| PERFORMANCE REVIEW INSTITUTE INC | Warrendale | — | $62.5M | 8 |
| FAYETTE RESOURCES INC | Uniontown | P820 Human Services | $61.8M | 6 |
| ALBRIGHT COLLEGE | Reading | B420 Education | $61.7M | 9 |
| THE PUBLIC SCHOOL OF GERMANTOWN | Fort Washington | B200 Education | $61.7M | 7 |
| Deere & Company WFT #2 | Pittsburgh | Y43 Mutual & Membership Benefit | $61.7M | 1 |
| MASTERY CHARTER HIGH SCHOOL | Philadelphia | B29 Education | $61.6M | 15 |
| WESTERN PENNSYLVANIA ELECTRICAL | Pittsburgh | — | $61.5M | 0 |
| LUTHERCARE | Lititz | P750 Human Services | $61.4M | 11 |
| SHADY SIDE ACADEMY | Pittsburgh | B200 Education | $61.3M | 12 |
| WESTMINSTER COLLEGE | New Wilmington | B420 Education | $60.9M | 10 |
| IUPAT DISTRICT COUNCIL NO 21 | Philadelphia | — | $60.8M | 9 |
| PHILADELPHIA FIGHT | Philadelphia | H20Z Medical Research | $60.6M | 10 |
| SKILLS OF CENTRAL PENNSYLVANIA INC | State College | P82Z Human Services | $60.6M | 4 |
| LINCOLN UNIVERSITY | Lincoln University | B430 Education | $60.3M | 13 |
| THE HILL SCHOOL | Pottstown | B250 Education | $60.2M | 8 |
| CONCORDIA LUTHERAN HEALTH AND HUMAN CARE | Cabot | P750 Human Services | $60.1M | 16 |
| HR PHYSICIAN SERVICES | Huntingdon Valley | E60 Health Care | $60M | 12 |
| GEISINGER MEDICAL CENTER MUNCY | Danville | E20 Health Care | $59.6M | 9 |
| Employment Partners Benefits Fund | Bridgeville | — | $59.4M | 1 |
| ST LUKE'S HOSPITAL - EASTON CAMPUS | Allentown | E20 Health Care | $59.4M | 2 |
| United States Steel Corporation Represented Retirees Benefit Trust | Pittsburgh | — | $59.4M | 1 |
| MESSIAH HOME | Mechanicsburg | P750 Human Services | $59.2M | 9 |
| TITUSVILLE AREA HOSPITAL | Titusville | E22 Health Care | $59M | 7 |
| JC BLAIR MEMORIAL HOSPITAL | Huntingdon | E220 Health Care | $58.6M | 6 |
| CLARION HOSPITAL | Clarion | E220 Health Care | $58.3M | 9 |
| HEALTH FEDERATION OF PHILADELPHIA | Philadelphia | — | $58.2M | 6 |
| LIVING INDEPENDENCE FOR THE ELDERLY | Pittsburgh | P810 Human Services | $58.1M | 10 |
| SPRINGSIDE CHESTNUT HILL ACADEMY | Philadelphia | B200 Education | $57.8M | 8 |
| PENNSYLVANIA ASSOCIATION OF AREA | Harrisburg | — | $57.8M | 2 |
| CENTRAL PENNSYLVANIA BEHAVIORAL HEALTH | Hollidaysburg | F20 Mental Health & Crisis Intervention | $57.5M | 2 |
| THE PHILADELPHIA FOUNDATION | Philadelphia | T310 Philanthropy, Voluntarism & Grantmaking Foundations | $57.3M | 7 |
| CENTRAL SUSQUEHANNA REGION SCHOOL | Milton | — | $57.2M | 0 |
| PENNSYLVANIA TRUST | Milton | — | $57.1M | 0 |
| SALUS UNIVERSITY | Elkins Park | — | $57.1M | 12 |
| SHEET METAL WORKERS HEALTH FUND OF | Philadelphia | — | $56.9M | 7 |
| LANDIS HOMES RETIREMENT COMMUNITY | Lititz | P750 Human Services | $56.6M | 6 |
| WINDBER HOSPITAL INC | Windber | E220 Health Care | $56.5M | 11 |
| PENNSYLVANIA VIRTUAL CHARTER SCHOOL | King Of Prussia | B99 Education | $56.4M | 5 |
| CHOICES HEALTHCARE | Lancaster | P740 Human Services | $56.3M | 14 |
| ADELPHOI VILLAGE INC | Latrobe | P300 Human Services | $56.3M | 8 |
| SHARE FOOD PROGRAM | Philadelphia | K31Z Food, Agriculture & Nutrition | $56.2M | 6 |
| PUNXSUTAWNEY AREA HOSPITAL INC | Punxsutawney | E22Z Health Care | $55.9M | 11 |
| CONCORDIA LUTHERAN MINISTRIES OF PITTSBURGH | Pittsburgh | L22 Housing & Shelter | $55.5M | 11 |
| HAVERFORD SCHOOL | Haverford | B24Z Education | $55.5M | 12 |
| EAGLEVILLE HOSPITAL | Eagleville | E220 Health Care | $55.4M | 7 |
| UNITED CEREBRAL PALSY OF | Camp Hill | — | $55.3M | 5 |
| UFCW 1776 & PARTICIPATING EMPLOYERS | Plymouth Meeting | — | $55.2M | 0 |
| PITTSBURGH SYMPHONY INC | Pittsburgh | A690 Arts, Culture & Humanities | $55.2M | 10 |
| THE FUND FOR CHARITABLE GIVING | Pittsburgh | T99 Philanthropy, Voluntarism & Grantmaking Foundations | $55M | 1 |
| BRETHREN VILLAGE | Lititz | P750 Human Services | $54.8M | 7 |
