| EMBERS CREDIT UNION | Marquette | — | $29.9M | 8 |
| MARWOOD MANOR NURSING HOME | Port Huron | — | $29.8M | 8 |
| GOODWILL INDUSTRIES OF CENTRAL | Battle Creek | J32Z Employment | $29.7M | 4 |
| ASSOCIATION FOR CHILD DEVELOPMENT | East Lansing | P190 Human Services | $29.7M | 1 |
| MICHIGAN STATE BAR FOUNDATION | Lansing | I128 Crime & Legal-Related | $29.6M | 3 |
| INVEST DETROIT FOUNDATION | Detroit | S30 Community Improvement & Capacity Building | $29.6M | 8 |
| PEOPLE DRIVEN CREDIT UNION | Southfield | — | $29.4M | 12 |
| PIPEFITTERS LOCAL NO 636 | Troy | — | $29.2M | 0 |
| PORTER HILLS PRESBYTERIAN VILLAGE INC | Grand Rapids | P75Z Human Services | $29.1M | 9 |
| GOODWILL INDUSTRIES OF GREATER DETROIT | Detroit | J32Z Employment | $29.1M | 4 |
| SACRED HEART REHABILITATION | Memphis | F220 Mental Health & Crisis Intervention | $29M | 4 |
| Faith Hospice | Byron Center | E92Z Health Care | $29M | 7 |
| MICHIGAN HUMANE SOCIETY | Detroit | D200 Animal-Related | $29M | 10 |
| OAKLAND LIVINGSTON HUMAN SERVICE AGENCY | Pontiac | P200 Human Services | $28.9M | 4 |
| THE WASHTENAW PACE INC | Ypsilanti | E60 Health Care | $28.8M | 10 |
| COMMUNITY LIVING NETWORK INC | Ypsilanti | E50 Health Care | $28.7M | 2 |
| Upper Great Lakes Family Health Center | Gwinn | E20 Health Care | $28.6M | 8 |
| THE HOPE FOUNDATION | Ann Arbor | G99Z Diseases, Disorders & Medical Disciplines | $28.6M | 6 |
| REGION IV AREA AGENCY ON AGING INC | St Joseph | P81Z Human Services | $28.6M | 1 |
| ORCHARDS CHILDRENS SERVICES INC | Southfield | P30Z Human Services | $28.6M | 5 |
| William Davidson Foundation | Birmingham | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $28.5M | 2 |
| JEWISH FAMILY SERVICE | West Bloomfield | P40Z Human Services | $28.4M | 6 |
| KALAMAZOO PROMISE | Kalamazoo | B82 Education | $28.1M | 0 |
| Michigan Carpenters Health Care Fund | Lansing | — | $28M | 4 |
| COMMON GROUND | Bingham Farms | F40Z Mental Health & Crisis Intervention | $27.9M | 7 |
| CSI SUPPORT & DEVELOPMENT SERVICES | Warren | L02 Housing & Shelter | $27.9M | 7 |
| GRAND RAPIDS COMMUNITY FOUNDATION | Grand Rapids | T310 Philanthropy, Voluntarism & Grantmaking Foundations | $27.9M | 8 |
| BAC of Michigan Health and Welfare Fund | Troy | — | $27.8M | 8 |
| CAPITAL AREA COMMUNITY SERVICES INC | Lansing | — | $27.7M | 7 |
| Cleary University | Howell | B42Z Education | $27.7M | 7 |
| Michigan Advocacy Program | Ypsilanti | I800 Crime & Legal-Related | $27.6M | 10 |
| REGION II COMMISSION ON SERVICES TO | Brooklyn | P81Z Human Services | $27.5M | 13 |
| LANSING ECONOMIC AREA PARTNERSHIP | Lansing | S41 Community Improvement & Capacity Building | $27.5M | 4 |
| NORTHWEST MICHIGAN COMMUNITY ACTION | Traverse City | P200 Human Services | $27.4M | 2 |
| BURCHAM HILLS RETIREMENT CENTER II | East Lansing | P750 Human Services | $27.3M | 1 |
| LIFECARE INC | Kalamazoo | P750 Human Services | $27.2M | 6 |
| LUTHERAN CHILD & FAMILY SERVICE OF | Saginaw | P200 Human Services | $27.1M | 0 |
| LEADER DOGS FOR THE BLIND | Rochester Hills | P860 Human Services | $27M | 11 |
| PACE OF SOUTHWEST MICHIGAN INC | St Joseph | P75 Human Services | $26.9M | 6 |
| MICHIGAN REGIONAL COUNCIL OF | Detroit | — | $26.9M | 15 |
| MOUNT ELLIOTT CEMETERY ASSOCIATION | Detroit | Y52Z Mutual & Membership Benefit | $26.9M | 16 |
| Cascade Hemophilia Consortium | Ann Arbor | E66Z Health Care | $26.8M | 1 |
| MIDWEST COLLABORATIVE FOR LIBRARY | Lansing | B71I Education | $26.7M | 2 |
| RIVER CITY FOUNDATION | Dexter | — | $26.6M | 0 |
| Plumbers & Pipefitters Local 520 Health & Welfare Fund | Troy | — | $26.5M | 0 |
| UAW CHRYSLER SKILL DEVELOPMENT | Warren | — | $26.5M | 5 |
| PLANNED PARENTHOOD OF MICHIGAN | Ann Arbor | E42 Health Care | $26.4M | 13 |
| A & D CHARITABLE FOUNDATION INC | Saginaw | E92 Health Care | $26.4M | 7 |
| MOKA CORPORATION | Muskegon | P73Z Human Services | $26.3M | 2 |
| DETROIT PUBLIC MEDIA | Wixom | A320 Arts, Culture & Humanities | $26.2M | 9 |