| GUARDIANS OF THE SICK INC | Brooklyn | E80Z Health Care | $27.8M | 1 |
| MONA BISMARCK AMERICAN CENTER FOR ART AND CULTURE INC C/O EWENSTEIN&ROTH LLP | New York | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $27.8M | 0 |
| GLOBAL HEALTH INVESTMENT CORPORATION | New York | E12 Health Care | $27.8M | 9 |
| CRAFT DIVISION OF LOCAL 1049 HEALTH AND WELFARE FUND | Holtsville | — | $27.7M | 1 |
| THE QUAD PREPARATORY SCHOOL | New York | B20 Education | $27.7M | 9 |
| FEDERAL DEFENDERS OF NEW YORK INC | New York | I80 Crime & Legal-Related | $27.7M | 9 |
| NATIONAL ALLIANCE FOR RESEARCH ON SCHIZOPHRENIA AND DEPRESSION | New York | — | $27.7M | 7 |
| THE INTERNATIONAL ACADEMY OF HOPE | New York | H48 Medical Research | $27.7M | 8 |
| GATEWAY-LONGVIEW INC | Williamsville | P82Z Human Services | $27.7M | 7 |
| PORTLEDGE SCHOOL | Locust Valley | — | $27.7M | 13 |
| AFS-USA INC | New York | Q220 International, Foreign Affairs & National Security | $27.7M | 7 |
| LI Child and Family Development Services Inc | Patchogue | — | $27.6M | 3 |
| FOUNDATION FOR A JUST SOCIETY | New York | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $27.6M | 4 |
| SHEA'S O'CONNELL PRESERVATION GUILD LTD D/B/A SHEA'S PERFORMING ARTS CENTER | Buffalo | A610 Arts, Culture & Humanities | $27.6M | 1 |
| TRINITY-PAWLING SCHOOL CORPORATION | Pawling | B200 Education | $27.5M | 12 |
| TREEHOUSE FAMILY FOUNDATION | New York | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $27.5M | 0 |
| FRANCISCAN SERVICES INC | Hamburg | B42 Education | $27.5M | 6 |
| HUMAN TECHNOLOGIES CORPORATION | Utica | J330 Employment | $27.5M | 11 |
| FRANKLIN UNIVERSITY SWITZERLAND INC | New York | B42Z Education | $27.5M | 1 |
| BEST CHOICE HOME HEALTH CARE INC | Flushing | E99Z Health Care | $27.4M | 11 |
| CEREBRAL PALSY OF WESTCHESTER INC | Rye Brook | G200 Diseases, Disorders & Medical Disciplines | $27.4M | 8 |
| COMMUNITY PARTNERSHIP CHARTER SCHOOL EDUCATION CORPORATION | Brooklyn | B29 Education | $27.3M | 12 |
| ARNOT MEDICAL SERVICES PLLC | Elmira | E30 Health Care | $27.3M | 5 |
| CFS SELF-DIRECTED SUPPORTS INC | New York | P20 Human Services | $27.3M | 6 |
| COMMUNITY DEVELOPMENT CORPORATION OF LONG ISLAND INC | Melville | S200 Community Improvement & Capacity Building | $27.2M | 11 |
| Young Men's Christian Association of Central New York Inc | Syracuse | P27Z Human Services | $27.1M | 6 |
| International Trademark Association Inc | New York | — | $27.1M | 8 |
| SAINTS JOACHIM & ANNE NURSING & REHABILITATION CENTER | Brooklyn | — | $27.1M | 9 |
| AHIVIM INC | Monroe | E60 Health Care | $27.1M | 6 |
| OPTIONS FOR COMMUNITY LIVING INC | Ronkonkoma | F33Z Mental Health & Crisis Intervention | $27.1M | 7 |
| STANLEY G FALK SCHOOL | Buffalo | — | $27M | 7 |
| NATIONAL MUSEUM OF MATHEMATICS | New York | A50 Arts, Culture & Humanities | $27M | 7 |
| TIMES SQUARE DISTRICT MANAGEMENT ASSOCIATION | New York | Z99Z Unknown | $27M | 10 |
| INWOOD ACADEMY FOR LEADERSHIP CHARTER SCHOOL | New York | B29 Education | $26.9M | 8 |
| ENTERPRISE ASSOCIATION LOCAL 638 | Long Island City | — | $26.9M | 27 |
| NEAR EAST FOUNDATION | Syracuse | Q300 International, Foreign Affairs & National Security | $26.9M | 6 |
| NYSARC INC SARATOGA COUNTY CHAPTER | Ballston Spa | P82Z Human Services | $26.8M | 5 |
| UNION SETTLEMENT ASSOCIATION INC | New York | P200 Human Services | $26.8M | 8 |
| TGM REALTY CORP#20 | New York | S47 Community Improvement & Capacity Building | $26.8M | 6 |
| HEALTHIX INC | New York | W050 Public & Societal Benefit | $26.8M | 11 |
| BROTHERS OF MERCY NURSING HOME COMPANY INC | Clarence | — | $26.8M | 10 |
| YAD ELKA INC | Brooklyn | K31 Food, Agriculture & Nutrition | $26.7M | 0 |
| THE ANDY WARHOL FOUNDATION FOR THE VISUAL ARTS INC | New York | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $26.7M | 22 |
| AUXILIARY SERVICES STATE UNIVERSITY COLLEGE AT OSWEGO INC | Oswego | B43I Education | $26.7M | 2 |
| University Communications Network Inc | New York | A32 Arts, Culture & Humanities | $26.6M | 1 |
| LOCAL 342 HEALTH CARE FUND | Bohemia | — | $26.6M | 2 |
| BUFFALO FINE ARTS ACADEMY | Buffalo | A510 Arts, Culture & Humanities | $26.6M | 8 |
| PROJECT LIBERTY INSTITUTE | New York | U05 Science & Technology | $26.6M | 5 |
| THE SALTZMAN FOUNDATION INC | New York | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $26.5M | 0 |
| Dominion Energy Inc Ohio Gas Union VEBA Trust | New York | — | $26.5M | 0 |
