| ALFRED UNIVERSITY | Alfred | B430 Education | $106M | 11 |
| FEDCAP REHABILITATION SERVICES INC | New York | — | $106M | 9 |
| Lifespire Inc | New York | P820 Human Services | $105.7M | 9 |
| DEMOCRACY PREP NEW YORK CHARTER SCHOOLS | Bronx | B24 Education | $105.6M | 7 |
| ISLAND PEER REVIEW ORGANIZATION INC | New Hyde Park | W200 Public & Societal Benefit | $105.6M | 30 |
| BNA Prefunded VEBA Trust | Brooklyn | — | $105.5M | 1 |
| SPORTS PHYSICAL THERAPY OCCUPATIONAL THERAPY AND REHAB SERVICES OF NORTH SHORE PLLC | Westbury | E50 Health Care | $105M | 12 |
| The Hebrew Home for Aged at Riverdale | Bronx | E90 Health Care | $104.9M | 8 |
| CLNY ALLIANCE INC | Westbury | E19 Health Care | $104.7M | 9 |
| LINCOLN CENTER DEVELOPMENT PROJECT INC | New York | A99 Arts, Culture & Humanities | $104.6M | 5 |
| NURSING SISTERS HOME CARE INC | Farmingdale | E92Z Health Care | $104.3M | 7 |
| CANISIUS UNIVERSITY | Buffalo | B430 Education | $103.8M | 14 |
| Puerto Rican Organization to Motivate Enlighten and Serve Addicts Inc | Bronx | F220 Mental Health & Crisis Intervention | $103.4M | 11 |
| NEW YORK STATE TECHNOLOGY ENTERPRISE CORPORATION | Rome | Z99 Unknown | $102.9M | 21 |
| MURMURATION RESEARCH INSTITUTE INC | New York | W99 Public & Societal Benefit | $102.7M | 12 |
| JUSTICE INNOVATION INC | New York | I50 Crime & Legal-Related | $102.6M | 8 |
| SELFHELP COMMUNITY SERVICES INC | New York | P20 Human Services | $102.3M | 13 |
| HARLEM CHILDREN'S ZONE INC | New York | P300 Human Services | $101.8M | 12 |
| COORDINATED BEHAVIORAL CARE INC | New York | B99 Education | $101.7M | 5 |
| CATHOLIC CHARITIES OF THE DIOCESE OF ROCHESTER | Rochester | — | $101.5M | 7 |
| NDC HOUSING & ECONOMIC DEVELOPMENT CORPORATION - GROUP RETURN | New York | L200 Housing & Shelter | $101.5M | 11 |
| WHITNEY MUSEUM OF AMERICAN ART | New York | A510 Arts, Culture & Humanities | $100.9M | 12 |
| HELIO HEALTH INC | Syracuse | F220 Mental Health & Crisis Intervention | $100.8M | 8 |
| University Associates in Obstetrics and Gynecology University Faculty Pract ice Corporation | Stony Brook | E20 Health Care | $100.7M | 9 |
| MOUNT SINAI HEALTH SYSTEM INC | New York | P20 Human Services | $100.3M | 10 |
| WORLD EDUCATION SERVICES INC | New York | Q22Z International, Foreign Affairs & National Security | $99.9M | 15 |
| ISABELLA GERIATRIC CENTER INC | New York | P750 Human Services | $99.9M | 9 |
| D'YOUVILLE UNIVERSITY | Buffalo | B430 Education | $99.7M | 6 |
| AMERICAN KENNEL CLUB INC | New York | D60 Animal-Related | $99.6M | 23 |
| CHARLES B WANG COMMUNITY HEALTH CENTER INC | New York | E30Z Health Care | $99.6M | 10 |
| INDEPENDENT LIVING FOR SENIORS INC | Rochester | X00Z Religion-Related | $99.4M | 12 |
| SMILE TRAIN INC | New York | — | $99.4M | 11 |
| QSAC INC | New York | G84Z Diseases, Disorders & Medical Disciplines | $99.3M | 8 |
| PLUMBERS LOCAL UNION NO 1 WELFARE FUND | Long Island City | Y43 Mutual & Membership Benefit | $99.1M | 9 |
| UB FOUNDATION ACTIVITIES INC | Buffalo | — | $98.9M | 5 |
| Garnet Health Medical Center - Catskills | Harris | E220 Health Care | $98.5M | 13 |
| HOME LIFE SERVICES INC | Brooklyn | L41 Housing & Shelter | $98.3M | 8 |
| NYSARC INC ULSTER GREENE PUTNAM COUNTY CHAPTERS | Kingston | P820 Human Services | $98.2M | 9 |
| RESOURCE CENTER FOR INDEPENDENT LIVING INC | Utica | P8XZ Human Services | $97.8M | 5 |
| VISITING NURSING ASSOCIATION OF WESTERN NEW YORK INC | Cheektowaga | E92 Health Care | $97.6M | 9 |
| HASC CENTER INC | Brooklyn | P820 Human Services | $97.5M | 14 |
| NEW YORK PSYCHOTHERAPY AND COUNSELING CENTER | Jamaica | F320 Mental Health & Crisis Intervention | $97.4M | 15 |
| NORTH SHORE COMMUNITY SERVICES INC C/O NORTHWELL HEALTH INC | Westbury | — | $97.3M | 11 |
| LAWRENCE MEDICAL ASSOCIATES PC | Bronxville | E30 Health Care | $96.9M | 8 |
| SAFE HORIZON INC | New York | P620 Human Services | $96.7M | 13 |
| ELECTRICAL EMPLOYERS SELF INSURANCE SAFETY PLAN | Flushing | — | $96.4M | 0 |
| FUND FOR PUBLIC HEALTH IN NEW YORK INC | New York | G80 Diseases, Disorders & Medical Disciplines | $96.4M | 6 |
| AURELIA OSBORN FOX MEMORIAL HOSPITAL | Oneonta | E220 Health Care | $96.3M | 8 |
| THE WESTCHESTER MEDICAL PRACTICE PC | Yorktown Heights | E60 Health Care | $96.2M | 7 |
| MJHS HOSPICE AND PALLIATIVE CARE INC | New York | P74 Human Services | $95.7M | 9 |
