| GOVERNMENT EMPLOYEES ASSOCIATION INC | Cleveland | — | $26.6M | 0 |
| SECOND HARVEST FOODBANK OF NORTH CENTRAL OHIO | Lorain | K310 Food, Agriculture & Nutrition | $26.6M | 1 |
| OHIO HIGH SCHOOL ATHLETIC ASSOCIATION | Columbus | N400 Recreation & Sports | $26.5M | 6 |
| UNIVERSAL 1 CREDIT UNION | Dayton | — | $26.4M | 12 |
| UNISON BEHAVIORAL HEALTH GROUP INC | Toledo | E30Z Health Care | $26.4M | 7 |
| THE UNIVERSITY OF AKRON FOUNDATION | Akron | B110 Education | $26.4M | 4 |
| IMPACT COMMUNITY ACTION INC | Columbus | S20 Community Improvement & Capacity Building | $26.2M | 3 |
| LAUREL SCHOOL | Shaker Heights | B200 Education | $26.2M | 8 |
| OHIO'S HOSPICE INC | Dayton | E19 Health Care | $26.1M | 18 |
| BELLEVUE GARDENS COMMUNITY URBAN REDEVELOPMENT CORPORATION | Cincinnati | — | $26.1M | 0 |
| GATEWAYS TO BETTER LIVING INC | Youngstown | P73Z Human Services | $25.8M | 2 |
| AMISH HELPING FUND | Millersburg | — | $25.8M | 9 |
| BETHESDA HEALTHCARE INC | Cincinnati | E320 Health Care | $25.7M | 12 |
| FRANKLIN COUNTY HISTORICAL SOCIETY DBA COSI COLUMBUS | Columbus | A80 Arts, Culture & Humanities | $25.4M | 8 |
| SJO KIDS INC | Cincinnati | P30 Human Services | $25.4M | 5 |
| GREENFIELD AREA MEDICAL CENTER | Greenfield | — | $25.4M | 11 |
| COMMUNITY HOSPITALS AND WELLNESS CENTERS | Bryan | E220 Health Care | $25.3M | 17 |
| LIFECARE ALLIANCE | Columbus | K30Z Food, Agriculture & Nutrition | $25.2M | 1 |
| MIDWEST COMMUNITY HEALTH ASSOCIATES INC | Bryan | — | $25.2M | 10 |
| COMMUNITY DIALYSIS CENTER | Shaker Heights | E300 Health Care | $25.2M | 4 |
| AKRON ZOOLOGICAL PARK | Akron | D500 Animal-Related | $25.2M | 10 |
| The Progressive Insurance Foundation | Cleveland | T21 Philanthropy, Voluntarism & Grantmaking Foundations | $25.1M | 0 |
| FIRELANDS ELECTRIC COOPERATIVE INC | New London | — | $25.1M | 19 |
| COUNTRY CLUB INC | Pepper Pike | — | $25.1M | 6 |
| ANNE GRADY CORPORATION | Holland | P730 Human Services | $25.1M | 4 |
| PROMEDICA MULTI SPECIALTY PHYSICIANS | Toledo | E30 Health Care | $25.1M | 7 |
| NCC SOLUTIONS INC | North Royalton | F33 Mental Health & Crisis Intervention | $25M | 13 |
| MURTIS TAYLOR HUMAN SERVICES SYSTEM | Cleveland | F30Z Mental Health & Crisis Intervention | $24.9M | 7 |
| The Centers for Families and Children | Cleveland | P200 Human Services | $24.9M | 6 |
| JOHN HENRY ELDRED JR FOUNDATION | Toledo | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $24.9M | 1 |
| AXESS FAMILY SERVICES INC | Ravenna | E20Z Health Care | $24.8M | 11 |
| CHOICES BEHAVIORAL HEALTH CARE | Toledo | I11 Crime & Legal-Related | $24.8M | 2 |
| AKRON SUMMIT COMMUNITY ACTION INC | Akron | — | $24.8M | 6 |
| AMERICAN FRIENDS OF OGEN INC | University Heights | S41Z Community Improvement & Capacity Building | $24.7M | 0 |
| THE MCGREGOR FOUNDATION | East Cleveland | — | $24.7M | 8 |
| THE MONTEFIORE HOME | Beachwood | E910 Health Care | $24.5M | 8 |
| OWENS CORNING FOUNDATION | Toledo | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $24.5M | 0 |
| CARING PARTNERS INTERNATIONAL INC | Franklin | Q300 International, Foreign Affairs & National Security | $24.5M | 2 |
| WESTERN RESERVE REVITALIZATION AND MANAGEMENT COMPANY INC | Cleveland | L20 Housing & Shelter | $24.5M | 4 |
| JAY AND JEAN SCHOTTENSTEIN FOUNDATION | Columbus | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $24.4M | 0 |
| UNITED WAY OF CENTRAL OHIO INC | Columbus | T700 Philanthropy, Voluntarism & Grantmaking Foundations | $24.3M | 9 |
| STRS OHIO TX REAL ESTATE INVESTMENTS INC | Columbus | S47 Community Improvement & Capacity Building | $24.3M | 0 |
| ST LUKE'S HOSPITAL | Maumee | E220 Health Care | $24.2M | 19 |
| Election Freedom Inc | Columbus | — | $24.2M | 0 |
| WASHINGTON ELECTRIC COOPERATIVE IN | Marietta | — | $24.2M | 13 |
| PSA 3 AGENCY ON AGING | Lima | — | $24.1M | 3 |
| YMCA of Central Stark County | Canton | P27Z Human Services | $24.1M | 4 |
| West Side Deutscher Frauen Verein | Strongsville | E910 Health Care | $24M | 4 |
| TRUTH FOR LIFE | Solon | X20 Religion-Related | $24M | 4 |
| BEECH ACRES | Cincinnati | P300 Human Services | $24M | 8 |
