SENIOR CARE COMMUNITIES INC | St Paul | E910 Health Care | $58.4M | 8 |
| PEOPLE'S COOPERATIVE SERVICES | Oronoco | — | $58.3M | 14 |
| ECMC FOUNDATION | Minneapolis | B02 Education | $58.2M | 11 |
| THE BLAKE SCHOOL | Hopkins | B200 Education | $58.2M | 7 |
| THE GOODMAN FAMILY OPERATING FOUNDATION | Chaska | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $58.1M | 0 |
| ST PAUL ELECTRICAL WORKERS WELFARE FUND | St Paul | — | $57.5M | 5 |
| Catholic Charities of the Archdiocese of Saint Paul and Minneapolis | Minneapolis | P200 Human Services | $57.1M | 13 |
| SOUTHERN MINNESOTA ENERGY COOPERATIVE | Rushford | Y22 Mutual & Membership Benefit | $56.6M | 1 |
| CITY & COUNTY CREDIT UNION | Saint Paul | — | $56.6M | 23 |
| CAR DONATION FOUNDATION | St Louis Park | T12 Philanthropy, Voluntarism & Grantmaking Foundations | $56.2M | 1 |
| TWIN CITIES HABITAT FOR HUMANITY INC | St Paul | — | $56.1M | 11 |
| Breck School | Golden Valley | B200 Education | $55.8M | 13 |
| TOPLINE FINANCIAL CREDIT UNION | Maple Grove | W61 Public & Societal Benefit | $55.6M | 7 |
| DUNWOODY COLLEGE OF TECHNOLOGY | Minneapolis | B300 Education | $55.4M | 11 |
| ELIM HOMES INC | Edina | — | $55.4M | 12 |
| KIDS IN NEED FOUNDATION | Little Canada | B12 Education | $55M | 5 |
| MATTER | St Louis Park | K30 Food, Agriculture & Nutrition | $54.9M | 5 |
| United Hospital District | Blue Earth | E20 Health Care | $54.8M | 21 |
| HENNEPIN HEALTHCARE RESEARCH INSTITUTE | Minneapolis | H90 Medical Research | $54.7M | 18 |
| SAINT ELIZABETH'S HOSPITAL OF WABASHA | Wabasha | E200 Health Care | $54.6M | 14 |
| Stevens Community Medical Center | Morris | E22 Health Care | $54.1M | 20 |
| WALKER ART CENTER | Minneapolis | A200 Arts, Culture & Humanities | $53.5M | 10 |
| Bella Mente Quantum Racing Association | Minneapolis | N70 Recreation & Sports | $53.4M | 7 |
| Central Minnesota Diagnostic Inc | Milaca | E220 Health Care | $53.3M | 8 |
| BLUE EARTH-NICOLLET-FARIBAULT COOPERATIVE ELECTRIC ASSOCIATION | Mankato | — | $53.2M | 16 |
| HEALTHPARTNERS INSTITUTE | Minneapolis | E110 Health Care | $52.6M | 10 |
| TRELLIS CO | Minneapolis | L20Z Housing & Shelter | $52.4M | 8 |
| COMMONBOND COMMUNITIES | Saint Paul | — | $52.4M | 6 |
| MINNESOTA LABORERS VACATION FUND | Mendota Heights | — | $51.8M | 4 |
| TWIN CITIES PUBLIC TELEVISION INC | Saint Paul | A320 Arts, Culture & Humanities | $51.8M | 15 |
| PARENTS IN COMMUNITY ACTION INC | Minneapolis | P200 Human Services | $51.5M | 8 |
| CENTRACARE HEALTH SYSTEM - MELROSE | Melrose | E22Z Health Care | $51.4M | 16 |
